Binding and Dissociation Kinetics for Different Biosensor Applications Using Fractals (eBook)

Ajit Sadana (Autor)

eBook Download: EPUB

2006 | 1. Auflage
384 Seiten
Elsevier Science (Verlag)
978-0-08-046369-8 (ISBN)

Infos

The application of biosensors is expanding in different areas. These are portable and convenient devices that permit the rapid, accurate, and reliable detection of analytes of interest present either in the atmosphere or in aqueous or in liquid phases. The detection of glucose levels in blood for the effective management of diabetes is one. Though different biosensors have been designed for an increasing number of applications, the kinetics of binding (and dissociation) of analytes by the receptors on the biosensor surfaces has not been given enough attention in the open literature. This is a very important area of investigation since it significantly impacts biosensor performance parameters such as stability, sensitivity, selectivity, response time, regenerability, etc. Binding and Dissociation Kinetics for Different Biosensor Applications Using Fractals addresses this critical need besides helping to correct or demonstrate the need to modify the present software available with commercial biosensors that determines the kinetics of analyte-receptor reactions on biosensor surfaces.
* first book to provide detailed kinetic analysis of the binding and dissociation reactions that are occuring on the biosensor surface
* addresses the area of analyte-receptor binding and dissociation kinetics occurring on biosensor surfaces
* provides physical insights into reactions occuring on biosensor surfaces

Inhalt

Cover 1
Binding and Dissociation Kinetics for Different Biosensor Applications Using Fractals 4
Copyright page 5
Foreword 8
Preface 10
Contents 12
Chapter 1. Introduction 16
1.1 Definition of Biosensors 16
1.2 Current and Future Applications 19
1.3 Biosensor Economics 24
1.4 Overview 25
References 27
Chapter 2. Modeling and Theory 32
2.1 Introduction 32
2.2 Theory 35
References 43
Chapter 3. Fractal Analysis of Toxin and Pathogen Detection on Biosensor Surfaces 46
3.1 Introduction 46
3.2 Theory 47
3.3 Results 49
3.4 Conclusions 67
References 69
Chapter 4. Fractal Binding and Dissociation Kinetics of Heart-Related Compounds on Biosensor Surfaces 72
4.1 Introduction 72
4.2 Theory 73
4.3 Results 75
4.4 Conclusions 104
References 105
Chapter 5. Fractal Analysis of Binding and Dissociation Kinetics and Interactions of Cancer Markers on Biosensor Surfaces 108
5.1 Introduction 108
5.2 Theory 109
5.3 Results 111
5.4 Conclusions 123
References 124
Chapter 6. Fractal Analysis of Binding and Dissociation of Autoimmune Disease Markers on Biosensor Surfaces 126
6.1 Introduction 126
6.2 Theory 127
6.3 Results 129
6.4 Conclusions 148
References 150
Chapter 7. Fractal Binding and Dissociation Kinetics of Prion Proteins on Biosensor Surfaces 152
7.1 Introduction 152
7.2 Theory 153
7.3 Results 155
7.4 Conclusions 173
References 174
Chapter 8. Detection of Environmental Contaminants by Biosensors 176
8.1 Introduction 176
8.2 Theory 179
8.3 Results 181
8.4 Conclusions 208
References 209
Chapter 9. Fractal Analysis of Proteins Involved in Drug Design on Biosensor Surfaces 214
9.1 Introduction 214
9.2 Theory 215
9.3 Results 217
9.4 Conclusions 230
References 232
Chapter 10. Sol–Gel Biosensor Applications 234
10.1 Introduction 234
10.2 Theory 235
10.3 Results 237
10.4 Conclusions 253
References 255
Chapter 11. Novel Biosensing Methods 258
11.1 Introduction 258
11.2 Theory 259
11.3 Results 261
11.4 Conclusions 285
References 286
Chapter 12. Fractal Analysis of the Binding and Dissociation of Different Compounds on Biosensor Surfaces 288
12.1 Introduction 288
12.2 Theory 289
12.3 Results 291
12.4 Conclusions 329
References 331
Chapter 13. Market Size and Economics for Biosensors 334
13.1 Introduction 334
13.2 Biosensor Trends and Collaborations between Companies and State and Governmental Agencies 339
13.3 Commercial Development of Biosensors 341
13.4 Biosensor Technologies and Techniques 342
13.5 Examples of Small and Medium Biosensor Companies that are either Successful or are on the way to be Successful 346
13.6 Factors that could help Increase Biosensor Markets 350
13.7 Examples of Size of Grants and Financing from Different Sources 351
13.8 Conclusions 353
References 354
Index 358

Produkt-Details

• Erscheint lt. Verlag: 8.8.2006
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie
• Themenwelt: Naturwissenschaften ► Biologie
• Themenwelt: Naturwissenschaften ► Chemie ► Analytische Chemie
• Themenwelt: Technik ► Medizintechnik
• Themenwelt: Technik ► Umwelttechnik / Biotechnologie
• ISBN-10: 0-08-046369-X / 008046369X
• ISBN-13: 978-0-08-046369-8 / 9780080463698