Recombinant Poxviruses

Matthew M. Binns, Geoffrey L. Smith (Autoren)

Buch | Hardcover

368 Seiten

1992
Crc Press Inc (Verlag)
978-0-8493-6179-1 (ISBN)

Titel z.Zt. nicht lieferbar
Versandkostenfrei
Auch auf Rechnung

Artikel merken

Recombinant Poxviruses provides a comprehensive examination of poxviruses with an emphasis on the potential of these viruses as new vaccines. The book considers a wide range of issues involved in producing new genetically engineered live vaccines, such as efficacy, safety, stability, cost, host range, immune response, immunization route, use of multivalent vaccines, and need for revaccination. The opening chapter describes the origin of vaccinia virus, its use to eradicate smallpox, and the pathogenesis of poxvirus infections. Subsequent chapters examine the molecular biology of poxviruses, methods of constructing vaccinia virus recombinants, and applications; the use and immune responses induced by poxvirus recombinants as live vaccines; and the important issues of the safety and immunogenicity of vaccinia virus. The book's final two chapters report the progress that has been made developing avipoxviruses and parapoxviruses as candidate recombinant vaccines.

Recombinant Poxviruses will be a welcome addition to the bookshelves of virologists, microbiologists, infectious disease specialists, and veterinarians.

Matthew M. Binns, Geoffrey L. Smith

Vaccinia Virus as a Vaccine and Poxvirus Pathogenesis (F. Fenner). Molecular Biology of Poxviruses (B. Moss). The Design, Construction, and Use of Vaccinia Virus Recombinants (M. Mackett and G.L. Smith). Poxvirus Recombinants as Live Vaccines (W.I. Cox, J. Tartaglia, and E. Paoletti). Development and Deliberate Release of a Vaccinia-Rabies Recombinant Virus for the Oral Vaccination of Foxes Against Rabies (P.-P. Pastoret, B. Brochier, J. Blancou, M. Artois, M. Aubert, M.-P. Kieny, J.-P. Lecocq, B. Languet, G. Chappuis, and P. Desmettre). Immunogenicity and Antigen Presentation (M.E. Andrew, B.E.H. Coupar, and D.B. Boyle). Safety and Attenuation of Vaccinia Virus (R.M.L. Buller and G.J. Palumbo). Avipoxvirus Vectors (M.E.G. Boursnell). Parapoxviruses: Their Biology and Potential as Recombinant Vaccines (A.J. Robinson and D.J. Lyttle).

Erscheint lt. Verlag	27.5.1992
Zusatzinfo	45 Tables, black and white; 8 Halftones, black and white
Verlagsort	Bosa Roca
Sprache	englisch
Maße	156 x 234 mm
Gewicht	725 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Mikrobiologie / Infektologie / Reisemedizin
	Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie
	Technik ► Umwelttechnik / Biotechnologie
ISBN-10	0-8493-6179-6 / 0849361796
ISBN-13	978-0-8493-6179-1 / 9780849361791
Zustand	Neuware