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MALDI-TOF and Tandem MS for Clinical Microbiology (eBook)

eBook Download: EPUB
2017
John Wiley & Sons (Verlag)
9781118960233 (ISBN)

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This book highlights the triumph of MALDI-TOF mass spectrometry over the past decade and provides insight into new and expanding technologies through a comprehensive range of short chapters that enable the reader to gauge their current status and how they may progress over the next decade.  This book serves as a platform to consolidate current strengths of the technology and highlight new frontiers in tandem MS/MS that are likely to eventually supersede MALDI-TOF MS. Chapters discuss:
Challenges of Identifying Mycobacterium to the Species level
Identification of Bacteroides and Other Clinically Relevant Anaerobes
Identification of Species in Mixed Microbial Populations
Detection of Resistance Mechanisms
Proteomics as a biomarker discovery and validation platform
Determination of Antimicrobial Resistance using Tandem Mass Spectrometry



Haroun N. Shah                   Department of Natural Sciences, Middlesex University, London, UK

Saheer E. Gharbia              Genomic Research, Public Health England, London, UK


This book highlights the triumph of MALDI-TOF mass spectrometry over the past decade and provides insight into new and expanding technologies through a comprehensive range of short chapters that enable the reader to gauge their current status and how they may progress over the next decade. This book serves as a platform to consolidate current strengths of the technology and highlight new frontiers in tandem MS/MS that are likely to eventually supersede MALDI-TOF MS. Chapters discuss:Challenges of Identifying Mycobacterium to the Species level Identification of Bacteroides and Other Clinically Relevant AnaerobesIdentification of Species in Mixed Microbial PopulationsDetection of Resistance MechanismsProteomics as a biomarker discovery and validation platformDetermination of Antimicrobial Resistance using Tandem Mass Spectrometry

EDITORS Haroun N. Shah, Department of Natural Sciences, Middlesex University, London, UK Saheer E. Gharbia, Genomic Research, Public Health England, London, UK

List of Contributors


Mariann Ábrók
Institute of Clinical Microbiology Faculty of Medicine
University of Szeged
Hungary

Nadia Ahmod
Proteomics Research
Public Health England
London
UK

David J. Allen
Virology
Public Health England
London
UK

Jean Armengaud
CEA‐Marcoule, DSV/IBITEC‐S/SPI/Li2D
Laboratory “Innovative Technologies for Detection and Diagnostics”
Bagnols‐sur‐Cèze
France

Maud Arsac
bioMérieux SA
Marcy‐l’Etoile
France

Peter S. Borriello
Veterinary Medicines Directorate
Surrey
UK

Fredrik Boulund
Department of Mathematical Sciences
Chalmers University of Technology
Gothenburg
Sweden

Patrick Broyer
bioMérieux SA
Marcy‐l’Etoile
France

Irene Burckhardt
Division of Medical Microbiology and Hygiene, Department of Infectious Diseases
University Hospital Heidelberg
Germany

Valeria Calvaresi
Structural Mass Spectrometry and Proteomics Unit
Institut Pasteur
Paris,
France

Timothy Chambers
Proteomics Research
Public Health England
London
UK

Julia Chamot‐Rooke
Structural Mass Spectrometry and Proteomics Unit
Institut Pasteur
Paris
France

Marie‐Hélène Charles
bioMérieux SA
Marcy‐l’Etoile
France

Sonia Chatellier
bioMérieux SA
La Balme‐les‐Grottes
France

Caroline H. Chilton
Leeds Institute for Biomedical and Clinical Sciences
University of Leeds
UK

Song Lin Chua
Singapore Centre for
Environmental Life Sciences Engineering (SCELSE)
and
Lee Kong Chian School of Medicine
Nanyang Technological UniversitySingapore

Arnaldo Colombo
Department of Medicine Infectious Diseases Section
Federal University of São Paulo (UNIFESP)
SP
Brazil

