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Warlow's Stroke (eBook)

Practical Management
eBook Download: EPUB
2019 | 4. Auflage
John Wiley & Sons (Verlag)
978-1-118-49241-3 (ISBN)

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A practical textbook, based on a problem-oriented workflow, that will improve patients' likelihood of full recovery from stroke and prevent future strokes from occurring

Stroke is the leading cause of adult disability and is in the top five causes of death globally. Warlow's Stroke: Practical Management, 4th Edition takes a problem-oriented approach and addresses the questions posed by a stroke patient in the order they are likely to present in clinical practice, for instance, 'Is it a stroke?', 'What sort of stroke?', 'What caused it?', and 'What can be done about it?'.

Beginning with chapters phrased as questions, the book walks the reader through a standard clinical workflow, exploring the practical skills and assessment required at each stage of patient management. Early chapters cover: locating the vascular lesion, identifying the involved arterial territory, the role imaging should play, and the application thereof.

Subsequent chapters look at what causes a transient or persistent ischemic event, an intracerebral hemorrhage and a subarachnoid hemorrhage. Unusual causes of ischemic stroke and transient ischemic attack are also covered. The book then presents a practical approach to the management of stroke and transient ischemic attack; offers specific treatments for acute ischemic stroke and aneurysmal subarachnoid hemorrhage; provides ways for professionals to prevent first or recurrent stroke; and more.

Final chapters of the book discuss rehabilitation after stroke, how patients and carers can be supported in the short term and long term, prevention of recurrent stroke, and the organization of stroke services.

Warlow's Stroke: Practical Management, 4th Edition

  • Follows clinical workflow for stroke analysis
  • Features evidence-based approach throughout
  • Offers practical application aimed at improving patient outcomes
  • Written and edited by internationally renowned experts in the field

An essential resource for all practitioners involved in the care of patients who suffer from cerebrovascular disease, but particularly suitable for neurologists, residents, geriatricians, stroke physicians, radiologists and primary care physicians.



The Editors

Graeme J. Hankey MBBS, MD, FRACP, FRCPE, FAHA, FESO, FAAHMS, Professor of Neurology, Medical School, The University of Western Australia, Perth, Australia; and Consultant Neurologist, Sir Charles Gairdner Hospital, Perth, Western Australia

Malcolm Macleod BSc(Hons), MBChB, PhD, FRCP, Professor of Neurology and Translational Neurosciences at the University of Edinburgh, and Honorary Consultant Neurologist and Head of Neurology, NHS Forth Valley, UK

Philip B. Gorelick MD, MPH, FACP, FAHA, FAAN, FANA, Professor Translational Science and Molecular Medicine at Michigan State University, Grand Rapids, MI, USA; and Adjunct Professor, Davee Department of Neurology, Northwestern Feinberg School of Medicine, Chicago, IL, USA; and International Fellow, Population Health Research Institute affiliated with McMaster University Faculty of Health Sciences and Hamilton Health Sciences, Hamilton, ON, Canada; and Professor Emeritus, Department of Neurology and Rehabilitation, University of Illinois College of Medicine, Chicago, IL, USA

Christopher Chen BA, BMBCh, FRCP, Director, Memory Aging & Cognition Centre, National University Health System, Singapore; and Associate Professor, Department of Pharmacology, National University of Singapore, Singapore; and Senior Consultant Neurologist, Department of Psychological Medicine, National University Hospital, Singapore

Fan Z. Caprio MD, Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA

Heinrich Mattle MD, FRCPE, FAHA, FESO, Professor, Senior Consultant, Department of Neurology, University of Bern, Bern, Switzerland


A practical textbook, based on a problem-oriented workflow, that will improve patients' likelihood of full recovery from stroke and prevent future strokes from occurring Stroke is the leading cause of adult disability and is in the top five causes of death globally. Warlow's Stroke: Practical Management, 4th Edition takes a problem-oriented approach and addresses the questions posed by a stroke patient in the order they are likely to present in clinical practice, for instance, 'Is it a stroke?', 'What sort of stroke?', 'What caused it?', and 'What can be done about it?'. Beginning with chapters phrased as questions, the book walks the reader through a standard clinical workflow, exploring the practical skills and assessment required at each stage of patient management. Early chapters cover: locating the vascular lesion, identifying the involved arterial territory, the role imaging should play, and the application thereof. Subsequent chapters look at what causes a transient or persistent ischemic event, an intracerebral hemorrhage and a subarachnoid hemorrhage. Unusual causes of ischemic stroke and transient ischemic attack are also covered. The book then presents a practical approach to the management of stroke and transient ischemic attack; offers specific treatments for acute ischemic stroke and aneurysmal subarachnoid hemorrhage; provides ways for professionals to prevent first or recurrent stroke; and more. Final chapters of the book discuss rehabilitation after stroke, how patients and carers can be supported in the short term and long term, prevention of recurrent stroke, and the organization of stroke services. Warlow's Stroke: Practical Management, 4th Edition Follows clinical workflow for stroke analysis Features evidence-based approach throughout Offers practical application aimed at improving patient outcomes Written and edited by internationally renowned experts in the field An essential resource for all practitioners involved in the care of patients who suffer from cerebrovascular disease, but particularly suitable for neurologists, residents, geriatricians, stroke physicians, radiologists and primary care physicians.

