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Design and Analysis of Vaccine Studies

M. Elizabeth Halloran, Jr. Longini Ira M., Claudio J. Struchiner (Autoren)

Buch | Hardcover

390 Seiten

2009 | 2010 ed.
Springer-Verlag New York Inc.
978-0-387-40313-7 (ISBN)

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As well as being a reference for the design, analysis, and interpretation of vaccine studies, the text covers all design and analysis stages, from vaccine development to post-licensure surveillance, presenting likelihood, frequentists, and Bayesian approaches.

and Examples.- Overview of Vaccine Effects and Study Designs.- Immunology and Early Phase Trials.- Binomial and Stochastic Transmission Models.- and Deterministic Models.- Evaluating Protective Effects of Vaccination.- Modes of Action and Time-Varying VE.- Further Evaluation of Protective Effects.- Vaccine Effects on Post-Infection Outcomes.- Household-Based Studies.- Analysis of Households in Communities.- Analysis of Independent Households.- Assessing Indirect, Total, and Overall Effects.- Randomization and Baseline Transmission.- Surrogates of Protection.

Reihe/Serie	Statistics for Biology and Health
Zusatzinfo	XVIII, 390 p.
Verlagsort	New York, NY
Sprache	englisch
Maße	160 x 240 mm
Themenwelt	Mathematik / Informatik ► Mathematik ► Wahrscheinlichkeit / Kombinatorik
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
	Studium ► Querschnittsbereiche ► Epidemiologie / Med. Biometrie
	Studium ► Querschnittsbereiche ► Infektiologie / Immunologie
	Technik ► Medizintechnik
ISBN-10	0-387-40313-2 / 0387403132
ISBN-13	978-0-387-40313-7 / 9780387403137
Zustand	Neuware