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Antioxidants Effects in Health

The Bright and the Dark Side

Seyed Mohammad Nabavi, Ana Teresa Sanches Silva (Herausgeber)

Buch | Softcover

912 Seiten

2022
Elsevier Science Publishing Co Inc (Verlag)
9780128190968 (ISBN)

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Antioxidants Effects in Health: The Bright and the Dark Side examines the role that antioxidants play in a variety of health and disease situations. The book discusses antioxidants’ historical evolution, their oxidative stress, and contains a detailed approach of 1) endogenous antioxidants, including endogenous sources, mechanisms of action, beneficial and detrimental effects on health, in vitro evidence, animal studies and clinical studies; 2) synthetic antioxidants, including sources, chemistry, bioavailability, legal status, mechanisms of action, beneficial and detrimental effects on health, in vitro evidence, animal studies and clinical studies; and 3) natural antioxidants, including sources, chemistry, bioavailability, mechanisms of action, possible prooxidant activity; beneficial and detrimental effects on health, in vitro evidence, animal studies and clinical studies. Throughout the boo, the relationship of antioxidants with different beneficial and detrimental effects are examined, and the current controversies and future perspectives are addressed and explored. Antioxidants Effects in Health: The Bright and the Dark Side evaluates the current scientific evidence on antioxidant topics, focusing on endogenous antioxidants, naturally occurring antioxidants and synthetic antioxidants. It will be a helpful resource for pharmaceutical scientists, health professionals, those studying natural chemistry, phytochemistry, pharmacognosy, natural product synthesis, and experts in formulation of herbal and natural pharmaceuticals.

Seyed Mohammad Nabavi is biotechnologist and Senior Scientist of Applied Biotechnology Research Center, Baqiyatallah University of Medical Science and member of Iran’s national elites foundation. His research focused on the health-promotion effects of natural products. He is author/co-author of 200 publications in international journal, 51 communications at national and international congress and eight chapters in book series. He is referee of several international journals. Ana Sanches Silva is a researcher at the National Institute of Agrarian and Veterinary Research (INIAV, IP). She obtained a degree in Pharmacy from the University of Coimbra, Portugal, and received her European Ph.D. in Pharmacy from the University of Santiago de Compostela, Spain, with honors. In addition, she was awarded with the prize for best doctorate student. Ana Sanches-Silva has a remarkable track record (over 100 scientific contributions in peer-reviewed journals or book chapters). She has more than 300 communications in national and international conferences. Her research interests are focused on the evaluation of safety and composition of food and food packaging. Moreover, her special interest is the study of food bioactive compounds and dietary supplements, and development of analytical methodologies for the analysis of bioactive compounds in food.

Part 1. Introduction
1. Evolution of antioxidants over times
2. The oxidative stress: Causes, free radicals, targets, mechanisms, affected organs, effects, indicators
3. Food autooxidation

Part 2. Endogenous antioxidants
4. Alpha lipoic acid
5. Bilirubin
6. Catalase
7. Coenzyme Q
8. Ferritin
9. Glucose-6-phosphate-dehydrogenase
10. Glutathione peroxidise
11. Glutathione reductase
12. Gluthathione
13. Superoxide dismutase
14. Uric acid

Part 3. Synthetic antioxidants: bright and the dark side
15. Ascorbyl palmitate
16. Butylated hydroxyanisole (BHA)
17. Butylated hydroxytoluene (BHT)
18. Erythorbic acid (D-ascorbic acid)
19. Nordihydroguaiaretic acid (NDGA)
20. Octyl gallate (OG)
21. Propyl gallate (PG)
22. tert-butylhydroxyquinone (TBHQ)

Part 4. Natural occurring antioxidants: bright and the dark side
23. Amino acids
24. Carnosine
25. Carnosol
26. Carotenoids (xanthophylls and carotenes)
27. Citric acid
28. Coenzyme Q
29. Curcumin
30. Flavonoids
31. Lecithin
32. Lignans
33. Organosulfur compounds( allyl sulphide, indoles)
34. Phenolic acids
35. Phytic acid
36. Protein hydrolysates
37. Saponins
38. Selenium
39. Sterols
40. Stilbenes
41. Tartaric acid
42. Turmeric
43. Uric acid
44. Vanillin
45. Vitamin A (retinol)
46. Vitamin C
47. Vitamin E (tocopherols and tocotrienols)
48. Vitamin K
49. Zinc

Part 5. Antioxidants and diseases: Beneficial and detrimental effects
50. Antioxidants and cancer
51. Antioxidants and cardiovascular diseases
52. Antioxidants and cataracts/ age-related macular degeneration
53. Antioxidants and cognitive decline in elderly
54. Antioxidants and dentistry
55. Antioxidants and diabetes
56. Antioxidants and gastric lesions
57. Antioxidants and immune functions
58. Antioxidants and infertility
59. Antioxidants and liver diseases
60. Antioxidants and neurological disorders and psychiatric disorders
61. Antioxidants and respiratory diseases
62. Antioxidants and viral diseases

Part 6: Actual and future perspectives on antioxidants
63. Duality: antioxidants/prooxidants
64. Food and food supplements antioxidants: Targets in human antioxidant system and effects on the production of endogenous antioxidants
65. Concluding remarks and future perspectives

Erscheinungsdatum	27.06.2022
Zusatzinfo	50 illustrations (10 in full color); Illustrations
Sprache	englisch
Maße	191 x 235 mm
Gewicht	1880 g
Themenwelt	Sachbuch/Ratgeber ► Gesundheit / Leben / Psychologie ► Alternative Heilverfahren
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
	Medizin / Pharmazie ► Naturheilkunde ► Phytotherapie
	Medizin / Pharmazie ► Pharmazie
	Studium ► Querschnittsbereiche ► Epidemiologie / Med. Biometrie
	Technik
ISBN-13	9780128190968 / 9780128190968
Zustand	Neuware