Bioinformatics of Autoimmune Diseases
CRC Press (Verlag)
978-1-041-16611-5 (ISBN)
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Structured to bridge foundational immunology with advanced computational analysis, this book offers readers a progression from the molecular mechanisms of immune function and dysfunction to the bioinformatics pipelines used to investigate them. Early chapters provide a thorough grounding in immune cell biology, immune checkpoints, and disease pathogenesis. Subsequent chapters guide readers through practical analyses of autoimmune disease data, covering RNA-Seq, variant analysis, microbiome profiling, ATAC-Seq, ChIP-Seq, single-cell sequencing, and gene therapy and autoimmune diseases. Bioinformatics tools are introduced using Python with step-by-step workflows, enabling hands-on engagement with real datasets.
Written by a professor of bioinformatics and developer of bioinformatics tools, the book draws from over a decade of broad experience in computational biology. With detailed illustrations, curated datasets, and a clear emphasis on reproducibility, it serves as a foundational resource for graduate students, clinicians, biomedical researchers, and anyone seeking to decode the bioinformatics foundations and mechanisms driving autoimmune disease.
Hamid D. Ismail is a bioinformatics scholar and research high-performance computing center administrator. His research bridges biology and computation, focusing on bioinformatics tools, disease genomics, and machine learning. He is the author of several acclaimed textbooks that advance education and research in computational biology and genomics.
Chapter 1 Immune Mechanisms and Major Autoimmune Diseases Chapter 2 Genetic Markers in Autoimmunity Chapter 3 Bioinformatics Design for Autoimmune Research Chapter 4 Bioinformatics Databases Chapter 5 RNA Sequencing Chapter 6 Variant Analysis Chapter 7 DNA-Protein Interactions and Autoimmune Diseases Chapter 8 ATAC-Seq for Autoimmune Diseases Chapter 9 Roles of Bacteria in Autoimmune Diseases Chapter 10 Gene Therapy and Autoimmune Diseases
| Erscheint lt. Verlag | 28.2.2026 |
|---|---|
| Reihe/Serie | Chapman & Hall/CRC Computational Biology Series |
| Zusatzinfo | 43 Tables, black and white; 34 Line drawings, color; 40 Line drawings, black and white; 34 Illustrations, color; 40 Illustrations, black and white |
| Verlagsort | London |
| Sprache | englisch |
| Maße | 178 x 254 mm |
| Themenwelt | Studium ► Querschnittsbereiche ► Infektiologie / Immunologie |
| Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie | |
| ISBN-10 | 1-041-16611-7 / 1041166117 |
| ISBN-13 | 978-1-041-16611-5 / 9781041166115 |
| Zustand | Neuware |
| Informationen gemäß Produktsicherheitsverordnung (GPSR) | |
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