Design and Analysis of Vaccine Studies

M. Elizabeth Halloran, Jr. Longini Ira M., Claudio J. Struchiner (Autoren)

Buch | Softcover

390 Seiten

2012 | 2010 ed.
Springer-Verlag New York Inc.
978-1-4614-2488-8 (ISBN)

Artikel merken

As well as being a reference for the design, analysis, and interpretation of vaccine studies, the text covers all design and analysis stages, from vaccine development to post-licensure surveillance, presenting likelihood, frequentists, and Bayesian approaches.

and Examples.- Overview of Vaccine Effects and Study Designs.- Immunology and Early Phase Trials.- Binomial and Stochastic Transmission Models.- and Deterministic Models.- Evaluating Protective Effects of Vaccination.- Modes of Action and Time-Varying VE.- Further Evaluation of Protective Effects.- Vaccine Effects on Post-Infection Outcomes.- Household-Based Studies.- Analysis of Households in Communities.- Analysis of Independent Households.- Assessing Indirect, Total, and Overall Effects.- Randomization and Baseline Transmission.- Surrogates of Protection.

Reihe/Serie	Statistics for Biology and Health
Zusatzinfo	XVIII, 390 p.
Verlagsort	New York, NY
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Mathematik / Informatik ► Mathematik ► Wahrscheinlichkeit / Kombinatorik
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
	Studium ► Querschnittsbereiche ► Epidemiologie / Med. Biometrie
	Studium ► Querschnittsbereiche ► Infektiologie / Immunologie
	Technik ► Medizintechnik
Schlagworte	Impfung
ISBN-10	1-4614-2488-7 / 1461424887
ISBN-13	978-1-4614-2488-8 / 9781461424888
Zustand	Neuware