Reviews of Physiology, Biochemistry and Pharmacology
Seiten
2007
Springer Berlin (Hersteller)
9783540455349 (ISBN)
Springer Berlin (Hersteller)
9783540455349 (ISBN)
In this volume of Reviews there are three outstanding articles, one on phspholipase D, an enzyme that is widely distributed in bacteria, protozoa, fungi, plants and animals. Phospholipase D carries out a transphosphatidylation reaction, which is unique to this enzyme. This review is focussed on mammalian PLDs. The second review deals with endotoxin tolerance, the term which describes the phenomenon that immune responses and metabolic changes are mitigated after repeated LPS administration. The third article summarizes the current knowledge relevant to understanding the molecular basis of GPCR function and focusses on the underlying mechanisms of GPCR malfunctions responsible for diferent human diseases.
Phospholipase D—Structure, regulation and function.- Endotoxin tolerance — Mechanisms and beneficial effects in bacterial infection.- The structural basis of g-protein-coupled receptor function and dysfunction in human diseases.
| Erscheint lt. Verlag | 11.12.2007 |
|---|---|
| Reihe/Serie | Biomedical and Life Sciences |
| Biomedical and Life Sciences (R0) | Reviews of Physiology, Biochemistry and Pharmacology |
| Co-Autor | J.H. Exton, M.D. Lehner, T. Hartung, T. Schöneberg, A. Schulz, T. Gudermann |
| Zusatzinfo | V, 227 p. 41 illus., 12 illus. in color. |
| Verlagsort | Berlin |
| Sprache | englisch |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie |
| Studium ► 1. Studienabschnitt (Vorklinik) ► Physiologie | |
| Naturwissenschaften ► Biologie ► Biochemie | |
| Schlagworte | Bacteria • biochemistry • Endotoxin • Enzyme • enzymes • GPCR • G-protein-coupled receptors • immune response • LPS • membrane receptor • pharmacology • phospholipase • Physiology • PLD • Protein • receptor • Research • transmembrane receptors • transphosphatidylation reaction |
| ISBN-13 | 9783540455349 / 9783540455349 |
| Zustand | Neuware |
| Informationen gemäß Produktsicherheitsverordnung (GPSR) | |
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