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Biology and Diseases of the Ferret (eBook)

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2014 | 3. Auflage
852 Seiten
Wiley-Blackwell (Verlag)
978-1-118-78273-6 (ISBN)

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Biology and Diseases of the Ferret, Third Edition has been thoroughly revised and updated to provide a current, comprehensive reference on the ferret. Encyclopedic in scope, it is the only book to focus on the characteristics that make the ferret an important research animal, with detailed information on conditions, procedures, and treatments. Offering basic information on biology, husbandry, clinical medicine, and surgery, as well as unique information on the use of ferrets in biomedical research, Biology and Diseases of the Ferret is an essential resource for investigators using ferrets in the laboratory and for companion animal and comparative medicine veterinarians.

The Third Edition adds ten completely new chapters, covering regulatory considerations, black-footed ferret recovery, diseases of the cardiovascular system, viral respiratory disease research, morbillivirus research, genetic engineering, hearing and auditory function, vision and neuroplasticity research, nausea and vomiting research, and lung carcinogenesis research.  Additionally, the anesthesia, surgery, and biomethodology chapter has been subdivided into three and thoroughly expanded. The book also highlights the ferret genome project, along with the emerging technology of genetically engineered ferrets, which is of particular importance to the future of the ferret as an animal model in research and will allow the investigation of diseases and their genetic basis in a small, easily maintained, non-rodent species.



James G. Fox, DVM, MS, DACLAM, is Professor and Director at MIT's Division of Comparative Medicine, as well as Chair of ACLAM's publications committee. He is also an Adjunct Professor at Tufts University's Cummings School of Veterinary Medicine and at the University of Pennsylvania's School of Veterinary Medicine.

Robert P. Marini, DVM, DACLAM, is Assistant Director and Chief of Veterinary Surgical Resources at MIT's Division of Comparative Medicine and Lecturer in Health, Science and Technology, also at MIT.

James G. Fox, DVM, MS, DACLAM, is Professor and Director at MIT's Division of Comparative Medicine, as well as Chair of ACLAM's publications committee. He is also an Adjunct Professor at Tufts University's Cummings School of Veterinary Medicine and at the University of Pennsylvania's School of Veterinary Medicine. Robert P. Marini, DVM, DACLAM, is Assistant Director and Chief of Veterinary Surgical Resources at MIT's Division of Comparative Medicine and Lecturer in Health, Science and Technology, also at MIT.

Contributors ix

Preface xv

Section I Biology and Husbandry 3

Chapter 1 Taxonomy, History, and Use 5

James G. Fox

Chapter 2 Anatomy of the Ferret 23

Howard Evans and Nguyen Quoc An

Chapter 3 Neuroanatomy of the Ferret Brain with Focus on the
Cerebral Cortex 69

Christopher D. Kroenke, Brian D. Mills, Jaime F. Olavarria, and
Jeffrey J. Neil

Chapter 4 Physiology of the Ferret 81

Mark T. Whary

Chapter 5 Nutrition of the Ferret 123

James G. Fox, Carrie S. Schultz, and Brittany M. Vester
Boler

Chapter 6 Housing and Management 145

James G. Fox and Rosemary Broome

Chapter 7 Normal Clinical and Biological Parameters 157

James G. Fox

Chapter 8 Growth and Reproduction 187

James G. Fox, Judith A. Bell, and Rosemary Broome

Chapter 9 Regulatory Considerations 211

Robert P. Marini

Chapter 10 Recovery of the Black-Footed Ferret 219

Rachel Santymire, Heather Branvold-Faber, and Paul E.
Marinari

Section II Diseases and Clinical Applications 233

Chapter 11 Physical Examination, Preventive Medicine, and
Diagnosis in the Ferret 235

