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Bioinformatics

A Practical Guide to the Analysis of Genes and Proteins

Andreas D. Baxevanis, B. F. Francis Ouellette (Herausgeber)

Online Resource

384 Seiten

2006
Wiley-Interscience (Hersteller)
9780470110607 (ISBN)

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A reference for the biologist who uses the internet for the analysis of DNA and protein sequence data.

"A reference that should be in the personal library of any biologist who uses the Internet for the analysis of DNA and protein sequence data" --Science

Dr. Baxevanis is Associate Director for Intramural Research, and Director for Computational Genomics at the National Human Genome Research Institute, National Institutes of Health. He received his BS in biological sciences from Cornell University in 1984 and his PhD in the Department of Biology at The Johns Hopkins University in 1991. His research focuses on protein structure-function relationships, positional cloning, and the development of new methods for analysis of gene expression data. His accom-plishments have been recognized by the Bodossaki Foundation in Greece, who awarded him their 1999 Academic Prize in Medicine and Biology. B.F. Francis Ouellette is Director of the Bioinformatics Core facility at the Center for Molecular Medicine and Therapeutics, University of British Columbia, and Director of the Bioinformatics Core facility for the Canadian Genetic Diseases Network. He held the position of GenBank coordinator for the National Center for Biotechnology Information at the National Institutes of Health. He received his PhD from the Department of Biology at McGill University in 1991, and is the founder and moderator of bionet.molbio.yeast, a Usenet discussion forum for the yeast genomics community.

The Internet and the Biologist (A. Baxevanis). The GenBank Sequence Database (B. Ouellette).

Structure Databases (C. Hogue & S. Bryant).

Sequence Analysis Using GCG (B. Butler).

Information Retrieval from Biological Databases (A. Baxevanis).

The NCBI Data Model (J. Ostell & J. Kans).

Sequence Alignment and Database Searching (G. Schuler).

Practical Aspects of Multiple Sequence Alignment (A. Baxevanis).

Phylogenetic Analysis (M. Hershkovitz & D. Leipe).

Predictive Methods Using Nucleotide Sequences (J. Fickett).

Predictive Methods Using Protein Sequences (A. Baxevanis & D. Landsman).

Of Mice and Men: Navigating Public Physical Mapping Databases (L. Stein) .

ACEDB: A Database for Genome Information (S. Walsh, et al.).

Submitting DNA Sequence to the Databases (J. Kans & B. Ouellette) .

Appendices.

Index.