Proteomics for Biological Discovery
Wiley-Liss Inc.,U.S. (Hersteller)
978-0-470-00774-7 (ISBN)
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Written by recognized experts in the study of proteins,Proteomics for Biological Discovery begins bydiscussing the emergence of proteomics from genome sequencingprojects and a summary of potential answers to be gained fromproteome-level research. The tools of proteomics, from conventionalto novel techniques, are then dealt with in terms of underlyingconcepts, limitations and future directions. An invaluable sourceof information, this title also provides a thorough overview of thecurrent developments in post-translational modification studies,structural proteomics, biochemical proteomics, microfabrication,applied proteomics, and bioinformatics relevant to proteomics.
* Presents a comprehensive and coherent review of the majorissues faced in terms of technology development, bioinformatics,strategic approaches, and applications
* Chapters offer a rigorous overview with summary of limitations,emerging approaches, questions, and realistic future industry andbasic science applications
* Discusses higher level integrative aspects, including technicalchallenges and applications for drug discovery
* Accessible to the novice while providing experiencedinvestigators essential information
Proteomics for Biological Discovery is anessential resource for students, postdoctoral fellows, andresearchers across all fields of biomedical research, includingbiochemistry, protein chemistry, molecular genetics,cell/developmental biology, and bioinformatics.
TIMOTHY D. VEENSTRA, PhD, is the Director of the Laboratoryof Proteomics and Analytical Technologies, National CancerInstitute-Frederick, Frederick, Maryland. JOHN R. YATES III, PhD, is in the Department of CellBiology, The Scripps Research Institute, La Jolla, California.
Forward.
Genomics: Where We Are and Where Are We Going (T. Pawson).
PART I: FOUNDATIONS OF PROTEOMICS.
1. Mass Spectrometry: The Foundations of Proteomics (T.Veenstra).
2. Proteomic Analysis by Two-Dimensional Polycrylamide GelElectrophoresis (J. Celis).
3. Isotope Labeling in Quantitative Proteomics (C.Fenselau).
4. Proteome Analysis of Post-Translational Modifications (T.Veenstra).
5. Technologies for Large Scale Proteomic Tandem MassSpectrometry (J. Yates).
6. Protein Fractionation Methods for Proteomics (T.Rabilloud).
PART II: FUNCTIONAL PROTEOMICS.
7. Protein Localization by Cell Imaging (T. Davis).
8. Characterization of Functional Protein Complexes (C.Robinson).
9. Structural Proteomics by NMR (M. Clore).
PART III: NOVEL APPROACHES IN PROTEOMICS.
10. Protein Microarrays (D. Munroe).
11. Microfluidics (C. Lee).
12. Single Cell Proteomics (N. Dovichi).
13. Diagnostic Proteomics (H. Issaq).
14. Automation in Proteomics (T. Veenstra).
15. Bioinformatics (D. Liebler).
Index.
| Verlagsort | New York |
|---|---|
| Sprache | englisch |
| Themenwelt | Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie |
| Naturwissenschaften ► Chemie | |
| ISBN-10 | 0-470-00774-5 / 0470007745 |
| ISBN-13 | 978-0-470-00774-7 / 9780470007747 |
| Zustand | Neuware |
| Informationen gemäß Produktsicherheitsverordnung (GPSR) | |
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