Robert P. Marini

Chapter 12 Anesthesia 259

Jeff C. Ko and Robert P. Marini

Chapter 13 Surgery 285

Stephen J. Mehler

Chapter 14 Diseases of the Hematopoietic System 311

Jörg Mayer, Susan E. Erdman, and James G. Fox

Chapter 15 Diseases of the Genitourinary System 335

James G. Fox and Judith A. Bell

Chapter 16 Diseases of the Gastrointestinal System 363

Kirk J. Maurer and James G. Fox

Chapter 17 Diseases of the Endocrine System 377

Cassandra L. Miller, Robert P. Marini, and James G. Fox

Chapter 18 Diseases of the Cardiovascular System 401

Robert A. Wagner

Chapter 19 Other Systemic Diseases 421

James G. Fox

Chapter 20 Viral Diseases of Ferrets 439

Matti Kiupel and David Perpiñán

Chapter 21 Bacterial and Mycoplasmal Diseases 519

Alton G. Swennes and James G. Fox

Chapter 22 Parasitic Diseases 553

Mary M. Patterson, James G. Fox, and Mark L. Eberhard

Chapter 23 Mycotic Diseases 573

James G. Fox

Chapter 24 Neoplastic Diseases 587

James G. Fox, Sureshkumar Muthupalani, Matti Kiupel, and Bruce
Williams

Section III Research and Applications 627

Chapter 25 The Ferret in Viral Respiratory Disease Research
629

Deborah R. Taylor

Chapter 26 The Ferret in Morbillivirus Research 641

Veronika von Messling

Chapter 27 Use of the Ferret in Cardiovascular Research
653

James P. Morgan

Chapter 28 Genetic Engineering in the Ferret 665

Xingshen Sun, Ziying Yan, Xiaoming Liu, Alicia K. Olivier, and
John F. Engelhardt

Chapter 29 Hearing and Auditory Function in Ferrets 685

Fernando R. Nodal and Andrew J. King

Chapter 30 The Ferret as a Model for Visual System Development
and Plasticity 711

Jitendra Sharma and Mriganka Sur

Chapter 31 The Ferret in Nausea and Vomiting Research: Lessons
in Translation of Basic Science to the Clinic 735

Nathalie Percie du Sert and Paul L.R. Andrews

Chapter 32 The Ferret in Lung Carcinogenesis and Nutritional
Chemoprevention Research 779

Xiang-Dong Wang and Chun Liu

Index 795

"This edition is well indexed and referenced and is a
great practice reference." (JAVMA, 15 December
2014)

"There are many color photos in this edition, with a
strong emphasis on histopathology. This book stands alone as a
complete and comprehensive book on ferrets, and a new edition after
16 years is certainly justified."
(Doody's, 9 January 2015)

"In conclusion, The Biology and the Diseases of the
Ferret, 3rd edition is a valuable resource because of
the breadth and scope of information covered. Members of the
private practice and laboratory animal communities will find it a
useful addition to their libraries." (Laboratory
Animal Practitioner, 1 October 2014)

Contributors


Nguyen Quoc An, DVM, MS

College of Veterinary Medicine

University of Georgia

Athens, GA

 

Paul L.R. Andrews, PhD

Emeritus Professor of Comparative Physiology

Division of Biomedical Sciences

St George's University of London

London, UK

 

Judith A. Bell, DVM, PhD

Ontario Veterinary College

University of Guelph

Guelph, Ontario, Canada

 

Heather Branvold-Faber, MS, DVM

Wellington, CO

 

Rosemary Broome, DVM, MPVM

Associate Director

MedImmune LLC

Mountain View, CA

 

Mark L. Eberhard, PhD

Director

CGH Division of Parasitic Diseases and Malaria

Centers for Disease Control and Prevention

Atlanta, GA

 

John F. Engelhardt, PhD

Professor

Department of Anatomy and Cell Biology

College of Medicine

University of Iowa

Iowa City, IA

 

Susan E. Erdman, DVM, MPH, DACLAM

Assistant Director and Principal Research Scientist

Division of Comparative Medicine

Massachusetts Institute of Technology

Cambridge, MA

 

Howard Evans, PhD

Professor Emeritus of Veterinary and Comparative Anatomy

Veterinary College

Cornell University

Ithaca, NY

 

