Sex Determination and Sexual Development (eBook)

Mark Van Doren (Herausgeber)

eBook Download: EPUB

2009 | 1. Auflage
304 Seiten
Elsevier Science (Verlag)
978-0-08-092284-3 (ISBN)

Infos

This volume reviews our current understanding for how sex determination is initiated and how it results in sexual dimorphic development. Chapters discussing work on different model systems provide a basis for understanding similarities that exist between different species. Coverage includes discussion of sexual development of the soma in C. elegans, sexual development of the germline in C. elegans, sexual development of the soma in Drosophila, sexual development of the germline in Drosophila, sexual development of the soma in the mouse, sexual development of the germline in the mouse, control of sex-specific behavior in Drosophila, and control of sex-specific behavior in vertebrates.

* Uncovers the latest research findings on sexual determination and sexual development
* Detailed model systems illustrate species differences and similarities
* Thoroughly explains sexual development across various germlines including Drosophila
* Outlines the origins and control of sex-specific behavior

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This volume reviews our current understanding for how sex determination is initiated and how it results in sexual dimorphic development. Chapters discussing work on different model systems provide a basis for understanding similarities that exist between different species. Coverage includes discussion of sexual development of the soma in C. elegans; sexual development of the germline in C. elegans; sexual development of the soma in Drosophila; sexual development of the germline in Drosophila; sexual development of the soma in the mouse; sexual development of the germline in the mouse; control of sex-specific behavior in Drosophila; and control of sex-specific behavior in vertebrates. - Uncovers the latest research findings on sexual determination and sexual development- Model systems illustrate key sexual similarities- Explores in-depth the origins of sex specific behavior

Inhalt

Front Cover 1
Current Topics in Developmental Biology: Sex Determination and Sexual Development 4
Copyright Page 5
Contents 6
Contributors 10
Preface 12
Chapter 1: Somatic Sexual Differentiation in Caenorhabditis Elegans 14
1. Background 15
2. Telling One from Two: The Primary Signal 17
3. The Global Sex Regulatory Pathway 18
4. Attaining Sexual Dimorphism 23
5. The Interface Between Sex Determination and Sex Differentiation 39
6. Something Old, Something New: Conservation of Nematode Sexual Regulators 42
7. The Future 43
Acknowledgments 43
References 44
Chapter 2: Sex Determination in the Caenorhabditis elegans Germ Line 54
1. Nematode Gender: Hermaphrodites, Females, and Males 55
2. The Core Sex-Determination Pathway 57
3. Transcriptional Control of Germ Cell Fates by TRA-1 60
4. Modulating the Sex-Determination Pathway to Create Hermaphrodites 63
5. Maintaining a Balance Between TRA-2 and FEM-3 Levels 66
6. Do FOG-1 Levels Control Germ Cell Fates? 68
7. Mysteries 68
8. Conclusion 71
Acknowledgments 72
References 72
Chapter 3: The Creation of Sexual Dimorphism in the Drosophila Soma 78
1. Sex Determination 79
2. The Creation of Sexual Dimorphism 87
3. A New Look at an Old Problem 106
References 109
Chapter 4: Drosophila Germline Sex Determination: Integration of Germline Autonomous Cues and Somatic Signals 122
1. Introduction 123
2. Sexually Dimorphic Niches Regulate Germ Cells 123
3. Sex Determination in the Germ Cells 135
4. Germ Cells in a Sex-Mismatched Soma 141
5. Concluding Remarks 155
Acknowledgments 156
References 156
Chapter 5: Sexual Development of the Soma in the Mouse 164
1. History of Sex Determination in Mammals 165
2. Molecular Control of Sex Determination 172
3. Secondary Sex Differentiation 183
4. Summary 189
References 190
Chapter 6: Development of Germ Cells in the Mouse 198
1. Origin of the Germ Cell Lineage 198
2. Specification of Primordial Germ Cells in Mice 199
3. Migration and Population of the Urogenital Ridge 203
4. Maintaining Pluripotency in the Germ Cell Lineage 205
5. Sex-Specific Development of Germ Cells in XX and XY Gonads 206
6. The Sexually Dimorphic Cell Cycle 208
7. Epigenetic Regulation in the Mouse Germ Line 211
8. Sexually Dimorphic Epigenetic Regulation 213
9. Germ Cells to Stem Cells and Back 215
10. Conclusions 218
Acknowledgments 219
References 219
Chapter 7: The Neuroendocrine Control of Sex-Specific Behavior in Vertebrates: Lessons from Mammals and Birds 226
1. Introduction: General Principles and the Scope of the Chapter 227
2. Historical Overview 229
3. Reproductive Behavior in Mammals 235
4. Reproductive Behaviors in Birds 244
5. Unanswered Questions and Future Directions 254
References 255
Index 262
Contents of Previous Volumes 268
Color Plate Section 295

Produkt-Details

• Erscheint lt. Verlag: 19.1.2009
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie
• Themenwelt: Naturwissenschaften ► Biologie ► Evolution
• Themenwelt: Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
• Themenwelt: Naturwissenschaften ► Biologie ► Zoologie
• Themenwelt: Technik
• ISBN-10: 0-08-092284-8 / 0080922848
• ISBN-13: 978-0-08-092284-3 / 9780080922843