Ciba Foundation Symposium 197 – Variation in the Human Genome

Ciba Foundation (Autor)

Software / Digital Media

340 Seiten

2007
Wiley-Blackwell (Hersteller)
978-0-470-51488-7 (ISBN)

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The mapping of human genes is proceeding rapidly. Genes associated with specific inherited diseases are being identified, often providing insight into the molecular cause of the disease. At the moment, however, little consideration is being given to the variation present in different human populations. Variation in the Human Genome discusses methods of analysing population genetic data and how contemporary genetic heterogeneity arises during the evolution and migration of human populations. Specific disorders such as cystic fibrosis, beta-thalassaemia, fragile X, phenylketonuria and tumour development susceptibility are used to illustrate this genetic variability and mechanisms of gene mutation and evolution.

Derek J. Chadwick and Gail Cardew are editors for Variation in the Human Genome and other scientific titles.

Partial table of contents: Phyogeographic Variability in Traditional Societies (R. Ward & D. Valencia). Interpreting Genetic Variability: The Effects of Shared Evolutionary History (P. Donnelly). Microsatellites: Evolution and Mutational Processes (N. Freimer & M. Slatkin). Genetic and Geographical Variability on Cystic Fibrosis: Evolutionary Considerations (J. Bertranpetit & F. Calafell). Population Genetics of Tumours (W. Bodmer & I. Tomlinson). World Distribution of HLA Alleles and Implications for Disease (J. Bodmer). The Genetics of Common Diseses: The Implications of Population Variability (D. Weatherall). Final Discussion. Summary. Indexes.

Erscheint lt. Verlag	28.9.2007
Verlagsort	Hoboken
Sprache	englisch
Maße	155 x 235 mm
Gewicht	650 g
Themenwelt	Naturwissenschaften ► Biologie
ISBN-10	0-470-51488-4 / 0470514884
ISBN-13	978-0-470-51488-7 / 9780470514887
Zustand	Neuware