Drug-device Combinations for Chronic Diseases (eBook)

Suping Lyu, Ronald Siegel (Autoren)

eBook Download: PDF

2015 | 1. Auflage
280 Seiten
John Wiley & Sons (Verlag)
978-1-119-00300-7 (ISBN)

Infos

This book covers two areas, the first detailing the concepts and technologies of drug-device combination products. The second area includes case studies of important products that either significantly shape our technologies and thinking, or contribute to current healthcare practice.
The book:

* Discusses where drugs and devices work, where they fail, and when they need to work with each other

* Reviews interactions between human bodies and the drug-device combination products the measurements of these interactions

* Covers how a drug-device combination product is developed, tested, and regulated

* Includes case studies of steroid releasing leads, AOA treated tissue heart valves, intrathecal drug delivery pumps, infuse bone grafts, drug eluting stents, and antimicrobial meshes

Autor

SuPing Lyu, PhD, joined, is a Principal Scientist at Medtronic, Inc., and his research focuses?on drug-device combination products, biomaterials, and biomaterial-biological interactions. He is a visiting professor of the Minnesota Center for Industrial Mathematics, School of Mathematics at University of Minnesota?and has?been a guest lecturer of biomaterials for the?university since 2006. In addition to authoring over 25 peer-reviewed papers, Dr. Lyu?served as an associate editor for the IEEE/EMBC 2009 conference. Ronald A. Siegel, ScD, is Professor of Pharmaceutics and Biomedical Engineering at the University of Minnesota.?He is also Program Director of the Biomaterials and Pharmaceutical Materials program of Industrial Partners for Research in Interfacial and Materials Engineering.?Professor Siegel has published over 100 papers primarily on hydrogels, drug delivery devices, microsensors, and mathematical modelling of transport. He has received several research and best paper awards from both CRS and AAPS.

Inhalt

FOREWORD vii

PREFACE ix

PART I BACKGROUNDS 1

1 Addressing Medical Device Challenges with Drug-Device Combinations 3

2 Historical Survey of Drug Delivery Devices 39

3 Development of Combination Product Drug Delivery Systems 66

4 Drug-Material Interactions, Materials Selection, and Manufacturing Methods 89

PART II PRODUCTS 117

5 Steroid-Releasing Lead 119

6 Thromboresistant Vascular Graft 142

7 Device-Enabled Drug Infusion Therapies 182

8 Promus Element Plus®: A Drug-Eluting Stent 214

9 Infuse® Bone Graft 241

INDEX 261

Produkt-Details

• Erscheint lt. Verlag: 4.11.2015
• Reihe/Serie: Wiley-Society for Biomaterials
• Reihe/Serie: Wiley-Society for Biomaterials
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Gesundheitsfachberufe
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete
• Themenwelt: Technik ► Maschinenbau
• Themenwelt: Technik ► Umwelttechnik / Biotechnologie
• Schlagworte: Biomaterial • Biomaterialien • biomaterials • biomedical engineering • Biomedizintechnik • Chemie • Chemistry • Chronische Krankheit • Drug Formulation & Delivery • Molecular Bioengineering • Molekulares Bioengineering • Wirkstoffformulierung, Wirkstofftransport • Wirkstofffreisetzung
• ISBN-10: 1-119-00300-8 / 1119003008
• ISBN-13: 978-1-119-00300-7 / 9781119003007