James G. Fox, DVM, MS, DACLAM

Professor and Director

Division of Comparative Medicine

Massachusetts Institute of Technology

Cambridge, MA

 

Andrew J. King, PhD

Professor of Neurophysiology

Department of Physiology

Anatomy and Genetics

University of Oxford

Oxford, UK

 

Matti Kiupel, MVSc, PhD

Associate Professor

Department of Pathobiology and Diagnostic Investigation

Michigan State University

Lansing, MI

 

Jeff C. Ko, DVM, MS, DACVA

Professor

Department of Anesthesiology

Purdue University College of Veterinary Medicine

West Lafayette, IN

 

Christopher D. Kroenke, PhD

Advanced Imaging Research Center

Oregon National Primate Research Center

Oregon Health and Science University

Portland, OR

 

Chun Liu, MD, MS/MPH

Jean Mayer USDA Human Nutrition Research Center on Aging

Tufts University

Boston, MA

 

Xiaoming Liu, PhD

Department of Anatomy and Cell Biology

University of Iowa

Iowa City, IA

 

Paul E. Marinari, MS

Senior Curator

Center for Species Survival

Smithsonian Conservation Biology Institute

National Zoological Park

Front Royal, VA

 

Robert P. Marini, DVM, DACLAM

Assistant Director, Chief

Veterinary Surgical Resources

Division of Comparative Medicine

Massachusetts Institute of Technology

Cambridge, MA

 

Kirk J. Maurer, DVM, PhD, DACLAM

Associate Director and Attending Veterinarian

Center for Comparative Medicine and Research

Dartmouth College

Lebanon, NH

 

Jörg Mayer, DVM, MS

President of the Association of Exotic Mammal Veterinarians

Associate Professor of Zoological Medicine

College of Veterinary Medicine

University of Georgia

Athens, GA

 

Stephen J. Mehler, DVM, Diplomate ACVS

Hope Veterinary Specialists

Malvern, PA

 

Cassandra L. Miller, DVM

Division of Comparative Medicine

Massachusetts Institute of Technology

Cambridge, MA

 

Brian D. Mills, MS (PhD student in Behavioral Neuroscience)

Oregon Health and Science University

Portland, OR

 

James P. Morgan, PhD

Professor of Medicine

Tufts University School of Medicine

Service Chief

Cardiology

Steward Carney Hospital

Dorchester, MA

 

Sureshkumar Muthupalani, BVSc, PhD, DACVP

Comparative Pathologist

Division of Comparative Medicine

Massachusetts Institute of Technology

Cambridge, MA

 

Jeffrey J. Neil, MD, PhD

Professor of Neurology, Pediatrics, Radiology, and Anatomy and Neurobiology

Department of Neurology

Washington University School of Medicine

St. Louis, MO

 

Fernando R. Nodal, PhD

Department of Physiology

Anatomy and Genetics

University of Oxford

Oxford, UK

 

Jaime F. Olavarria, MD, PhD

Associate Professor

Department of Psychology

University of Washington

Seattle, WA

 

Alicia K. Olivier, DVM, PhD, DACVP

Department of Pathology

University of Iowa

Iowa City, IA

 

Mary M. Patterson, MS, DVM, DACLAM

Clinical Veterinarian, Chief of Primate Resources

Division of Comparative Medicine

Massachusetts Institute of Technology

Cambridge, MA

 

Nathalie Percie du Sert, PhD

Programme Manager

National Centre for the Replacement, Refinement and Reduction of Animals in Research

London, UK

 

David Perpiñán, LV, MSc, Dip ECZM (Herpetology)

Zoological Veterinary Specialist

Hospital for Small Animals

Royal (Dick) School of Veterinary Studies

The University of Edinburgh

Midlothian, UK

 

Rachel Santymire, MS, PhD

Director

Davee Center for Epidemiology and Endocrinology

Lincoln Park Zoo

Chicago, IL

 