The Editors Graeme J. Hankey MBBS, MD, FRACP, FRCPE, FAHA, FESO, FAAHMS, Professor of Neurology, Medical School, The University of Western Australia, Perth, Australia; and Consultant Neurologist, Sir Charles Gairdner Hospital, Perth, Western Australia. Malcolm Macleod BSc(Hons), MBChB, PhD, FRCP, Professor of Neurology and Translational Neurosciences at the University of Edinburgh, and Honorary Consultant Neurologist and Head of Neurology, NHS Forth Valley, UK. Philip B. Gorelick MD, MPH, FACP, FAHA, FAAN, FANA, Professor Translational Science and Molecular Medicine at Michigan State University, Grand Rapids, MI, USA; and Adjunct Professor, Davee Department of Neurology, Northwestern Feinberg School of Medicine, Chicago, IL, USA; and International Fellow, Population Health Research Institute affiliated with McMaster University Faculty of Health Sciences and Hamilton Health Sciences, Hamilton, ON, Canada; and Professor Emeritus, Department of Neurology and Rehabilitation, University of Illinois College of Medicine, Chicago, IL, USA. Christopher Chen BA, BMBCh, FRCP, Director, Memory Aging & Cognition Centre, National University Health System, Singapore; and Associate Professor, Department of Pharmacology, National University of Singapore, Singapore; and Senior Consultant Neurologist, Department of Psychological Medicine, National University Hospital, Singapore. Fan Z. Caprio MD, Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. Heinrich Mattle MD, FRCPE, FAHA, FESO, Professor, Senior Consultant, Department of Neurology, University of Bern, Bern, Switzerland.

Contributors vii

Acknowledgments xi

Abbreviations xiii

1 Introduction 1

2 Development of knowledge about cerebrovascular disease 7
Jan van Gijn

3 Is it a vascular event and where is the lesion? 37
Simon Jung and Heinrich P. Mattle

4 Which arterial territory is involved? 129
John C.M. Brust

5 What is the role of imaging in acute stroke? 171

5A Neuroimaging 172
Marwan El-Koussy

5B Ultrasound of the extra- and intracranial arteries 224
Georgios Tsivgoulis and Apostolos Safouris

5C Cardioembolic stroke 241
Issam Mikati and Zeina Ibrahim

6 What caused this transient or persisting ischemic event? 267
Fernando D. Testai

7 Unusual causes of ischemic stroke and transient ischemic attack 345
Fan Z. Caprio and Chen Lin

8 What caused this intracerebral hemorrhage? 399
Farid Radmanesh and Jonathan Rosand

9 What caused this subarachnoid hemorrhage? 437
Matthew B. Maas and Andrew M. Naidech

10 A practical approach to the management of stroke and transient ischemic attack 455
H. Bart van der Worp and Martin Dennis

11 What are this patient's problems? A problem-based approach to the general management of stroke 481
Yannie Soo, Howan Leung, and Lawrence Ka Sing Wong

12 Have the patient's cognitive abilities been affected? 579
Leonardo Pantoni

13 Specific treatment of acute ischemic stroke 587
Eivind Berge and Peter Sandercock

14 Specific treatment of intracerebral hemorrhage 657
Shoichiro Sato and Craig S. Anderson

15 Specific treatment of aneurysmal subarachnoid hemorrhage 679
Gregory Arnone and Sepideh Amin-Hanjani

16 Specific interventions to prevent intracranial hemorrhage 723
Preston W. Douglas, Clio A. Rubinos, and Sean Ruland

17 Preventing recurrent stroke and other serious vascular events 745
Cathra Halabi, Rene Colorado, and Karl Meisel

18 Rehabilitation after stroke: evidence, practice, and new directions 867
Coralie English, Audrey Bowen, Debbie Hébert, and Julie Bernhardt

19 The organization of stroke services 879
Peter Langhorne, Jeyaraj Durai Pandian, and Cynthia Felix

20 Reducing the impact of stroke and improving public health 933
Graeme J. Hankey and Philip B. Gorelick

Index 953

Abbreviations


We don’t care much for abbreviations. They are not literate (Oliver Twist was not abbreviated to OT each time Dickens mentioned his name!), they don’t look good on the printed page, and they make things more difficult to read and understand, particularly for non‐experts. But they do save space and so we have to use them a bit. However, we will avoid them as far as we can in tables, figures and the practice points. We will try to define any abbreviations the first time they are used in each chapter, or even in each section if they are not very familiar. But, if we fail to be comprehensible, then here is a rather long list to refer to.

