Antibacterial activity of Celecoxib

Farida Allal, Khouloud KOURIMI, NIHAL KHATOUI (Autoren)

Buch | Softcover

60 Seiten

2025
Our Knowledge Publishing (Verlag)
978-620-8-57812-1 (ISBN)

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Strategies for repositioning and forming eutectic mixtures by binary combination of Active Principle/Coformer or Active Principle/Active Principle are widely used to combat multi-resistant bacteria and increase solubility, bioavailability and consequently therapeutic effect. The choice of coformer is based on its chemical structure and the presence of proton-donating and proton-accepting functional groups capable of establishing non-covalent intermolecular interactions, such as hydrogen bonding, Van Der Waals forces and pi-pi interactions. The active ingredient chosen for repositioning is Celecoxib. The coformers are salicylic acid (A.SAL), maleic acid (A.MAL), nicotinamide (NIC), succinic acid (A.SUC) and cinnamic acid (A.CIN).

Dr. ALLAL Farida, research professor at Amar Telidli University, Laghouat, Algeria. My field of interest is thermodynamics and its applications to binary and multi-component mixtures, as well as the evaluation of intermolecular interactions in binary combinations of active ingredients.

Erscheinungsdatum	31.01.2025
Sprache	englisch
Maße	152 x 229 mm
Gewicht	95 g
Themenwelt	Naturwissenschaften ► Chemie ► Physikalische Chemie
Schlagworte	Antibacterial Activity • BMC • Celecoxib • Coformers • COX-2 Inhibitor • MIC • Solubility.
ISBN-10	620-8-57812-4 / 6208578124
ISBN-13	978-620-8-57812-1 / 9786208578121
Zustand	Neuware