Renata Culak
Proteomics Research
Public Health England
London
UK

Ronald R. Cutler
School of Biological and Chemical Sciences
Queen Mary University of London
UK

Katrien De Bruyne
Applied Maths NV
Sint‐Martens Latem
Belgium

Willem M. de Vos
Faculty of Veterinary Medicine
University of Helsinki
Finland
and
Laboratory of Microbiology
Wageningen University
The Netherlands

Itaru Dekio
Medical Centre East
Tokyo Women’s Medical University
Japan

Magalie Duchateau
Structural Mass Spectrometry and Proteomics Unit
Institut Pasteur
Paris
France

Mathieu Dupré
Structural Mass Spectrometry and Proteomics Unit
Institut Pasteur
Paris
France

Min Fang
Proteomics Research
Public Health England
London
UK

Mark A. Fisher
University of Utah School of Medicine
and
Bacteriology and Antimicrobials
ARUP Infectious Diseases Laboratory
Salt Lake City, UT, USA

Elaine Francisco
Department of Medicine Infectious Diseases Section
Federal University of São Paulo (UNIFESP)
SP
Brazil

Joseph Gault
Structural Mass Spectrometry and Proteomics Unit
Institut Pasteur
Paris
France

Tom Gaulton
Proteomics Research
Public Health England
London
UK

Saheer E. Gharbia
Genomic Research Unit
Public Health England
London
UK

Victoria Girard
bioMérieux SA
La Balme‐les‐Grottes
France

Lucia Gonzales‐Siles
Department of Infectious Diseases
Institute of Biomedicine
The Sahlgrenska Academy
University of Gothenburg
Sweden

Gilbert Greub
Institute of Microbiology, University
Hospital Center, and University of
Lausanne
Switzerland

Nicola Hennessy
Genomic Research Unit
Public Health England
London
UK

Jenny Ho
ThermoFisher Scientific
Hemel Hempstead
Hertfordshire
UK

Christiane Honisch
Illumina, Inc.
San Diego, CA
USA

Martin Hornshaw
ThermoFisher Scientific
Hemel Hempstead
Hertfordshire
UK

Jay Hyman
bioMérieux Inc
Durham, NC
USA

Axel Karger
Friedrich‐Loeffler‐Institut
Federal Research Institute for Animal Health
Greifswald – Insel Riems
Germany

Anders Karlsson
Nanoxis Consulting AB
Gothenburg
Sweden

Roger Karlsson
Department of Clinical Microbiology
Sahlgrenska University Hospital
and
Nanoxis Consulting AB
Gothenburg
Sweden

Jae‐Seok Kim
Department of Laboratory Medicine
Hallym University College of Medicine
Seoul
Korea

Yangsun Kim
ASTA Inc
Gyeonggi‐do
Korea

Carolin Kolmeder
Faculty of Veterinary Medicine
University of Helsinki
Finland

Markus Kostrzewa
Bruker Daltonik GmbH
Bremen
Germany

Annika Kotovuori
ThermoFisher Scientific
Vantaa
Finland

Erik Kristiansson
Department of Mathematical Sciences
Chalmers University of Technology
Gothenburg
Sweden

Kaarina Lähteenmäki
Finnish Red Cross Blood Service
Helsinki
Finland

Diogo B. Lima
Structural Mass Spectrometry and Proteomics Unit
Institut Pasteur
Paris
France

Nelson Lima
CEB‐Centre of Biological Engineering
Micoteca da Universidade do Minho
University of Minho
Braga
Portugal

Åsa Lindgren
Department of Clinical Microbiology
Sahlgrenska University Hospital
and
Department of Infectious Diseases
Institute of Biomedicine, The Sahlgrenska
Academy, University of Gothenburg
Sweden

Pierre Mahé
bioMérieux SA
Marcy‐l’Etoile
France

Thomas Maier
Bruker Daltonik GmbH
Bremen
Germany

Christian Malosse
Structural Mass Spectrometry and Proteomics Unit
Institut Pasteur
Paris
France

