Membrane fusion induced by Vesicular Stomatitis Virus

Fabiana Carneiro (Autor)

Buch | Softcover

64 Seiten

2024
Our Knowledge Publishing (Verlag)
9786207334414 (ISBN)

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The work presented here by Dr. Fabiana Carneiro aimed to elucidate the mechanism of entry of enveloped viruses, using the vesicular stomatitis virus as a model. The entry of enveloped viruses into their host cells always involves a membrane fusion step, either with the cell plasma membrane or with that of the endocytic vesicle. In this context, the work aims to understand the structure of the surface glycoprotein present on the envelope, as well as the amino acids involved in the fusion process. To this end, different types of lipids were used in experiments involving biophysical techniques such as fluorescence, circular dichroism and calorimetry. Molecular dynamics analyses were carried out to study interactions on nanometric scales and mass spectrometry identified the sequence responsible for this fusion between membranes. A complete thesis, described in 6 published scientific articles.

Degree in Biological Sciences - UFRJ (1999), Master's in Biological Chemistry - UFRJ (2000), PhD in Biological Chemistry - UFRJ and Université Libre de Bruxelles (2004). Post-doc in Virology - New York University (2006), Biophysics - University of Lisbon (2008) and Molecular Dynamics - UFRJ (2009). Currently Adjunct Professor at UFRJ.

Erscheinungsdatum	04.04.2024
Sprache	englisch
Maße	152 x 229 mm
Gewicht	108 g
Themenwelt	Naturwissenschaften ► Biologie ► Allgemeines / Lexika
Themenwelt	Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie
Schlagworte	membrane fusion • pH • Virology • VSV
ISBN-13	9786207334414 / 9786207334414
Zustand	Neuware