Biomarkers of acid-base status and their interrelationships with body fatness, glucocorticoids, and height

Yifan Hua (Autor)

Buch

128 Seiten

2022
Cuvillier Verlag
978-3-7369-7618-4 (ISBN)

Infos

Acid-base homeostasis is essential for human health and a variety of physiological conditions. Pathophysiological changes can result in acid-base derangements, which can be accompanied by acute and long-term metabolic disorders. Moreover, even a narrow change of blood pH still within the physiological change, e.g., a diet-induced shift towards a more acidic status, has been reported to already cause adverse health consequences. Against this background, we aimed to, by using non-invasive urinary biomarkers, examine acid-base-related physiological and epidemiological relationships of body fatness with 24-h urine pH, the potential mediatory roles of inflammatory biomarkers in the high body fat–low urine pH relation, and the association between 24-h urinary glucocorticoid excretion and renal citrate output, as well as the prospective relationships of protein intake and dietary acid load during childhood and adolescence with adult height. All study participants were selected and data came from the DOrtmund Nutritional and Antropometric Longitudinally Designed (DONALD) Study, which includes regular examinations on dietary intake, metabolism, and growth in healthy children and adolescents until their adulthood without particular pre-specified endpoints.

Produkt-Details

• Erscheinungsdatum: 14.05.2022
• Verlagsort: Göttingen
• Sprache: englisch
• Maße: 148 x 210 mm
• Themenwelt: Sachbuch/Ratgeber ► Gesundheit / Leben / Psychologie
• Themenwelt: Weitere Fachgebiete ► Land- / Forstwirtschaft / Fischerei
• Schlagworte: 11β-hydroxysteroid dehydrogenase type 1 • 11β-hydroxysteroid dehydrogenase type 2 • 20α-dihydrocortisol • Adult height • Age at peak height velocity • Age at take-off, Body mass index • Amino acid, Adrenocorticotropic hormone • Aminosäure, Adrenocorticotrope Hormon • Body fat percent, Body surface area • Chronic Kidney Disease • Chronisches Nierenleiden • Corticotropin-Releasing-Hormon • Corticotropin releasing hormone • Cortisol binding globulin • Dietary potential renal acid load • DONALD Studie, Fettmassenindex • DONALD Study • Erwachsenengröße • Fat mass index, Fruits and vegetables • Freies Cortisol im Urin • freisetzendes Hormon • Früchte • Gemüse • Glucocorticoide, Wachstumshormone • Glucocorticoid, Growth hormone • Growth hormone releasing hormone • Hypothalamic-pituitary-adrenal • Hypothalamus-Hypophyse-Nebennieren • Insulinähnlicher Wachstumsfaktor-1 • Insulin-like growth factor-1 • Körperfettanteil • Körperoberfläche, Transcortin • Lösliches interzelluläres Adhäsionsmolekül-1 • Low-grade metabolic acidosis • mineralocorticoid receptor • Mineralokortikoidrezeptor • Net acid excretion, Net acid excretion capacity • Niedriggradige metabolische Azidose • Organic acid, Renal tubular acidosis • Organische Säure • Potential renal acid load • Renale tubuläre Azidose • Soluble intercellular adhesion molecule-1 • Taillenumfang, 6β-hydroxycortisol • Tetrahydrocortisol • Tetrahydrocortisol, Freies Cortison im Urin • Titratable acid, Tetrahydrocortisone • Titrierfähige Säure, Tetrahydrocortison • Urinary free cortisol • Urinary free cortisone • Urinary potential renal acid load • Urinary urea nitrogen • Urin-Harnstoff-Stickstoff • Waist Circumference
• ISBN-10: 3-7369-7618-6 / 3736976186
• ISBN-13: 978-3-7369-7618-4 / 9783736976184
• Zustand: Neuware