Xas

Powerful spectroscopy to study cobalamins

Abdelhafid Mimouni (Autor)

Buch | Softcover

68 Seiten

2023
Our Knowledge Publishing (Verlag)
9786206648833 (ISBN)

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My book presents the applications of X-ray absorption spectroscopy (XAS) to the study of cobalamines, a family of organometallic molecules that play an essential role in the metabolism of all living things. I carried out several experiments on synthetic or biological samples, using different variants of XAS, such as XANES or EXAFS. I also used theoretical and numerical tools to interpret my data and compare them with those in the literature.In my book, I invite you to discover :- The base-off/base-on reaction of cobalamines, which modifies the geometry and stability of cobalamines.- The interaction between haptocorrin and cobalamins, which involves a modification of cobalt coordination and protection against oxidation.- The photolysis reaction of alkylcobalamines, leading to the disruption of the cobalt-carbon bond and the formation of a free radical.- Synthesis and characterization of cobaloximes, "model compounds of vitamin B12".- The interaction between glutathione and cobalamins, leading to the formation of glutathione-cobalamin complexes.

Dr. Abdelhafid Mimouni: Doctor in chemistry of bioinorganic systems, independent researcher.Professional experience: 1997 - 2017: Independent researcher in chemistry of bioinorganic systems. - Synthesized and characterized various organometallic and macromolecular compounds by different spectroscopic techniques.

Erscheinungsdatum	11.11.2023
Sprache	englisch
Maße	152 x 229 mm
Gewicht	114 g
Themenwelt	Naturwissenschaften ► Chemie ► Anorganische Chemie
Schlagworte	B12 • cobalamin • EXAFS • glutathione • photolysis • syntheses • XANES • XAS
ISBN-13	9786206648833 / 9786206648833
Zustand	Neuware