Integrated Microfabricated Biodevices

Advanced Technologies for Genomics, Drug Discovery, Bioanalysis, and Clinical Diagnostics

Michael J. Heller, Andras Guttman (Herausgeber)

Buch | Hardcover

464 Seiten

2002
Crc Press Inc (Verlag)
978-0-8247-0606-7 (ISBN)

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Discusses integrated micro fabricated devices such as DNA chips, lab-on-a-chip, micro capillary electrophoresis systems, biosensors, and micro analytical systems. This book reveals how to reach predetermined locations with proteins and orient molecules while preserving their bioactivity.

This book discusses the new generation of integrated microfabricated devices, including DNA chips, Lab-on-a-Chip, microcapillary electrophoresis systems, biosensors, and microanalytical systems. It traces their development with the established and evolving technologies such as microlithography, micromachining, microelectromechanical systems, microfluids, and nanotechnology.

Michael J. Heller, Andras Guttman

Towards integrated electrophoretic microdevice for clinical diagnostics; creating a lab-on-a-chip with microfluidic technologies; Short Tandem Repeat (STR) analysis on microfabricated electrophoretic devices; basic sample preparation - DNA separation and purification; multiplex integrated online sample preparation for DNA sequencing and genetic typing; interfacing capillaries to microseparation devices for sample introduction; electric field meditated separation of DNA fragments on planar gel microchips; development of battery powered, portable instrumentation for rapid PCR analysis; practical aspects of sheath flow fraction collection in CE; microelectric array systems for DNA diagnostic and pharmacogenomic applications; the flowthru chip - a miniature, three-dimensional biochip platform; DNA arrays on plastic devices; microfluidic devices fabricated by polymer hot embossing; microfabricated reactor technology; approaches toward miniaturization of high throughput screening of chemical libraries; integrated microsystems in clinical chemistry - constraints and consequences.

Verlagsort	Bosa Roca
Sprache	englisch
Maße	210 x 280 mm
Gewicht	725 g
Themenwelt	Medizin / Pharmazie ► Physiotherapie / Ergotherapie ► Orthopädie
	Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
	Naturwissenschaften ► Chemie ► Physikalische Chemie
	Technik ► Medizintechnik
	Technik ► Umwelttechnik / Biotechnologie
ISBN-10	0-8247-0606-4 / 0824706064
ISBN-13	978-0-8247-0606-7 / 9780824706067
Zustand	Neuware