Mechanics of Biological Systems and Materials, Volume 7 (eBook)

Proceedings of the 2014 Annual Conference on Experimental and Applied Mechanics

Francois Barthelat, Chad Korach, Pablo Zavattieri, Barton C. Prorok, K. Jane Grande-Allen (Herausgeber)

eBook Download: PDF

2014
VII, 88 Seiten
Springer International Publishing (Verlag)
978-3-319-06974-6 (ISBN)

Infos

Mechanics of Biological Systems and Materials, Volume 7: Proceedings of the 2014 Annual Conference on Experimental and Applied Mechanics, the seventh volume of eight from the Conference, brings together contributions to this important area of research and engineering.  The collection presents early findings and case studies on a wide range of areas, including:

Soft Tissues Mechanics

Natural Materials & Bio-Inspiration

Tissue Engineering

Cells Mechanics

Inhalt

Preface 6
Contents 8
Chapter 1: In Vitro Complex Shear Modulus of Bovine Muscle Tissue 9
1.1 Introduction 9
1.2 Experimental Method 11
1.3 Results and Discussion 12
1.4 Conclusions 14
References 14
Chapter 2: A Camera-Based Experimental Method for Mechanical Test on Patellar Tendons 15
2.1 Introduction 15
2.2 Experimental Set Up and Measurement Procedure 16
2.3 Materials and Methods 18
2.4 Experimental Results 21
2.5 Conclusions 24
References 24
Chapter 3: Thin-Shell Behavior of Mammalian Tympanic Membrane Studied by Digital Holography 26
3.1 Introduction 26
3.2 Thin-Shell Modeling of the TM 27
3.3 Methods to Test the Thin-Shell Theory 28
3.3.1 Shape Measurements 28
3.3.2 3D Displacement Measurements 29
3.4 Results Through Test and Validation of the Thin-Shell Theory 30
3.4.1 Comparisons of the 3D Motion of the TM 30
3.4.2 Resultant Sound-Induced Displacements 30
3.5 Conclusions 31
References 14
Chapter 4: Controlling Abalone Shell Architecture with Temperature 33
4.1 Introduction 33
4.2 Experimental Procedure 34
4.3 Results and Discussion 35
4.4 Conclusions 36
References 37
Chapter 5: The Modeling of Time Dependent Mechanical Properties of Cervine Enamel 38
5.1 Introduction 38
5.2 Material and Methods 39
5.3 Results and Discussion 40
5.4 Conclusion 41
References 41
Chapter 6: Development of Tissue Surrogates for Photoelastic Strain Analysis of Needle Insertion 42
6.1 Introduction 42
6.2 Mechanical Properties of Tissue 43
6.3 Development of a Surrogate Tissue Material 44
6.3.1 Transparency and Birefringence 45
6.3.2 Resistance to Tearing When Punctured 45
6.3.3 Performance Under Load 46
6.3.4 Discussion of Surrogate Material Experiments 46
6.4 Puncture Experiments 47
6.4.1 Phase I: Boundary Displacement 47
6.4.2 Phase II: Tip Insertion 47
6.4.3 Phase III: Tip and Shaft Insertion 48
6.4.4 Puncture Test Procedure 48
6.4.5 Discussion of Puncture Test 48
6.5 Closing Remarks 49
References 49
Chapter 7: Polymer Gels for Defense Applications 51
7.1 Introduction 51
7.2 Experimental 52
7.3 Results and Discussion 52
7.4 Conclusions 54
References 55
Chapter 8: Development of a Microloading Platform for In Vitro Mechanotransduction Studies 56
8.1 Introduction 56
8.2 Methods and Results 57
8.2.1 Development and Characterization of Microloading Platform 57
8.3 Microloading Platform Alignment 59
8.4 PDMS Fabrication 59
8.5 Finite Element Analysis of PDMS Well 59
8.6 Cell Culture 61
8.7 Loading Induced Differential Activity 61
8.8 Discussion 62
References 62
Chapter 9: Development of a Multi-Strain Profile for Cellular Mechanotransduction Testing 63
9.1 Introduction 63
9.2 Experimental Procedure 64
9.2.1 Profile Design 64
9.2.2 Fabrication 65
9.2.3 FEA 65
9.2.4 Physical Test 66
9.3 Results 66
9.3.1 FEA 66
9.3.2 Physical Test 66
9.4 Discussion 68
References 69
Chapter 10: Pull-Off Adhesion Measurements on C. Elegans 70
10.1 Introduction 70
10.2 Experimental Methods 71
10.2.1 C. elegans Growth and Maintenance 71
10.2.2 Experimental Setup 71
10.2.3 Agar Pad Production 71
10.2.4 Pull-Off Experiment 71
10.3 Model 72
10.4 Results and Discussion 73
10.5 Conclusions 74
References 74
Chapter 11: A Fractional Order Model for Local Electric Fields in Tissues 76
11.1 Introduction 76
11.2 Mathematical Model 77
11.3 Results 78
11.4 Conclusion 80
References 80
Chapter 12: Simulation of Atherosclerotic Plaque Delamination Using the Cohesive Zone Model 81
12.1 Introduction 81
12.2 Material Model 82
12.2.1 Bulk Material for the Mouse Aorta 82
12.2.2 Cohesive Model 83
12.3 Numerical Simulations of Atherosclerotic Plaque Delamination 84
12.3.1 Experimental Process and Simulation Model 84
12.3.2 Parameter Identification 85
12.3.2.1 Material Properties of Holzapfel Model 85
12.3.2.2 CZM Material Properties 86
12.4 Prediction and Validation 87
12.5 Conclusions 87
References 88

Produkt-Details

• Erscheint lt. Verlag: 28.7.2014
• Reihe/Serie: Conference Proceedings of the Society for Experimental Mechanics Series
• Reihe/Serie: Conference Proceedings of the Society for Experimental Mechanics Series
• Zusatzinfo: VII, 88 p. 72 illus., 54 illus. in color.
• Verlagsort: Cham
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie
• Themenwelt: Technik ► Bauwesen
• Themenwelt: Technik ► Maschinenbau
• Schlagworte: Biological Materials & Mechanics • Biological Materials & Mechanics • Cell Mechanics • Indentation Methods in Soft Materials • Mechanics of Biomimetic Materials • Mechanics of Bone and Related Materials • Mechanics of Brain Tissues and Structures • Mechanics of Soft Materials and Tissues • Mechanics of Tissue Damage • Multi-scale Mechanics of Natural Fibers • SEM 2014
• ISBN-10: 3-319-06974-8 / 3319069748
• ISBN-13: 978-3-319-06974-6 / 9783319069746