Reviews of Physiology, Biochemistry and Pharmacology

Buch | Hardcover

V, 227 Seiten

2002 | 2002
Springer Berlin (Verlag)
9783540428145 (ISBN)

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In this volume of Reviews there are three outstanding articles, one on phspholipase D, an enzyme that is widely distributed in bacteria, protozoa, fungi, plants and animals. Phospholipase D carries out a transphosphatidylation reaction, which is unique to this enzyme. This review is focussed on mammalian PLDs. The second review deals with endotoxin tolerance, the term which describes the phenomenon that immune responses and metabolic changes are mitigated after repeated LPS administration. The third article summarizes the current knowledge relevant to understanding the molecular basis of GPCR function and focusses on the underlying mechanisms of GPCR malfunctions responsible for diferent human diseases.

Phospholipase D -- structure, regulation and function.-Endotoxin tolerance -- mechanisms and beneficial effects in bacterial infection.-The structural basis of G-protein-coupled receptor function and dysfunction in human disease.

Erscheint lt. Verlag	14.2.2002
Reihe/Serie	Reviews of Physiology, Biochemistry and Pharmacology ; 144
Co-Autor	J.H. Exton, M.D. Lehner, T. Hartung, T. Schöneberg, A. Schulz, T. Gudermann
Zusatzinfo	V, 227 p. 41 illus., 12 illus. in color.
Verlagsort	Berlin
Sprache	englisch
Maße	155 x 235 mm
Gewicht	450 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
	Studium ► 1. Studienabschnitt (Vorklinik) ► Physiologie
	Naturwissenschaften ► Biologie ► Biochemie
Schlagworte	Bacteria • biochemistry • Endotoxin • Enzyme • enzymes • GPCR • G-protein-coupled receptors • Hardcover, Softcover / Medizin/Nichtklinische Fächer • HC/Medizin/Klinische Fächer • HC/Medizin/Nichtklinische Fächer • immune response • LPS • membrane receptor • pharmacology • phospholipase • Physiology • PLD • Protein • receptor • Research • transmembrane receptors • transphosphatidylation reaction
ISBN-13	9783540428145 / 9783540428145
Zustand	Neuware