Microneedle-mediated Transdermal and Intradermal Drug Delivery (eBook)

Ryan F. Donnelly, Thakur Raghu Raj Singh, Desmond I. J. Morrow, A. David Woolfson (Autoren)

eBook Download: PDF

2012
John Wiley & Sons (Verlag)
978-1-119-95965-6 (ISBN)

Infos

Microneedles can be used for delivery of a wide range of drug
substances for practically any medical condition and present a real
opportunity for vaccines and medicines that are unsuitable for oral
administration or conventional patch delivery.

Microneedle-mediated Transdermal and Intradermal Drug
Delivery covers the major aspects relating to the use of
microneedle arrays in enhancing drug delivery applications. It
provides an overview of the various methods employed to design and
produce microneedles, from the different materials involved to the
importance of application methods. It carefully and critically
reviews ongoing transdermal and intradermal delivery research using
microneedles and includes the outcomes of in vivo animal and human
studies. Importantly, it also discusses the safety and patient
acceptability studies carried out to date. Finally, the book
reviews the recent patents in microneedle research and describes
the ongoing developments within industry that will determine the
future of microneedle-mediated transdermal and intradermal drug
delivery.

By an expert author team with practical experience in the design
and development of drug delivery systems this is the only text that
provides a comprehensive review of microneedle research in
transdermal and intradermal drug delivery.

Autor

Ryan F. Donnelly, Senior Lecturer in Pharmaceutics, School of Pharmacy, Queen's University Belfast, UK Thakur Raghu Raj Singh, Lecturer in Pharmaceutics, School of Pharmacy, Queen's University Belfast, UK Desmond I.J. Morrow, Honorary Research Fellow, School of Pharmacy, Queen's University Belfast, UK A. David Woolfson, Chair in Pharmaceutics and Head of the School of Pharmacy, Queen's University Belfast, UK

Inhalt

Preface.

About the Authors.

1 Transdermal Drug Delivery.

2 Microneedles: Design, Microfabrication and Optimization.

3 Microneedle Applicator Designs for Transdermal Drug Delivery Applications.

4 Transdermal Delivery Applications.

5 Microneedle-mediated Intradermal Delivery.

6 Clinical Application and Safety Studies of Microneedles.

7 Microneedles: Current Status and Future Perspectives.

Index.

Produkt-Details

• Erscheint lt. Verlag: 12.1.2012
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
• Schlagworte: application • Arrays • Aspects • Clinical Pharmacology & Therapeutics • Condition • Delivery • Drug • drug substances • Enhancing • Klinische Pharmakologie • Klinische Pharmakologie u. Therapie • Major • Medical • Medical Science • Medizin • Methods • Microneedle • microneedlemediated transdermal • Microneedles • Overview • Pharmacology & Pharmaceutical Medicine • Pharmakologie u. Pharmazeutische Medizin • present • Produce • Range • use • various • wide
• ISBN-10: 1-119-95965-9 / 1119959659
• ISBN-13: 978-1-119-95965-6 / 9781119959656