Lipid Analysis in Biology, Health, and Disease

Sanjoy K. Bhattacharya (Herausgeber)

Buch | Softcover

472 Seiten

2025
Academic Press Inc (Verlag)
978-0-443-19116-9 (ISBN)

Infos

Lipid Analysis in Biology, Health, and Disease bridges the gap between discovery science and clinical lipidology, empowering both scientific and medical communities to apply lipid analysis and understanding in new research, as well as diagnosis and management of diseases. Here, international experts in the field begin with the basic biology of the lipids, followed by methods and technology for study, and lipids in lab medicine and epidemiology. This book uniquely combines biology and analysis to drive healthcare advances, with a diverse range of technologies and analytic methods considered. Basic lipid biology chapters discuss membrane expansion, lysosomal positioning, mitochondrial biogenesis, lipid-protein interactions, molecular dynamics, cholesterol transport, immune activation and inflammation, lipid droplets, and gender differences in lipid metabolism. Each disease chapter incorporates basic lipid epidemiology, risk factors, and genetic associations.

Autor

Sanjoy K. Bhattacharya, Ph.D. is a Tenured Professor of Ophthalmology and Research Scientist at the University of Miami Bascom Palmer Eye Institute. He is the founding Director of the Miami Integrative Metabolomics Research Center, the Director of the Ophthalmology Mass Spectrometry Core Facility/Shared Instrument Facility, and the Director of the Graduate Program in Vision Science and Investigative Ophthalmology at Miller School of Medicine. His research adopts a multidisciplinary approach which includes mass spectrometric proteomic and lipidomic approaches to study neurodegenerative diseases, and majorly focus is a group of progressive irreversible blinding diseases collectively called glaucoma and also a group of demyelinating diseases termed multiple sclerosis that frequently is associated with visual impairment preceding neurological deficits.

Inhalt

Section 1: Basic Biology of Lipids 1. Membrane Expansion 2. Lysosomal Positioning and Movement 3. Mitochondrial Biogenesis and Lipids 4. Mitochondrial Biogenesis 5. Lipid-Protein Interactions and Molecular Dynamics Simulation 6. Cholesterol Transport 7. Immune Activation and Inflammation 8. Lipid Droplets in Biology 9. Gender Differences in Lipid Metabolism 10. Circadian Rhythmicity 11. Cancer: Lipid Metabolism in Pancreatic Cancer 12. Neuroscience by a Group of Authors Section 2: Analytical Technology 13. Lipid Imaging: Microscopy-Based Techniques for Lipid Membrane Characterization 14. GC-MS Candice Ulmer 15. LC-MS/MS 16. NMR Section 3: Lipids in Lab Medicine 17. Methods in Lab Medicine Part I 18. Methods in Lab Medicine Part II Section 4: Lipids in Clinical Medicine 19. Engineering of Lipid Delivery Systems 20. Drug Delivery Systems for Lipids 21. Clinical Medicine Related to CNS Disorders 22. Inflammatory Bowel Disease 23. Atherosclerosis and Inflammation 24. Measurement of Lipids, New Paradigms, And Ideas Section 5: Epidemiology 25. Identifying Associations of Lipids With Diseases in Large Prospective Cohort Studies and Randomized Trials 26. Risk Prediction

Produkt-Details

• Erscheint lt. Verlag: 1.6.2025
• Verlagsort: San Diego
• Sprache: englisch
• Maße: 191 x 235 mm
• Themenwelt: Naturwissenschaften ► Biologie ► Biochemie
• Themenwelt: Naturwissenschaften ► Physik / Astronomie ► Angewandte Physik
• ISBN-10: 0-443-19116-6 / 0443191166
• ISBN-13: 978-0-443-19116-9 / 9780443191169
• Zustand: Neuware