Quantitative Gas Chromatography-Mass Spectrometry in the Life Sciences

Principles and Bioanalytical Applications

Dimitrios Tsikas (Autor)

Buch | Softcover

734 Seiten

2025
Elsevier - Health Sciences Division (Verlag)
9780443300967 (ISBN)

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Quantitative Gas Chromatography-Mass Spectrometry: Principles in Life Sciences and Biochemical Applications provides an in-depth exploration of the principles and practices of GC-MS. This comprehensive guide caters to researchers, academics, and graduate students engaged in analytical chemistry, offering both theoretical knowledge and practical applications. The book is structured to introduce the fundamentals before delving into advanced techniques, ensuring a thorough understanding for all readers. The book covers essential topics such as gas chromatography-tandem mass spectrometry, liquid chromatography-tandem mass spectrometry, and the use of stable isotopes and labeled analogs. It also presents practical advice on method development, validation, and quality control.

Additionally, it addresses common issues and troubleshooting in GC-MS, making it a valuable resource for those in fields like Biochemistry, Pharmacology, Forensic Medicine, and Metabolomics.

Dimitros Tsikas is a Professor at the Institute of Toxicology, Core Unit Proteomics in Hannover Medical School.

Preface
Acknowledgements
1. Principles of quantitative analysis by GC-MS, GC-MS/MS and GC-HRMS
2. Extraction and analytical derivatization techniques in GC-MS
3. Quantitative GC-MS analysis of amino acids
4. GC-MS analysis of post-translational modifications
5. Quantitative GC-MS analysis of biogenic amines and polyamines
6. Quantitative GC-MS analysis of drugs
7. Biomedical applications of GC-MS and GC-MS/MS in human studies
8.Perspectives of GC-MS in the life sciences
List of abbreviations used
List of Enzyme Commission (EC) numbers
Subject and Name Index

Erscheinungsdatum	13.12.2025
Verlagsort	Philadelphia
Sprache	englisch
Maße	152 x 229 mm
Gewicht	450 g
Themenwelt	Naturwissenschaften ► Biologie
Themenwelt	Naturwissenschaften ► Chemie ► Analytische Chemie
ISBN-13	9780443300967 / 9780443300967
Zustand	Neuware