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Molecular Diagnostics - Lela Buckingham

Molecular Diagnostics

Fundamentals, Methods, and Clinical Applications

(Autor)

Buch | Softcover
504 Seiten
2026 | Fourth Edition
F.A. Davis Company (Verlag)
978-1-7196-5113-4 (ISBN)
CHF 136,15 inkl. MwSt
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This Book Taught Me Everything. “This book gave me my foundation in biochemistry lab diagnostics. I 100% recommend this book to anyone who wants to learn about the different procedures…like (nucleic acid purification, nucleic acid amplification, expression testing, etc...)”—Ana, Online Reviewer

Good book for CLS/MLT students.“Loved this book, I had the previous editions for college for my CLS/MTL classes. The book explains a lot and in great detail. Bought it again because I rented the other one and wanted a hard copy to study for the board.”—A.Y.Z.C., Online Reviewer

Build the foundation for classroom and professional success.

Meet the challenges of this rapidly expanding field with a solid understanding of the fundamentals of nucleic acid biochemistry as well as the advanced concepts integral to practice in today’s laboratories. With a focus on the application of molecular concepts to the diagnosis of disease, this popular resource encompasses microbiology, virology, genetics, oncology, and human identification.

Inside, you’ll find in-depth explanations of the principles of molecular-based assays as well as reference material and trouble-shooting tips for the laboratory. Discussions of general diagnostic procedures prepare you to adapt to the emergence of new diagnostic technologies.



New, Updated & Expanded! Incorporating advances in science and clinical practice and newer technologies and techniques
New! Expanded descriptions of human identification for application to parentage testing, chimerism analysis, ancestry testing, and genetic genealogy
Updated & Expanded! Coverage of basic genetics and DNA, proteins, cell function, managing and analyzing DNA data, next generation sequencing, polymerase chain reaction, primer designs, and more.
New! Streamlined organization and a full-color design and art program to make often challenging concepts and techniques easier to understand
New & Updated! Critical-Thinking Case Studies and Lab Exercises online
Coverage of the application of molecular diagnostics to the clinical laboratory encompasses microbiology, virology, genetics, oncology, and human identification.
“Advanced Concepts” challenge those interested in a higher level of learning.
“Case Studies” in the clinical chapters show students how to apply molecular concepts to diagnostic testing.
Study Questions at the end of each chapter (with answers in the Appendix) mirror the ASCP certification exam’s style.

College of Health Sciences, Rush University Medical Center, Chicago, IL

Section I Fundamentals of Molecular Biology
Chapter 1: Nucleic Acids
Chapter 2: Genotype to Phenotype
Chapter 3: Gene Expression and Epigenetics
Section II Common Techniques in Molecular Biology
Chapter 4: Collection, Isolation and Quantification of Nucleic Acids
Chapter 5: Resolution and Detection of Nucleic Acids
Chapter 6: Analysis and Characterization of Nucleic Acids and Proteins
Chapter 7: Nucleic Acid Amplification
Chapter 8: Human Chromosomal Structure and Structural Variants
Chapter 9: Targeted Variant Detection
Chapter 10: Molecular Sequencing
Section III Molecular Techniques in the Clinical Laboratory
Chapter 11: Molecular Variants and Human Identification
Chapter 12: Detection and Identification of Microorganisms
Chapter 13: Molecular Detection of Inherited Diseases
Chapter 14: Molecular Oncology
Chapter 15: DNA-Based Tissue Typing
Chapter 16: Quality Assurance and Quality Control in the Molecular Laboratory
Appendix A: Study Question Answers 
Appendix B: Answers to Case Studies 
Glossary 
Index 

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