Carrie S. Schultz, PhD

Nutritionist

Land O’Lakes Purina Feed LLC

St. Louis, MO

 

Jitendra Sharma, PhD

Research Scientist

Picower Institute for Learning and Memory

Massachusetts Institute of Technology

Assistant Neuroscientist

A.A. Martinos Center for Biomedical Imaging

Instructor

Department of Radiology

Massachusetts General Hospital

Boston, MA

 

Xingshen Sun, PhD

Associate Research Scientist/Engineer

Department of Anatomy and Cell Biology

University of Iowa

Iowa City, IA

 

Mriganka Sur, PhD

Paul E. and Lilah Newton Professor of Neuroscience

Picower Institute for Learning and Memory

Director

Simons Center for the Social Brain

Department of Brain and Cognitive Sciences

Massachusetts Institute of Technology

Cambridge, MA

 

Alton G. Swennes, MS, DVM

Clinical Veterinarian

Center for Comparative Medicine

Baylor College of Medicine

Houston, TX

 

Deborah R. Taylor, PhD

Laboratory of Emerging Pathogens

Division of Emerging and Transfusion-Transmitted Diseases

Office of Blood Research and Review

CBER FDA

Bethesda, MD

 

Brittany M. Vester Boler, MS, PhD

Nutritionist

Land O’Lakes Purina Feed LLC

St. Louis, MO

 

Veronika von Messling, Dr. Med. Vet.

Director

Division of Veterinary Medicine

Paul-Erlich Institute

Federal Institute for Vaccines and Biomedicines

Langen, Germany

Associate Professor

EID Program

Duke-NUS Graduate Medical School

Singapore

 

Robert A. Wagner, VMD, Diplomat ACVP-ECM

Division of Laboratory Animal Resources

University of Pittsburgh

Pittsburgh, PA

 

Xiang-Dong Wang, MD, PhD

Director and Senior Scientist

Nutrition and Cancer Biology Laboratory

Jean Mayer USDA Human Nutrition Research Center on Aging

Tufts University

Boston, MA

 

Mark T. Whary, DVM, PhD, DACLAM

Associate Director

Division of Comparative Medicine

Massachusetts Institute of Technology

Cambridge, MA

 

Bruce Williams, DVM, DACVP

Senior Pathologist

Veterinary Pathology Service

Joint Pathology Center

Rockville, MD

 

Ziying Yan, PhD

Department of Anatomy and Cell Biology

University of Iowa

Iowa City, IA

Content Reviewers


Roberta Scipioni Ball, DVM, MS, DACLAM

Marshall BioResources

North Rose, NY

 

Dean E. Biggins, PhD

Research Wildlife Biologist

U.S. Geological Survey (BRD)

Fort Collins Science Center

Fort Collins, CO

 

Catherine M. Brown, DVM, MSc, MPH

State Public Health Veterinarian

Massachusetts Department of Public Health

Hinton State Laboratory Institute

Jamaica Plain, MA

 

Edward J. Dubovi, PhD

Professor and Director

Virology Laboratory

Animal...

Erscheint lt. Verlag 26.3.2014
Sprache englisch
Themenwelt Medizin / Pharmazie
Veterinärmedizin Klinische Fächer
Veterinärmedizin Kleintier
Schlagworte Frettchen • Laboratory Animal Medicine • Veterinär-Labormedizin • Veterinärmedizin • Veterinärmedizin / Exoten • Veterinärmedizin / Mikrobiologie,Parasitologie,Infektionen,Immunologie • Veterinär-Labormedizin • Veterinärmedizin • Veterinärmedizin / Exoten • Veterinärmedizin / Mikrobiologie,Parasitologie,Infektionen,Immunologie • Veterinary Medicine • Veterinary Medicine - Exotic Pets • Veterinary Microbiology, Parasitology,Infectious Diseases & Immunology
ISBN-10 1-118-78273-9 / 1118782739
ISBN-13 978-1-118-78273-6 / 9781118782736
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