An Information Technology Framework for Predictive, Preventive and Personalised Medicine

A Use-Case with Hepatocellular Carcinoma

Leonard Berliner, Heinz U. Lemke (Herausgeber)

Buch | Softcover

XX, 130 Seiten

2016
Springer International Publishing (Verlag)
978-3-319-38434-4 (ISBN)

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This book explores how PPPM, clinical practice, and basic research could be best served by information technology (IT). A use-case was developed for hepatocellular carcinoma (HCC). The subject was approached with four interrelated tasks: (1) review of clinical practices relating to HCC; (2) propose an IT system relating to HCC, including clinical decision support and research needs; (3) determine how a clinical liver cancer center can contribute; and, (4) examine the enhancements and impact that the first three tasks will have on the management of HCC. An IT System for Personalized Medicine (ITS-PM) for HCC will provide the means to identify and determine the relative value of the wide number of variables, including clinical assessment of the patient -- functional status, liver function, degree of cirrhosis, and comorbidities; tumor biology, at a molecular, genetic and anatomic level; tumor burden and individual patient response; medical and operative treatments and their outcomes.

Preface.- Introduction.- The Digital Patient Model and Model Guided Therapy.- Hepatocellular Carcinoma and Patient Assessment.- Imaging in Hepatocellular Carcinoma: Radiologic Assessment.- Imaging in Hepatocellular Carcinoma: PET/CT.- Personalized Chemotherapy for Hepatocellular Carcinoma.- Surgical Treatment for Hepatocellular Carcinoma.- Minimally Invasive Therapies for Hepatocellular Cancer: Ablation Technologies.- Chapter 9 Minimally Invasive Therapies for Hepatocellular Cancer: Ablation Therapies.- Minimally Invasive Therapies for Hepatocellular Cancer:Catheter-Directed Therapies.- Radiation Oncology in the Treatment of Hepatocellular Carcinoma.- Design of an IT System for Hepatocellular Carcinoma.- Outlook and Expert Recommendations for Predictive, Preventive and Personalized Medicine and Hepatocellular Carcinoma.

Erscheinungsdatum	20.10.2016
Reihe/Serie	Advances in Predictive, Preventive and Personalised Medicine
Zusatzinfo	XX, 130 p. 23 illus., 15 illus. in color.
Verlagsort	Cham
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Medizin / Pharmazie
Themenwelt	Technik ► Medizintechnik
Schlagworte	3D graphics and modelling • Data Mining • data mining and knowledge discovery • Decision support system • Expert systems / knowledge-based systems • Health Informatics • Hepatocellular Cancer • hepatology • Information Technology • Information technology: general issues • Medical equipment and techniques • Medicine • Medicine: general issues • Model Guided Therapy • Oncology • Predictive, Preventive and Personalised Medicine • Simulation and modeling
ISBN-10	3-319-38434-1 / 3319384341
ISBN-13	978-3-319-38434-4 / 9783319384344
Zustand	Neuware