Biomimetic Lipid Membranes: Fundamentals, Applications, and Commercialization

Fatma N. Kök, Ahu Arslan Yildiz, Fatih Inci (Herausgeber)

Buch | Hardcover

XXIX, 306 Seiten

2019
Springer International Publishing (Verlag)
978-3-030-11595-1 (ISBN)

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This book compiles the fundamentals, applications and viable product strategies of biomimetic lipid membranes into a single, comprehensive source. It broadens its perspective to interdisciplinary realms incorporating medicine, biology, physics, chemistry, materials science, as well as engineering and pharmacy at large. The book guides readers from membrane structure and models to biophysical chemistry and functionalization of membrane surfaces. It then takes the reader through a myriad of surface-sensitive techniques before delving into cutting-edge applications that could help inspire new research directions. With more than half the world's drugs and various toxins targeting these crucial structures, the book addresses a topic of major importance in the field of medicine, particularly biosensor design, diagnostic tool development, vaccine formulation, micro/nano-array systems, and drug screening/development.

Provides fundamental knowledge on biomimeticlipid membranes;
Addresses some of biomimetic membrane types, preparation methods, properties and characterization techniques;
Explains state-of-art technological developments that incorporate microfluidic systems, array technologies, lab-on-a-chip-tools, biosensing, and bioprinting techniques;
Describes the integration of biomimetic membranes with current top-notch tools and platforms;
Examines applications in medicine, pharmaceutical industry, and environmental monitoring.

Dr. Fatma Nese KÖK is currently Associated Professor in the Molecular Biology and Genetics Department of Istanbul Technical University, Turkey. She graduated from the Chemical Engineering Department at the Middle East Technical University and received her M.Sc. and Ph.D degrees from Biotechnology Program at the same University in 1997 and 2001, respectively. After receiving a postdoctoral research fellowship from the Alexander von Humboldt Foundation, she spent 2.5 years in Germany, in a joint project of Max Planck Institute (MPI) for Polymer Research (Mainz) and MPI for Biochemistry (Martinstred) (2002-2005) working on artificial lipid membranes. Her research interests include biomaterials and tissue engineering scaffold design, biosensors, controlled release systems, and construction and characterization of artificial lipid bilayers.

Chapter1: Structural and mechanical characterization of supported model membranes by AFM.- Chapter2: To image the orientation and spatial distribution of reconstituted Na+,K+-ATPase in model lipid membranes.- Chapter3: Asymmetric Model Membranes: Frontiers and Challenges.- Chapter4: Modelling of Cell Membrane Systems.- Chapter5: Molecular Dynamics Studies of Nanoparticle Transport Through Model Lipid Membranes.- Chapter6: Investigation of Cell Interactions on Biomimetic Lipid Membranes.- Chapter7: Tethered lipid membranes as platforms for biophysical studies and advanced biosensors.- Chapter8: Biomedical Applications: Liposomes and Supported Lipid Bilayers for Diagnostics, Theranostics, Imaging, Vaccine Formulation, and Tissue Engineering.- Chapter9: Lipid Bilayers and Liposomes on Microfluidics Realm: Techniques and Applications.- Chapter10: Biomimetic Model Membranes as Drug Screening Platforms.- Chapter11: Biomimetic Membranes as an Emerging Water Filtration Technology.- Chapter12: Applications of lipid membranes based biosensors for the rapid detection of food toxicants and environmental pollutants.

Erscheinungsdatum	04.05.2019
Zusatzinfo	XXIX, 306 p. 89 illus., 87 illus. in color.
Verlagsort	Cham
Sprache	englisch
Maße	155 x 235 mm
Gewicht	661 g
Themenwelt	Technik ► Maschinenbau
Schlagworte	biochemical engineering • Biomedical Applications • Biomimetic Membranes for Sensor • biomimetic membranes for water purification • Biomimetic Models • biosensing applications • Diagnostics • Lipid membranes • Membrane biophysics • membrane dynamics • microfluidics • Surface Chemistry • Surface sensing techniques
ISBN-10	3-030-11595-X / 303011595X
ISBN-13	978-3-030-11595-1 / 9783030115951
Zustand	Neuware