Fluorinated Heterocyclic Compounds (eBook)

Synthesis, Chemistry, and Applications

Viacheslav A. Petrov (Autor)

eBook Download: PDF

2009
John Wiley & Sons (Verlag)
9780470528945 (ISBN)

Infos

A thorough survey of synthetic methods, chemistry, and applications of major classes of fluorinated heterocycles Merging organic, heterocyclic, and fluoroorganic chemistry, fluorinated heterocyclic compounds have distinctively desirable properties suitable for use in pharmaceuticals and agrichemicals, especially their ability to penetrate the cell membrane barrier for drug absorption. Offering a needed overview of this relatively new addition to the heterocyclic family, this essential reference provides the latest state-of-the-art information on key application areas within fluorine chemistry. With contributions from experts from both industry and academia, the book covers the chemistry, synthesis, and applications of fluorinated heterocycles with chapters on: Three-, four-, five-, six-, and seven-membered fluorine-containing heterocycles Fluorinated nucleosides Fluorointermediates Applications of fluorinated heterocycles in agricultural products Pharmaceuticals containing fluorinated heterocycles Technical applications of fluorinated heterocycles Written by a team of world-recognized experts in the area of organic and industrial chemistry of fluorine, Fluorinated Heterocyclic Compounds: Synthesis, Chemistry, and Applications will prove valuable to both students and researchers from academia and industry seeking further knowledge of the synthetic methods, chemistry, and applications of major classes of fluorinated heterocycles.

Autor

Viacheslav A. Petrov is a Research Fellow with DuPont Central Research and Development in Wilmington, Delaware.

Inhalt

PREFACE.

CONTRIBUTORS.

INTRODUCTION: NOMENCLATURE OF POLYFLUORINATED
HETEROCYCLES.

PART I SYNTHESIS AND CHEMISTRY OF FLUORINATED
HETEROCYCLES.

1 Fluorinated Three-Membered Ring Heterocycles (David
M. Lemal and Sudharsanam Ramanathan).

2 Fluorinated Four-Membered Heterocycles (Roman B. Larichev
and Viacheslav A. Petrov).

3 Fluorinated Five-Membered Nitrogen-Containing Heterocycles
(Kenneth L. Kirk).

4 Fluorinated Five-Membered Heterocycles Containing Oxygen,
Sulfur, Selenium, and Phosphorus (Yuriy Shermolovich).

5 Synthesis of Fluorinated Sugars from Fluorine-Containing
Synthons (Xiao-Long Qiu and Feng-Ling Qing).

6 Synthesis of Ring-Fluorinated Pyridines (Anatoliy M.
Shestopalov, Alexander A. Shestopalov, Lyudmila A. Rodinovskaya,
and Anna V. Gromova).

7 Synthesis and Chemical Transformation of Six-Membered Aromatic
Heterocycles Containing Perfluoroalkyl Groups (Viacheslav A.
Petrov).

8 Perfluorinated Six-Membered Aromatic Heterocycles Containing
One or More Heteroatom (Graham Sandford).

9 Perfluorinated Nonaromatic Heterocycles (Viacheslav A.
Petrov).

10 Seven-Membered and Larger Ring-Fluorinated Heterocycles
(Viacheslav A. Petrov).

PART II APPLICATION OF FLUORINATED HETEROCYCLIC
MATERIALS.

11 Agricultural Products Based on Fluorinated Heterocyclic
Compounds (Wonpyo Hong).

12 Pharmaceuticals Containing Fluorinated Heterocyclic Compounds
(Kenji Uneyama and Kenji Sasaki).

13 Practical Uses of Fluorinated Heterocycles (Paul R.
Resnick).

Index.

Rezensionen

"The book is well referenced and indexed and covers the literature
from pioneering work in the 1960s to recent developments up to
2009. It provides an excellent source of information on fluorinated
heterocycles as well as something to dip into if you are looking
for some unexpected and stimulating chemistry. The book is suitable
for advanced undergraduates and research students and represents a
valuable addition to the literature that should be on the shelves
of libraries in both academic and industrial institutions. I would
recommend this book to all scientists who consider working with
fluorinated compounds-be they synthetic chemists, life-science
chemists, or materials scientists." (Angewandte Chemie,
2010)

"A wealth of information on the types of fluorinated heterocycles
that are possible and their methods of synthesis, reactivity, and
utilization. Having worked in fluorine chemistry and with selected
heterocyclic compounds for more than 45 years, I found many
familiar examples but also much new material." (Journal of the
American Chemical Society, 2010)

Produkt-Details

• Erscheint lt. Verlag: 4.11.2009
• Sprache: englisch
• Themenwelt: Naturwissenschaften ► Chemie ► Organische Chemie
• Themenwelt: Technik
• Schlagworte: Ability • Absorption • Agriculture • Applications • barrier • Cell • Chemie • Chemistry • compounds • crops • desirable • distinctively • Drug • Family • Feldfrüchte • Feldfrüchte • Fluorinated • Heterocycles • heterocyclic • Heterocyclische Verbindungen • Landwirtschaft • Major • Membrane • Methods • organic • Organic Chemistry • Organische Chemie • Pharmaceutical & Medicinal Chemistry • pharmaceuticals • Pharmazeutische u. Medizinische Chemie • properties suitable • Synthetic • thorough survey • use
• ISBN-13: 9780470528945 / 9780470528945