Adrenoceptors
Springer International Publishing (Verlag)
978-3-031-66775-6 (ISBN)
- Adrenoceptors have been prototypes for rationale drug design and receptor structure and function
- Adrenoceptors are target of guideline-recommended drugs for >30 diseases from heart to prostate
- Most recent and most comprehensive collection of chapters and experts on state-of-the-art research on adrenoceptors
Adrenoceptors have been at the forefront of physiological and pharmacological research for a century. They served as prototypes for rationale drug design as recognized by a Nobel Prize to Sir James Black and for the molecular understanding and structure of G protein-coupled receptors as recognized by a Nobel Prize to Brian Kobilka and Robert J. Lefkowitz.
Drugs directly or indirectly targeting adrenoceptors have become guideline-recommended treatments for more than 30 human and various animal diseases.
This volume assembles leading experts on various types of adrenoceptor research to provide concise insight into the current standing and future direction of uses of adrenoceptor-targeted drugs and research in this field.
Introduction: a short history of adrenoceptor research
Structures of Adrenoceptors
Genetic Variants of Adrenoceptors
Adrenoceptors: Receptors, Ligands and Their Clinical Uses, Molecular Pharmacology and Assays
Signalling of adrenoceptors: canonical pathways and new paradigms
Presynaptic Adrenoceptors
Roles of b-adrenoceptor subtypes and therapeutics in human cardiovascular disease:- heart failure, tachyarrhythmias and other cardiovascular disorders
Adrenoceptors and Hypertension
Adrenoceptors in the Lower Urinary Tract
Asthma and COPD: A Focus on b-Agonists - Past, Present and Future
Adrenoceptors in the Eye- Physiological and Pathophysiological Relevance
Adrenoceptors: A Focus on Psychiatric Disorders and Their Treatments
Locus Coeruleus and Noradrenergic Pharmacology in Neurodegenerative Disease
Clinical use of adrenergic receptor ligands in acute care settings
Adrenoceptor expression and function in the endocrine pancreas
b-adrenoceptors in cancer: old players and new perspectives.
| Erscheinungsdatum | 05.09.2024 |
|---|---|
| Reihe/Serie | Handbook of Experimental Pharmacology |
| Zusatzinfo | 70 b/w illustrations |
| Verlagsort | Cham |
| Sprache | englisch |
| Maße | 155 x 235 mm |
| Einbandart | gebunden |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie |
| Medizin / Pharmazie ► Pharmazie | |
| Naturwissenschaften ► Chemie ► Physikalische Chemie | |
| Schlagworte | adrenoceptors • Cardiovascular System • central nervous system • Metabolism • Respiratory System |
| ISBN-10 | 3-031-66775-1 / 3031667751 |
| ISBN-13 | 978-3-031-66775-6 / 9783031667756 |
| Zustand | Neuware |
| Informationen gemäß Produktsicherheitsverordnung (GPSR) | |
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