Adhesive Interactions of Mussel Foot Proteins

Jing Yu (Autor)

Buch | Softcover

XVI, 65 Seiten

2016
Springer International Publishing (Verlag)
978-3-319-38340-8 (ISBN)

Artikel merken

Water and moisture undermine strong adhesion to polar surfaces. Marine mussels, however, achieve durable underwater adhesion using a suite of proteins that are peculiar in having high levels of 3, 4-dihydroxyphenylalanine (Dopa). Mussel adhesion has inspired numerous studies on developing the next generation of wet adhesives. This thesis presents recent progress in understanding the basic surface and intermolecular interactions employed by mussels to achieve strong and durable wet adhesion. The surface forces apparatus (SFA) and various other techniques were applied to measure the interactions between mussel foot protein-3 fast (Mfp-3 fast ) and the model substrate, mica, as well as the interactions between various mussel adhesive proteins. The results in this thesis show that Dopa plays an essential role in mussel adhesion and that mussels delicately control the interfacial redox environment to achieve strong and durable Dopa mediated adhesion. The interplay between Dopa and hydrophobic interactions is also evident in mussel adhesion.

Dr. Yu grew up in Hangzhou, a beautiful city in eastern China. He received his B.Sc. in Chemical Engineering from Tsinghua University, China and his PhD in Chemical Engineering from University of California, Santa Barbara. Dr. Yu fell in love with the great sunshine and beach of the University of California, Santa Barbara campus during his 5 years PhD where he worked in Professor Jacob Israelachvili's group. Yu conducted and pioneered outstanding research in many important areas including the wet adhesion of marine mussel adhesive proteins. Yu's work has been recognized by multiple international journals and online media sources including Nature, Chemical Biology, ABC Science and the Faculty of 100. Yu is currently a postdoctoral scholar in the Chemistry and Chemical Engineering Division at California Institute of Technology.

Mussel adhesion.- Surface Interactions in Biological Systems.- Effects of interfacial redox in mussel adhesive protein films on mica.- Antioxidant is a Key Factor in Mussel Protein Adhesion.- Hydrophobic enhancement of Dopa-mediated adhesion in a mussel foot protein.- Learning from the pieces: the adhesion of mussel-inspired peptides.

Erscheinungsdatum	20.08.2016
Reihe/Serie	Springer Theses
Zusatzinfo	XVI, 65 p. 31 illus., 24 illus. in color.
Verlagsort	Cham
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Technik ► Umwelttechnik / Biotechnologie
Schlagworte	biochemical engineering • biomaterials • biomedical engineering • Biotechnology • Chemistry and Materials Science • Materials Science • Mfps • Mica • Mussel Foot Proteins • Surface chemistry and adsorption • Surface Forces Apparatus • Surface Interactions • Surfaces and Interfaces, Thin Films
ISBN-10	3-319-38340-X / 331938340X
ISBN-13	978-3-319-38340-8 / 9783319383408
Zustand	Neuware