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Statistics with R for Microbiome Analysis - Mohsen Nady

Statistics with R for Microbiome Analysis

From Raw Reads to Relative Abundance

(Autor)

Buch | Hardcover
473 Seiten
2024
Delve Publishing (Verlag)
978-1-77469-902-7 (ISBN)
CHF 249,95 inkl. MwSt
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Covers the necessary analysis steps for dealing with microbiome data. The microbial samples are sequenced into raw reads or fastq files. These raw reads should be quality checked to assure their quality per base or per read. Then, after removing the errors, we can infer their exact amplicon sequence variants.
This book covers the necessary analysis steps for dealing with microbiome data. The microbial samples are sequenced into raw reads or fastq files. These raw reads should be quality checked to assure their quality per base or per read. Then, after removing the errors, we can infer their exact amplicon sequence variants (ASVs). After that, we taxonomically classify these sequences to represent the different taxonomy levels of species, genus, family, order, class, and phylum and generate a phylogenetic tree. Finally, the sequence data, the taxonomy table, phylogenetic tree, and sample data are combined in a single phyloseq object for ease of plotting, manipulation, and analysis of the different components of microbiome data. The final phyloseq object can also be cleaned for certain low prevalent sequences. All these steps are explained in R codes using a freely available microbiome data of 360 fecal samples.

Mohsen Nady is a pharmacist with a M.D. in Microbiology and a Diploma in Industrial Pharmacy. Besides, Mohsen has more than 10 years of experience in Statistics and Data Analytics. Mohsen has applied his skills to different projects related to Genomics, Microbiology, Biostatistics, Six Sigma, Data Analytics, Data Visualization, Building Apps, Geography, Market Analysis, Business Analysis, Machine Learning, etc. Mohsen also published his thesis in a high-impact journal that attracted many citations, where all the statistical analyses were performed by him in addition to the methodological part. Furthermore, Mohsen has earned different certificates, from top universities (Harvard, Johns Hopkins, Denmark, etc) in Statistics, Data Analytics, Data Visualization, and Machine Learning that highlight his outstanding diverse skills.

Chapter 1 Installing R and RStudio
Chapter 2 Getting started with R and RStudio
Chapter 3 Microbiome Data
Chapter 4 Quality Control of Reads
Chapter 5 Infer Sequence Variants
Chapter 6 Assign Taxonomy
Chapter 7 Phyloseq Object
Chapter 8 Phyloseq Abundance

Erscheinungsdatum
Sprache englisch
Maße 152 x 229 mm
Gewicht 272 g
Themenwelt Naturwissenschaften Biologie Mikrobiologie / Immunologie
Weitere Fachgebiete Land- / Forstwirtschaft / Fischerei
ISBN-10 1-77469-902-8 / 1774699028
ISBN-13 978-1-77469-902-7 / 9781774699027
Zustand Neuware
Informationen gemäß Produktsicherheitsverordnung (GPSR)
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