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Genomics, Proteomics and Metabolomics in Nutraceuticals and Functional Foods

Online Resource
352 Seiten
2010
Wiley-Blackwell (Hersteller)
978-0-8138-2147-4 (ISBN)
CHF 309,95 inkl. MwSt
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Genomics is defined as the study of an organism's genome and includes intensive efforts to determine the entire DNA sequence of an organism. Proteomics is defined as a large-scale study of proteins. It is the next step and more complex than genomics.
The nutraceutical and functional food field is rapidly growing in diverse sectors, including academic, commercial and government. This has brought a corresponding shift in research focus and in public awareness. Understanding the relevance of the scientific principles in determining the safety and effectiveness of functional foods and nutraceuticals is increasingly important. It is becoming increasingly evident that genomic research technologies will be used in the coming years and there is a need to provide resources that will facilitate this growth. This book incorporates the most recent advances in the three major sectors of the field within one volume. Genomics, proteomics, and metobolomics represent three major scientific research areas that contribute to nutraceutical and functional food research for studies of effectiveness and safety.

Debasis Bagchi, Ph.D., Adjunct Professor of Medicinal Chemistry, Pharmacological and Pharmaceutical Sciences Department, University of Houston, TX. Francis Lau, InterHealth USA, Benecia, CA. Manashi Bagchi, Ph.D., InterHealth USA, Benecia, CA.

Editors and Contributors ix

Preface xiii

Section 1 Introduction

1. Recent advances in nutraceuticals and functional foods 3
Francis C. Lau, Debasis Bagchi, Shirley Zafra-Stone, and Manashi Bagchi

2. Novel omics technologies in nutraceutical and functional food research 11
Xuewu Zhang, Wei Wang, and Kaijun Xiao

Section 2 Genomics

3. Nutrigenomics and statistical power: The ethics of genetically informed nutritional advice 23
Ruth Chadwick

4. NutrimiRomics: The promise of a new discipline in nutrigenomics 35
Chandan K. Sen

5. Genomics in weight loss nutraceuticals 45
Debasis Bagchi, Francis C. Lau, Hiroyoshi Moriyama, Manashi Bagchi, and Shirley Zafra-Stone

6. Application of genomics and bioinformatics analysis in exploratory study of functional food 61
Kohsuke Hayamizu and Aiko Manji

7. Genomics as a tool to characterize anti-inflammatory nutraceuticals 73
Sashwati Roy

8. Application of nutrigenomics in gastrointestinal health 83
Lynnette R. Ferguson, Philip I. Baker, and Donald R. Love

9. Genomics analysis to demonstrate the safety and efficacy of dietary antioxidants 95
Nilanjana Maulik

10. Genomics applied to nutrients and functional foods in Japan: State of the art 127
Yuji Nakai, Akihito Yasuoka, Hisanori Kato, and Keiko Abe

11. Genomic basis of anti-inflammatory properties of Boswellia extract 155
Golakoti Trimurtulu, Chandan K. Sen, Alluri V. Krishnaraju, and Krishanu Sengupta

12. Nutrigenomic Perspectives on Cancer Chemoprevention with anti-inflammatory and antioxidant Phytochemicals: NF-κB and Nrf2 Signaling Pathways as Potential Targets 175
Hye-Kyung Na and Young-Joon Surh

Section 3 Proteomics

13. Proteomics analysis of the functionality of Toona sinensis by 2D-gel electrophoresis 201
Sue-Joan Chang and Chun-Yung Huang

14. Application of proteomics in nutrition research 213
Baukje de Roos

15. Proteomics approach to assess the potency of dietary grape seed proanthocyanidins 225
Hai-qing Gao

16. Proteomics and its application for elucidating insulin deregulation in diabetes 241
Hyun-Jung Kim and Chan-Wha Kim

Section 4 Metabolomics

17. NMR-based-metabolomics strategy for the classification and quality control of nutraceuticals and functional foods 265
Yulan Wang and Huiru Tang

18. Metabolomics: An emerging post-genomic tool for nutrition 271
Phillip Whitfield and Jennifer Kirwan

19. Evaluation of the beneficial effects of phytonutrients by metabolomics 287
Katia Nones and Silas G. Villas-Bˆoas

Section 5 Nutrigenomics in Human Health

20. Omics for the development of novel phytomedicines 299
Kandan Aravindaram, Harry Wilson, and Ning-Sun Yang

21. Contribution of omics revolution to cancer prevention research 315
Nancy J. Emenaker and John A. Milner

Index 329

Erscheint lt. Verlag 26.3.2010
Verlagsort Hoboken
Sprache englisch
Themenwelt Medizin / Pharmazie Gesundheitsfachberufe Diätassistenz / Ernährungsberatung
Technik Lebensmitteltechnologie
ISBN-10 0-8138-2147-9 / 0813821479
ISBN-13 978-0-8138-2147-4 / 9780813821474
Zustand Neuware
Informationen gemäß Produktsicherheitsverordnung (GPSR)
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