Co-Crystals in Pharmaceutical Sciences (eBook)
400 Seiten
Wiley-Scrivener (Verlag)
978-1-394-30249-9 (ISBN)
The book is essential for anyone in the pharmaceutical field, as it offers invaluable insights into the innovative world of cocrystals, their design principles, experimental techniques, and practical applications that can significantly enhance drug development and address critical industry challenges.
Co-Crystals in Pharmaceutical Sciences: Design to Applications is a comprehensive exploration of pharmaceutical cocrystals that introduces their scope and potential impact on drug development. This volume highlights the structural characteristics influencing cocrystals and delves into design principles and molecular interactions. Focus is placed on the advantages and challenges of integrating in-silico techniques for screening, which accelerates cocrystal discovery. Detailed coverage of experimental techniques, validation, and process optimization provides a solid foundation for readers. The book uniquely explores herbal and drug-drug cocrystals, showcasing synergies between traditional herbal medicine and modern pharmaceuticals. Scaling up cocrystal synthesis and potential commercial opportunities are examined in depth. Chapters on pharmaceutical applications emphasize how cocrystals address solubility, stability, and therapeutic challenges, with real-world examples illustrating their impact. The role of cocrystals in enhancing mechanical properties for more efficient formulations is discussed, and insights into the patent landscape and regulatory considerations round out the book, making it an indispensable resource for researchers and industry professionals alike.
Audience
Botanists, biologists, pharmaceutical professionals, drug delivery experts, and materials scientists studying pharmaceutical sciences.
Inderbir Singh, PhD, is a professor and the Assistant Dean of Research at Chitkara College of Pharmacy, Chitkara University, India. He has published eight books, 25 book chapters, and 180 papers in peer-reviewed journals. He also has 11 utility patents and 15 design registrations under review and has been granted three patents. His research interests include gastroretentive drug delivery systems, biopolymers, biomaterials, modified polymers in drug delivery, pharmaceutical cocrystals, the SeDeM expert system, and 3D printing technology.
Subrata Mallick, PhD, is a professor and the Head of the Department of Pharmaceutics in the School of Pharmaceutical Sciences, Siksha 'O' Anusandhan University, Odisha, India, with 26 years of teaching, research, and industry experience. He has published over 100 papers in international journals, six books, over 130 conference abstract proceedings, and five scientific articles, in addition to serving as an editorial board member for several international journals. His areas of interest include transdermal drug delivery systems, transmucosal drug delivery systems, powder compaction, drug degradation kinetics and stabilization, and drug-drug and drug-excipient interactions.
Ritu Rathi, PhD, is a PhD research scholar at Chitkara College of Pharmacy, Chitkara University, India, with five years of research experience in the field of pharmaceutical sciences. In addition to her active pharmaceutical research, she has published 17 articles and book chapters in various national and international journals, applied for three utility patents, and been granted two design registrations. Her research interests include pharmaceutical cocrystals, solubility enhancement techniques, herbal bioactives, and in-silico modeling techniques.
The book is essential for anyone in the pharmaceutical field, as it offers invaluable insights into the innovative world of cocrystals, their design principles, experimental techniques, and practical applications that can significantly enhance drug development and address critical industry challenges. Co-Crystals in Pharmaceutical Sciences: Design to Applications is a comprehensive exploration of pharmaceutical cocrystals that introduces their scope and potential impact on drug development. This volume highlights the structural characteristics influencing cocrystals and delves into design principles and molecular interactions. Focus is placed on the advantages and challenges of integrating in-silico techniques for screening, which accelerates cocrystal discovery. Detailed coverage of experimental techniques, validation, and process optimization provides a solid foundation for readers. The book uniquely explores herbal and drug-drug cocrystals, showcasing synergies between traditional herbal medicine and modern pharmaceuticals. Scaling up cocrystal synthesis and potential commercial opportunities are examined in depth. Chapters on pharmaceutical applications emphasize how cocrystals address solubility, stability, and therapeutic challenges, with real-world examples illustrating their impact. The role of cocrystals in enhancing mechanical properties for more efficient formulations is discussed, and insights into the patent landscape and regulatory considerations round out the book, making it an indispensable resource for researchers and industry professionals alike. Audience Botanists, biologists, pharmaceutical professionals, drug delivery experts, and materials scientists studying pharmaceutical sciences.
| Erscheint lt. Verlag | 20.3.2025 |
|---|---|
| Sprache | englisch |
| Themenwelt | Naturwissenschaften ► Chemie |
| Schlagworte | co-crystals • Co-Crystals Characterization • crystallization • Dissolution • Drug-Drug Co-Crystals • Herbal Co-Crystals • hot melt extrusion • hygroscopicity • regulatory aspects • Solubility enhancement • Solvent-Based Co-Crystallizations • Solvent evaporation • Solvent-Free Co-Crystallization • Spring and Parachute Mechanism • stability |
| ISBN-10 | 1-394-30249-5 / 1394302495 |
| ISBN-13 | 978-1-394-30249-9 / 9781394302499 |
| Informationen gemäß Produktsicherheitsverordnung (GPSR) | |
| Haben Sie eine Frage zum Produkt? |
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