Jaana Mättö
Finnish Red Cross Blood Service
Helsinki
Finland

Mariana Mazza
Department of Mycology
INEI/Instituto Nacional de Enfermedades
Infecciosas “Dr. Carlos G. Malbrán”‐ANLIS.
Ciudad Autónoma de Buenos Aires
Argentina

Raju V. Misra
Genomic Research Unit
Public Health England
London
UK

Hermine V. Mkrtchyan
School of Biological and Chemical Sciences
Queen Mary University of London
UK

Edward R.B. Moore
Department of Clinical Microbiology
Sahlgrenska University Hospital
and
Department of Infectious Diseases
Institute of Biomedicine
The Sahlgrenska Academy
University of Gothenburg
Sweden

Leonardo P. Munoz
Department of Natural Sciences
Middlesex University
London,
UK

Elisabeth Nagy
Institute of Clinical Microbiology Faculty of Medicine
University of Szeged
Hungary

Ali Olkun
Department of Natural Sciences
Middlesex University
London,
UK

Onya Opota
Institute of Microbiology, University
Hospital Center, and University of
Lausanne
Switzerland

Ana Carolina B. Padovan
Department of Medicine Infectious Diseases Section
Federal University of São Paulo (UNIFESP)
SP
Brazil

Nadine Perrot
bioMérieux SA
La Balme‐les‐Grottes
France

Bruno Pot
Applied Maths NV
Sint‐Martens Latem
Belgium

Ian R. Poxton
Department of Medical Microbiology
University of Edinburgh
UK

Guy Prod’hom
Institute of Microbiology, University
Hospital Center, and University of
Lausanne
Switzerland

Christopher Ring
Department of Natural Sciences
Middlesex University
London,
UK

Ilja Ritamo
ThermoFisher Scientific
Vantaa
Finland

Graham Rose
Genomic Research Unit
Public Health England
London
UK

Cledir R. Santos
Department of Chemical Sciences
and Natural Resources
CIBAMA, BIOREN, University of La Frontera
Temuco
Chile

Vlad Serafim
Department of Natural Sciences
Middlesex University
London
UK

Ajit J. Shah
Department of Natural Sciences
Middlesex University
London
UK

Haroun N. Shah
Proteomics Research
Public...

Erscheint lt. Verlag 31.3.2017
Sprache englisch
Themenwelt Medizin / Pharmazie Gesundheitsfachberufe
Medizin / Pharmazie Medizinische Fachgebiete Mikrobiologie / Infektologie / Reisemedizin
Naturwissenschaften Chemie Analytische Chemie
Technik
Schlagworte antibiotic resistance of single isolates • antibiotic resistance testing • Antimicrobial Resistance • antimycotic resistance testing • bacterial identification • Biomarker discovery • biomedical scientists • Biowissenschaften • Chemie • Chemistry • Clinical Diagnostic Microbiology • clinical microbiologists • clinical microbiology • detection of antibiotic resistance • detection of biological warfare agents • Detection of Resistance Mechanisms • diagnostic technologists • epidemiological studies • identification of Bacteroides • identification of microorganisms • Identification of Species in Mixed Microbial Populations • identifying Mycobacterium • identify microbes to the species level • Klinische Mikrobiologie • Life Sciences • MALDI technology • MALDI-TOF • MALDI-TOF mass spectrometry • MALDI-ToF MS • Massenspektrometrie • mass spectral database • Mass Spectrometry • Medical Science • Medizin • Microbial DNA Analysis • Microbial Identification • microbial pathogenicity • Mikrobiologie • pathogen detection • Proteogenomics of Non-Model Microorganisms • Proteomics • single strain typing • strain typing • Tandem Mass Spectrometry • tandem MS/MS • top-down proteomics
ISBN-13 9781118960233 / 9781118960233
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