Clostridial Diseases of Animals (eBook)

Francisco A. Uzal, J. Glenn Songer, John F. Prescott, Michel R. Popoff (Herausgeber)

eBook Download: PDF

2016
John Wiley & Sons (Verlag)
978-1-118-72830-7 (ISBN)

Infos

Clostridial Diseases of Animals is the first book to focus on clostridial diseases in domestic and wild animals, offering a comprehensive reference on these common diseases.

• Provides a single resource for all aspects of clostridial diseases
• Presents current, comprehensive information with a focus on clinical relevance
• Covers each disease in depth, including etiology, epidemiology, clinics, gross pathology, histopathology, diagnostics, diagnostic criteria, prophylaxis, control, and treatment
• Written by the world-leading experts in the field of clostridial diseases in animals
• Offers photographs and summary tables to support the concepts discussed in the text and aid in recognition

Francisco A. Uzal, DVM, FRVC, MSc, PhD, Dipl. ACVP, is Professor of Veterinary Diagnostic Pathology at the School of Veterinary Medicine at the University of California at Davis in San Bernardino, California, USA.

J. Glenn Songer,  MA, PhD, Fellow AAM, Dipl. ACVM, is Professor (Emeritus) of Veterinary Science and Microbiology, College of Agriculture, The University of Arizona in Tucson, Arizon, USA.

John F. Prescott, MA, Vet MB, PhD, FCAHS, is Professor (Emeritus) of Veterinary Microbiology at Ontario Veterinary College, University of Guelph in Ontario, Canada.

Michel R. Popoff, DVM, PhD, is the head of the Research Unit of Anaerobic Bacteria and Toxins and the National Reference Center for Anaerobic Bacteria and Botulism at Institut Pasteur in Paris, France.

