Stem Cell-Based Regenerative Medicine in Canine Practice (eBook)

Mudasir Bashir Gugjoo (Autor)

eBook Download: EPUB

2025
962 Seiten
Wiley (Verlag)
978-1-394-25326-5 (ISBN)

Infos

A practical guide to stem cell-based regenerative techniques in dogs

Stem Cell-Based Regenerative Medicine in Canine Practice delivers an essential reference for the use of stem cells in canine practice. Intuitively organized by organ and body systems, the book is easy-to-follow, and addresses many common conditions encountered when dealing with dogs in veterinary practice, including those affecting the central nervous system, muscular system, and vascular system.

The book is grounded in evidence-based research and readers are provided with guidance on the potential challenges and problems that may arise when considering and using stem cell therapeutics. It also explains the techniques for stem cell extraction and how to use stem cell regenerative medicine for the best results.

Readers will also find:

• An introduction to the treatment of various clinical conditions like corneal ulcers and keratoconjunctivitis
• Comprehensive explorations of the treatment of osteoarthritis, bone gap defects, tendon/ligament injuries, muscle affections, peripheral nerves, periodontitis, esophageal ulcers, inflammatory bowel disease, liver, diabetes, and skin wounds
• Practical discussions of canine mesenchymal stem cell sources, properties, and regulations for clinical use
• An overview of comparative analysis between various stem cells for therapeutics
• Complimentary access to a website containing reference videos and clinical guidance

Written for veterinarians in general practice, Stem Cell-Based Regenerative Medicine in Canine Practice will also benefit veterinary students and researchers.

The Author

Mudasir Bashir Gugjoo, PhD, is a Senior Assistant Professor at the Division of Veterinary Clinical Complex, Faculty of Veterinary Sciences & Animal Husbandry of the Sher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir, India.

Textauszug

Abbreviations

18F‐FDG:

F‐fluorodeoxyglucose

2D:

2‐Dimensional

3‐D:

3 dimensional

4HNE:

4‐Hydroxynenonal

5‐Aza:

5‐Aza‐2′‐deoxycytidine

5‐HT:

Serotonin

99mTc‐MIBI:

99mTc‐sestamibi

99mTcO4−:

99mTc‐pertechnetate

ABCG2:

ATP‐binding cassette (ABC) transporters

AC:

Adenylate cyclase

ACI:

Autologous chondrocyte implantation

ACM:

Acellular matrix

ACTA2:

Actin alpha 2

AD:

Adipose tissue

ADAMTS:

Disintegrin and metalloproteinase thrombospondin‐like motifs

ADAMTS16:

ADAM metallopeptidase with thrombospondin type 1 motif 16

AF:

Anal furunculosis

AFP:

Alpha‐fetoprotein

AKI:

Acute kidney injury

AKT:

Ak strain transforming

ALB:

Albumin

ALDH1A3:

Aldehyde dehydrogenase 1A3

ALI:

Acute lung injury

ALK5:

Activin receptor‐like kinase 5

ALP:

Alkaline phosphatase

ALT:

Alanine transaminase

AM:

Amniotic membrane

AMPs:

Antimicrobial peptides

ANG:

Angiopoietin

Anpep:

Aminopeptidase N

AP:

Apical ligament

AQP1:

Aquaporin 1

ARDS:

Acute respiratory distress syndrome

ARE:

Antibiotic responsive enteropathy

AST:

Aspartate aminotransferase

AT3:

Antithrombin 3

ATF6:

Activating transcription factor 6

ATMPs:

Advanced therapy medicinal products

ATP:

Adenosine triphosphate

ATR:

Angiotensin receptor

AURKA:

Aurora‐A kinase

AV:

Atrioventricular

Bad:

Bcl‐2–associated death protein

Bax:

Bcl‐2–associated X protein

BBB:

Blood–brain barrier

BCL‐2:

B‐cell lymphoma 2

BCP:

Biphasic calcium phosphate

BC‐TS:

Tubular bacterial cellulose

BDKRB2:

Bradykinin receptor B2

BDNF:

Brain‐derived nerve factor

BDNF:

Brain‐derived neurotrophic factor

bFGF:

Basic fibroblast growth factor

BglII:

Bacillus globigii‐derived type II restriction endonuclease

BHA:

Butylated hydroxyanisole

BIC:

Bone implant contact

BM‐:

Bone marrow

BMA:

Bone marrow aspirate

BMD:

Bone mineral density

BME:

β‐Mercaptoethanol

BMP:

Bone morphogenetic factor

BrdU:

Bromodeoxyuridine

BST1:

Bone marrow stromal cell antigen‐1

BTE:

Bone tissue engineering

BUN:

Blood urea nitrogen

C/ABB:

Chitosan/anorganic bovine bone

CADESI‐4:

Canine atopic dermatitis extent severity index‐4

CAGR:

Compound annual growth rate

cAMP:

3′5‐cyclic monophosphate monohydrate

CARD15:

Caspase recruitment domain‐containing protein 15

CBC:

Complete blood count

CBPI:

Canine Brief Pain Inventory

CCAAT/EBPα:

Cytosine–cytosine–adenosine–adenosine–thymidine enhancer binding protein

CCECAI:

Canine Chronic Enteropathy Clinical Activity Index

CCL2:

C‐C motif ligand 2

CCl4:

Carbon tetrachloride

CCNB1:

Cyclin B1

CD:

Canine distemper

CD:

Cluster of differentiation

CDCs:

Cardiosphere‐derived stem cells

CdHA:

Calcium‐deficient hydroxyapatite

CDK1:

Cyclin‐dependent kinase 1

Cdkn1a:

Cyclin‐dependent kinase inhibitor 1A

CDV:

Canine distemper virus

CDX4:

Caudal Type Homeobox 4

CFU(f):

Colony forming unit(fibroblasts)

CGRP:

Calcitonin gene‐related peptide

CHF:

Congestive heart failure

CHOP:

C/EBP Homologous Protein

CIBDAI:

Clinical Inflammatory Bowel Disease Activity Index

CIE:

Chronic inflammatory enteropathy

CIMVs:

Cytochalasin B‐induced membrane vesicles

C‐jun:

Jun Proto‐Oncogene

CK19:

Cytokeratin19

CKD:

Chronic kidney disease

CLEC3A:

C‐type lectin domain family 3 member A

CM:

Conditioned medium

CMAP:

Compound muscle action potential

CMC:

Carboxy methyl cellulose

CMR:

Cardiovascular magnetic resonance

c‐MYC:

Cellular myelocytomatosis

CNS:

Central nervous system

CNTF:

Ciliary neurotrophic factor

COL2A:

Collagen 2A

COL3A1:

Collagen 3A1

Coll I:

Collagen I

COX:

Cyclooxygenase

CPB:

Cardiopulmonary bypass

CPS:

Calcium phosphate scaffold

CrCL:

Cranial cruciate ligament

CRI:

Continuous rate infusion

CRISPR:

Clustered regularly interspaced short palindromic repeats

CRP:

C‐reactive protein

CSA:

Cyclosporin A

CSF:

Cerebrospinal fluid

CSG:

Chondroitin sulphate glycosaminoglycan

CSH:

Calcium sulfate hemihydrate

CTGF:

Connective tissue growth factor

CTI:

Cardiac troponin I

CTNND2:

Catenin delta 2

CTT:

Cardiac troponin T

CVM:

Centre for veterinary medicine

Cx45:

Connexin 45

CXCR4:

C‐X‐C chemokine receptor type 4

CYP:

Cytochrome P450

DAPT:

N‐[N‐(3,5‐Difluorophenacetyl)‐L‐alanyl]‐S‐phenylglycine t‐butyl ester

dbCAMP:

Dibutyryl Cyclic Adenosine Monophosphate

DCM:

Dilatation cardiomyopathy

DCN:

Decorin

DCs:

Dendritic cells

DDFT:

Deep digital flexor tendon

DE:

Definitive endoderm

DED:

Dry eye disease

Dexa:

Dexamethasone

DFE:

Dermatophagoides farinae extract

DISA:

Dual isotope simultaneous acquisition

DKA:

Diabetic ketoacidosis

DKK1:

Dickkopf‐1

DLA:

Dog leukocyte antigen

DM:

Diabetes mellitus

DMD:

Duchenne’s muscle dystrophy

DMEM:

Dulbecco’s minimally essential medium

DMEM‐HG:

Dulbecco’s modified Eagle’s Media‐High Glucose

dMSCs:

Dog mesenchymal stem cells

DMSO:

Dimethyl sulfoxide

dMyHC:

Developmental myosin heavy chain

DNA:

Deoxyribonucleic acid

DP:

Dental pulp

DRB1:

Major Histocompatibility Complex, Class II, DR Beta 1

DTEF:

Divergent transcriptional enhancer factor

ECG:

Electrocardiography

ECM:

Extracellular matrix

ECMO:

Extracorporeal membrane oxygenation

EDNRA:

Endothelin receptors

EDVI:

End diastolic volume index

EF:

Ejection fraction

EGF:

Epidermal growth factor

EGFP:

Enhanced green fluorescent protein

Egr1:

Early response protein

ELISA:

Enzyme‐linked immunosorbent assay

EMT:

Epithelial–mesenchymal transition

eNOS:

Endothelial nitric oxide synthase

Eomes:

Eomesodermin

Epac2:

Exchange Protein Directly Activated by cAMP 2

EPCS:

Electric‐pulse current stimulation

EPCs:

Endothelial progenitor cells

EPO:

Erythropoietin

EPOR:

Erythropoietin receptor

ER:

Endoplasmic reticulum

ERK:

Extracellular signal‐regulated kinase

ESCs:

Embryonic stem cells

ESD:

Endoscopic submucosal dissection

ESF:

External skeletal fixation

ESVI:

End systolic volume index

EVs:

Extracellular vesicles

FBS:

Fetal bovine serum

FDA:

Food and Drug Administration

FDMBB:

Freeze‐dried mineral bone block

FGF:

Fibroblast growth factor

FGFR:

Fibroblast growth factor receptor 2

FGFR1:

Fibroblast growth factor 1 receptor

FISH:

Fluorescence in situ hybridization

Foxa1:

Forkhead box protein A genes

...

Produkt-Details

• Erscheint lt. Verlag: 28.5.2025
• Sprache: englisch
• Themenwelt: Veterinärmedizin
• Schlagworte: canine regenerative medicine • canine regenerative veterinary medicine • canine stem cell properties • canine stem cell regulations • Canine stem cells • canine stem cell sources • canine stem cell treatment • canine stem cell videos • veterinary stem cell
• ISBN-10: 1-394-25326-5 / 1394253265
• ISBN-13: 978-1-394-25326-5 / 9781394253265