Methods in Kidney Cell Biology Part B
Academic Press Inc (Verlag)
978-0-12-820335-4 (ISBN)
Dr. Weimbs received his doctoral degree from the Department of Biochemistry of the University of Cologne, Germany, in 1993. He conducted postdoctoral research with Keith Mostov at the Department of Anatomy, University of California at San Francisco until 1999 where he investigated the role of SNARE proteins in membrane trafficking and epithelial cell polarity. In 1999, he joined the Department of Cell Biology in the Lerner Research Institute of the Cleveland Clinic as an Assistant Professor where he established his own research laboratory. Besides continuing his work on SNAREs and epithelial cell polarity his laboratory began to investigate molecular mechanisms underlying polycystic kidney disease (PKD). In 2005, Dr. Weimbs moved his lab to the University of California in Santa Barbara where he is currently a Professor in the Department of Molecular, Cellular, and Developmental Biology. Research on PKD in Dr. Weimbs’ laboratory has contributed to our understanding of the molecular pathogenesis and the function of polycystin-1, the protein affected in this disease. These contributions include the roles of mTOR and STAT signaling in PKD. Recent work has focused on developing new kidney-targeted therapeutics, the role of metabolic changes and tubular crystal deposition in PKD disease progression, and the use of dietary interventions for PKD therapy.
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2. Kidney harvesting and metabolite extraction for metabolomics studies in rodents
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3. Optical tissue clearing and immunolabeling in kidney research
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4. Urinary extracellular vesicles as a source of biomarkers reflecting renal cellular biology in human disease
Roman Müller
5. Intravital Visualization of the Primary Cilium, Tubule Flow, and Innate Immune Cells in the Kidney Utilizing an Abdominal Window Imaging Approach
Bradley Yoder
6. Novel fluorescence techniques to quantitate renal cell biology
Janos Peti-Peterdi
7. Manipulation of Renal Gene Expression Using Oligonucleotides
Vishal Patel
8. Methods for renal lineage tracing: in vivo and beyond
Thomas Carroll
9. In Vivo Magnetic Resonance Imaging Techniques for Structural and Functional Characterization of Murine Model Kidneys
Tim Kline
10. In vivo analysis of renal epithelial cells in zebrafish
Zhaoxia Sun
11. Visualizing gene expression during zebrafish pronephros development and regeneration
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12. Drosophila melanogaster and its nephrocytes – a versatile model for glomerular research
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| Erscheinungsdatum | 06.09.2019 |
|---|---|
| Reihe/Serie | Methods in Cell Biology |
| Verlagsort | San Diego |
| Sprache | englisch |
| Maße | 191 x 235 mm |
| Gewicht | 700 g |
| Themenwelt | Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie |
| Naturwissenschaften ► Biologie ► Zellbiologie | |
| ISBN-10 | 0-12-820335-8 / 0128203358 |
| ISBN-13 | 978-0-12-820335-4 / 9780128203354 |
| Zustand | Neuware |
| Informationen gemäß Produktsicherheitsverordnung (GPSR) | |
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