Inhalt

Title Page 5
Copyright Page 6
Contents 9
List of Contributors 13
Preface 19
SECTION 1 The Pathogenic Clostridia 21
Chapter 1 Taxonomic Relationships among the Clostridia 23
Bibliography 24
Chapter 2 General Physiological and Virulence Properties of the Pathogenic Clostridia 27
Introduction 27
Anaerobic metabolism 27
Major clostridial diseases 28
The onset of clostridial infections 29
The key role of protein toxins in clostridial disease 30
The key role of spores in the epidemiology of clostridial disease 31
Conclusions 31
Bibliography 31
Chapter 3 Brief Description of Animal Pathogenic Clostridia 33
Bibliography 39
SECTION 2 Toxins Produced by the Pathogenic Clostridia 41
Chapter 4 Toxins of Histotoxic Clostridia: Clostridium chauvoei, Clostridium septicum, Clostridium novyi, and?Clostridium sordellii 43
Introduction 43
A – Intracellularly active toxins from histotoxic clostridia 45
B – Membrane-damaging toxins from histotoxic clostridia 50
Phospholipases 62
Bibliography 62
Chapter 5 Toxins of?Clostridium perfringens 65
Introduction 65
A – Major toxins 65
B – Other toxins 71
Bibliography 76
Chapter 6 Toxins of Clostridium difficile 81
Introduction 81
Toxins A and B 81
C. difficile ADP-ribosylating toxin (CDT) 86
Hypervirulence of?C. difficile and its potential mechanisms 86
Immunotherapy of C. difficile infections 88
Conclusion 88
Bibliography 88
Chapter 7 Clostridium botulinum and Clostridium tetani neurotoxins 91
Introduction 91
Clostridia producing botulinum neurotoxins 91
Clostridium tetani 106
Susceptibility of animal species to clostridial neurotoxins 109
Structure of clostridial neurotoxins 112
Mode of action of clostridial neurotoxins 113
Concluding remarks 116
Bibliography 117
SECTION 3 Clostridial Infections of the Gastrointestinal System 127
Chapter 8 Diseases produced by Clostridium perfringens type A in mammalian species 129
Introduction 129
Yellow lamb disease 129
Other enteric diseases produced by Clostridium perfringens type A in mammals 133
Clostridium perfringens beta 2 toxin-associated gastrointestinal disease 135
Bibliography 136
Chapter 9 NetF-associated necrotizing enteritis of foals and canine hemorrhagic gastroenteritis 137
Introduction 137
Etiology 137
Epidemiology and clinical findings 138
Gross changes 140
Microscopic changes 141
Diagnosis 141
Bibliography 142
Chapter 10 Necrotic enteritis of poultry 143
Introduction 143
Epidemiology 143
Etiology and pathogenesis 144
Host response 146
Predisposing factors 146
Clinical signs 147
Gross changes 148
Microscopic changes 150
Prophylaxis 151
Diagnosis 153
Bibliography 154
Chapter 11 Infections by Clostridium perfringens type B 159
Introduction 159
Etiology 159
Clinical signs 160
Gross changes 160
Microscopic changes 161
Diagnosis 162
Prevention and treatment 162
Bibliography 162
Chapter 12 Diseases produced by Clostridium perfringens type C 163
Diseases of mammalian species 163
Necrotic enteritis of poultry 174
Bibliography 174
Chapter 13 Diseases Produced by Clostridium perfringens type D 177
Introduction 177
Etiology 178
Epidemiology and pathogenesis 178
Clinical signs 179
Gross changes 180
Microscopic changes 185
Diagnosis 189
Prophylaxis and treatment 190
Bibliography 191
Chapter 14 Infections by Clostridium perfringens type E 193
Introduction 193
Etiology 193
Pathogenesis 194
Animal disease 194
Diagnosis 195
Bibliography 195
Chapter 15 Diseases produced by Clostridium difficile 197
Introduction 197
Etiology 197
General epidemiology and pathogenesis of Clostridium difficile infection 198
Animal diseases produced by Clostridium difficile 199
Bibliography 213
Chapter 16 Disease caused by Clostridium colinum: Ulcerative enteritis of poultry and other Avian species 217
Introduction 217
Etiology 217
Epidemiology 217
Clinical signs 218
Gross changes 218
Microscopic changes 220
Diagnosis 220
Bibliography 223
Chapter 17 Clostridial Abomasitis 225
Introduction 225
Braxy (Clostridium septicum) 225
Other agents of clostridial abomasitis 228
Bibliography 239
Chapter 18 Diseases produced by Clostridium spiroforme 241
Introduction 241
Etiology 241
Pathogenesis 242
Epidemiology 243
Clinical signs 244
Gross changes 244
Microscopic changes 245
Diagnosis 245
Treatment and prophylaxis 246
Bibliography 247
SECTION 4 Clostridial Histotoxic Infections 249
Chapter 19 Blackleg 251
Introduction 251
Etiology 251
Epidemiology 252
Pathogenesis 253
Clinical signs 254
Gross changes 255
Microscopic changes 257
Diagnosis 259
Prevention and treatment 260
Bibliography 261
Chapter 20 Gas Gangrene (Malignant Edema) 263
Introduction 263
Etiology 263
Epidemiology 264
Pathogenesis 264
Clinical signs 265
Gross changes 266
Microscopic changes 270
Diagnosis 271
Treatment, control, and prophylaxis 273
Bibliography 274
Chapter 21 Gangrenous Dermatitis in Poultry 275
Introduction 275
Etiology 275
Epidemiology 276
Pathogenesis 277
Clinical signs 277
Gross changes 277
Microscopic changes 279
Diagnosis 282
Control, treatment, and prophylaxis 282
Bibliography 283
Chapter 22 Bacillary Hemoglobinuria 285
Introduction 285
Etiology 285
Epidemiology 285
Pathogenesis 286
Clinical signs 287
Gross changes 287
Microscopic changes 289
Diagnosis 292
Treatment and control 293
Bibliography 293
Chapter 23 Infectious Necrotic Hepatitis 295
Introduction 295
Etiology 295
Pathogenesis 296
Epidemiology 296
Clinical signs 296
Gross changes 297
Microscopic changes 298
Diagnosis 298
Treatment and control 298
Bibliography 298
Chapter 24 Tyzzer’s Disease 301
Introduction 301
Etiology 301
Epidemiology 302
Pathogenesis 302
Clinical signs 303
Clinico-pathologic findings 303
Gross changes 304
Microscopic changes 305
Diagnosis 310
Treatment 310
Prevention and control 310
Bibliography 311
SECTION 5 Clostridial Neurotoxic Infections 313
Chapter 25 Tetanus 315
Introduction 315
Epidemiology 315
Clinical signs 317
Gross and microscopic changes 320
Diagnosis 320
Prophylaxis, treatment, and control 320
Bibliography 321
Chapter 26 Botulism 323
Introduction 323
Etiology 323
Pathogenesis 324
Occurrence and prevalence of animal botulism 325
Epidemiology 328
Clinical signs 333
Gross and microscopic changes 336
Prophylaxis and control 336
Treatment 338
Diagnosis 338
Conclusion 344
Bibliography 344
Chapter 27 Diseases Caused by Other Clostridia Producing Neurotoxins 351
Introduction 351
Neurologic disease associated with Clostridium perfringens type D 351
Botulism caused by Clostridium baratii and?Clostridium butyricum 351
Bibliography 352
Index 353
EULA 357

Produkt-Details

• Erscheint lt. Verlag: 18.3.2016
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie
• Themenwelt: Veterinärmedizin
• Schlagworte: bovine • canine • Cat • cattle • Clostridia • clostridial disease • Clostridium • Clostridium botulinum • clostridium chauvoei • Clostridium difficile • Clostridium novyi • Clostridium perfringens • Clostridium septicum • Clostridium sordellii • Clostridium tetani • Dog • enterotoxaemic clostridia • Epidemiologie, Gesundheitswesen u. Statistik • Equine • feline • histotoxic clostridia • horse • Infections • neurotoxic clostridia • ovine • pathogenic clostridia • Pig • Ruminant • Sheep • Swine • toxins • Veterinärmedizin • Veterinärmedizin / Mikrobiologie,Parasitologie,Infektionen,Immunologie • Veterinärmedizin • Veterinärmedizin / Mikrobiologie,Parasitologie,Infektionen,Immunologie • Veterinary Epidemiology, Public Health & Statistics • Veterinary Medicine • Veterinary Microbiology, Parasitology,Infectious Diseases & Immunology
• ISBN-10: 1-118-72830-0 / 1118728300
• ISBN-13: 978-1-118-72830-7 / 9781118728307