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Neuroendocrine-Immune Axis

Towards Understanding the Pathogenesis of Neurodegenerative Disorders

Rahul Shukla, Saba Naqvi, Monika S Deore, Ravinder Kaundal (Herausgeber)

Buch | Hardcover

415 Seiten

2026
Springer Verlag, Singapore
978-981-95-5087-6 (ISBN)

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This book discusses the mutual interactions between neurons and other types of cells during neurological and immunological processes within the Central Nervous System (CNS) for understanding the pathophysiology of various neurological diseases and advancing the diagnosis, prevention, and intervention. It also addresses the immune function of both glial cells and neurons, and the roles they play in regulating inflammatory processes and maintaining homeostasis of the CNS. This book also examines the role of the neuro-immune axis and its targetability in relation to major depression and autism spectrum disorder and reviews the role of nanotechnology in modulating the neuroimmune axis. Further, the book discusses the specific arms of the peripheral immune system and other types of immune responses in modulating neurodegenerative disorders. It also reviews the role of cytokines in neurodegeneration, mechanisms of expression and action, and clinical relevance. Lastly, the book reviews thedrug repurposing strategy to search for new therapeutic options against neurodegenerative diseases. This book as such is invaluable for students, researchers, and scientists of neurosciences, pharmaceutic sciences, and immunology.

Dr. Rahul Shukla is working as an Assistant Professor at Department of Pharmaceutics, NIPER Raebareli, India, an Institute of National Importance, under the Ministry of Chemicals & Fertilizers, Government of India. Dr. Saba Naqvi is working as an Assistant Professor in the Department of Pharmacology & Toxicology/Regulatory Toxicology. She obtained her master’s from Jamia Hamdard, New Delhi, and her Ph.D. in 2013 from Jamia Hamdard in collaboration with AIIMS, New Delhi. Dr. Monika S Deore is Ph.D. in pharmacology and toxicology from NIPER Raebareli, India. She did her M.S. (Pharm) in regulatory toxicology from NIPER Mohali, India, B. Pharm from L.N.J.D.P College of Pharmacy, Manur. Dr. Ravinder Kaundal is working as Assistant Professor at NIPER Raebareli. He has done his MS (Pharm.) and Ph.D. in Pharmacology and Toxicology from NIPER-SAS Nagar, India.

Chapter 1. Neuroimmune crosstalk in neurodegeneration.- Chapter 2. Harnessing nanotechnology in Modulating neuroimmune axis.- Chapter 3. Role of peripheral immune alterations in neurodegeneration.- Chapter 4. Integration of peripheral and central immune alteration in neurodegeneration.- Chapter 5. Cytokine alteration and targeting in neurodegeneration: Role of nanomaterials.- Chapter 6. Natural product assembly in nano formulation: Importance in neurodegenerative diseases.- Chapter 7. Nanoprebiotics and Nanoprobiotics in Gut health: Link with neuroprotection.- Chapter 8. Nano corona, immunity switch, and Hide and Seek interactions of nanomaterials in neuroimmune crosstalk.- Chapter 9. Neuroimmune signalling: Novel Emerging Options to Treat neurodegeneration.- Chapter 10. Nanotheranostics targeting neuroimmune signalling: The mind knockout.- Chapter 11. Mitochondrial health and critical neurotransmitters in neurodegeneration.- Chapter 12. Evolving pharmacotherapies involving neuroimmune crosstalk.- Chapter 13. Drug repurposing and repositioning in neurodegeneration.- Chapter 14. Recent therapies including Gene therapy, immunotherapy in overcoming the gaps in treatment of neurodegeneration.

Erscheint lt. Verlag	13.2.2026
Zusatzinfo	43 Illustrations, color; 54 Illustrations, black and white
Verlagsort	Singapore
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Studium ► 1. Studienabschnitt (Vorklinik) ► Anatomie / Neuroanatomie
	Studium ► Querschnittsbereiche ► Infektiologie / Immunologie
	Naturwissenschaften ► Biologie ► Humanbiologie
	Naturwissenschaften ► Biologie ► Zoologie
Schlagworte	Gut Microbiome dysregulation • Hypothalamus-pituitary-adrenal hormone dynamics • neurodegenerative diseases • Neuroimmune axis • Neuroimmune crosstalk
ISBN-10	981-95-5087-4 / 9819550874
ISBN-13	978-981-95-5087-6 / 9789819550876
Zustand	Neuware