Microneedle-mediated Transdermal and Intradermal Drug Delivery (eBook)

Ryan F. Donnelly, Thakur Raghu Raj Singh, Desmond I. J. Morrow, A. David Woolfson (Autoren)

eBook Download: EPUB

2012
John Wiley & Sons (Verlag)
978-1-119-95966-3 (ISBN)

Infos

One of the latest techniques in drug delivery, microneedles are used for administering a wide range of drug substances used to treat various medical conditions. Thorough background information is included providing a history of the field. Various methods used to produce micorneedles are described as well as a snapshot of the future directions within the industry. Written by highly qualified authors, this new text is the only title providing a comprehensive review of microneedle research in the fields of transdermal and intradermal drug delivery.

Ryan F. Donnelly, Senior Lecturer in Pharmaceutics, School of Pharmacy, Queen's University Belfast, UK

Thakur Raghu Raj Singh, Lecturer in Pharmaceutics, School of Pharmacy, Queen's University Belfast, UK

Desmond I.J. Morrow, Honorary Research Fellow, School of Pharmacy, Queen's University Belfast, UK

A. David Woolfson, Chair in Pharmaceutics and Head of the School  of Pharmacy, Queen’s University Belfast, UK

---

Microneedles can be used for delivery of a wide range of drug substances for practically any medical condition and present a real opportunity for vaccines and medicines that are unsuitable for oral administration or conventional patch delivery. Microneedle-mediated Transdermal and Intradermal Drug Delivery covers the major aspects relating to the use of microneedle arrays in enhancing drug delivery applications. It provides an overview of the various methods employed to design and produce microneedles, from the different materials involved to the importance of application methods. It carefully and critically reviews ongoing transdermal and intradermal delivery research using microneedles and includes the outcomes of in vivo animal and human studies. Importantly, it also discusses the safety and patient acceptability studies carried out to date. Finally, the book reviews the recent patents in microneedle research and describes the ongoing developments within industry that will determine the future of microneedle-mediated transdermal and intradermal drug delivery. By an expert author team with practical experience in the design and development of drug delivery systems this is the only text that provides a comprehensive review of microneedle research in transdermal and intradermal drug delivery.

Inhalt

Preface.

About the Authors.

1 Transdermal Drug Delivery.

2 Microneedles: Design, Microfabrication and Optimization.

3 Microneedle Applicator Designs for Transdermal Drug Delivery Applications.

4 Transdermal Delivery Applications.

5 Microneedle-mediated Intradermal Delivery.

6 Clinical Application and Safety Studies of Microneedles.

7 Microneedles: Current Status and Future Perspectives.

Index.

Produkt-Details

• Erscheint lt. Verlag: 17.1.2012
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
• Schlagworte: application • Arrays • Aspects • Clinical Pharmacology & Therapeutics • Condition • Delivery • Drug • drug substances • Enhancing • Klinische Pharmakologie • Klinische Pharmakologie u. Therapie • Major • Medical • Medical Science • Medizin • Methods • Microneedle • microneedlemediated transdermal • Microneedles • Overview • Pharmacology & Pharmaceutical Medicine • Pharmakologie u. Pharmazeutische Medizin • present • Produce • Range • use • various • wide
• ISBN-10: 1-119-95966-7 / 1119959667
• ISBN-13: 978-1-119-95966-3 / 9781119959663