ACA
Anterior cerebral artery
ACE
Angiotensin‐converting enzyme
AChA
Anterior choroidal artery
ACoA
Anterior communicating artery
ACS
Acute coronary syndrome
ACST
Asymptomatic Carotid Surgery Trial
ADC
Apparent diffusion coefficient
ADH
Antidiuretic hormone
ADL
Activities of daily living
ADP
Adenosine diphosphate
ADPKD
Autosomal dominant polycystic kidney disease
AF
Atrial fibrillation
AFx
Amaurosis fugax
AH
Ataxic hemiparesis
AICA
Anterior inferior cerebellar artery
AIDS
Acquired immune deficiency syndrome
AION
Anterior ischemic optic neuropathy
AMI
Acute myocardial infarction
ANCA
Antineutrophil cytoplasmic antibody
ANF
Antinuclear factor
APS
Antiphospholipid syndrome
APT
Antiplatelet Trialists’ Collaboration
APTT
Activated partial thromboplastin time
ARAS
Ascending reticular activating system
ARB
Angiotensin II receptor (AT1) blockers
ARD
Absolute risk difference
ASA
Atrial septal aneurysm
ASD
Atrial septal defect
ATIII
Antithrombin III
ATP
Adenosine triphosphate
ATT
Antithrombotic Trialists’ Collaboration
AVF
Arteriovenous fistula
AVM
Arteriovenous malformation
BA
Basilar artery
BAD
Branch atheromatous plaque disease
BIH
Benign intracranial hypertension
BMI
Body mass index
BOLD
Blood oxygenation level‐dependent
BP
Blood pressure
C
Celsius
CAA
Cerebral amyloid angiopathy
CADASIL
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy
CARASAL
Cathepsin A related arteriopathy with strokes and leukoencephalopathy
CARASIL
Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy
CAST
Chinese Acute Stroke Trial
CAVATAS
Carotid and Vertebral Artery Transluminal Angioplasty Study
CBF
Cerebral blood flow
CBFV
Cerebral blood flow velocity
CBV
Cerebral blood volume
CCA
Common carotid artery
CDU
Carotid duplex
CEA
Carotid endarterectomy
CE‐MRA
Contrast‐enhanced MR angiography
CHD
Coronary heart disease
CI
Confidence interval
CJD
Creutzfeldt–Jakob disease
CK
Creatine kinase
CMB
Cerebral microbleed
CMRO2
Cerebral metabolic rate of oxygen
CMRglu
Cerebral metabolic rate of glucose
CNS
Central nervous system
COX 2
Cyclo‐oxygenase 2 inhibitors
CPP
Cerebral perfusion pressure
CPSP
Central post‐stroke pain
CSF
Cerebrospinal fluid
CT
Computed tomography
CTA
Computed tomography angiography
CTP
Cerebral perfusion imaging with CT
CTP
Computed tomography perfusion
CVR
Cerebrovascular resistance
CVST
Cerebral venous sinus thrombosis
DALY
Disability‐adjusted life year
DAVF
Dural arteriovenous fistula
DBP
Diastolic blood pressure
DCHS
Dysarthria clumsy‐hand syndrome
DIC
Disseminated intravascular coagulation
DNA
Deoxyribose nucleic acid
DOAC
Direct oral anticoagulants
DPM
Diffusion‐perfusion mismatch
DSA
Digital subtraction angiography
DSC
Dynamic susceptibility contrast
DSM
Diagnostic and statistical manual of mental disorders
DVT
Deep venous thrombosis (in the legs or pelvis)
DWI
Diffusion‐weighted (MR) imaging
EACA
Epsilon‐aminocaproic acid
EADL
Extended activities of daily living
EAFT
European Atrial Fibrillation Trial
ECA
External carotid artery
ECASS
European Cooperative Acute Stroke Study
ECG
Electrocardiogram
EC‐IC
Extracranial–intracranial
ECST
European Carotid Surgery Trial
EEG
Electroencephalogram
EMG
Electromyography
ESR
Erythrocyte sedimentation rate
FAST
Face‐Arm‐Speech Test
FAT‐SAT
Fat saturation sequences
FDA
Food and Drug Administration
FIM
Functional Independence Measure
FLAIR
Fluid attenuated inversion recovery
FMD
Fibromuscular dysplasia
fMRI
Functional magnetic resonance imaging
FMZ
Flumazenil
GCS
Glasgow Coma Scale
GEF
Glucose extraction fraction
GKI
Glucose, potassium and insulin
GRE
Gradient‐recalled echo
HACP
Homolateral ataxia and crural paresis
Hg
Mercury
HI
Hemorrhagic infarction
HIT
Heparin‐induced thrombocytopenia
HITS
High intensity transient signals
HIV
Human immunodeficiency virus
HMPAO
Hexamethylpropyleneamine oxime
HTI
Hemorrhagic transformation of an infarct
HU
Hounsfield units
IAA
Internal auditory artery
IAA
Intra‐arterial angiography
IAT
Intra‐arterial treatment
IC
Infarct core
ICA
Internal carotid artery
ICH
Intracerebral hemorrhage
ICIDH
International Classification of Impairments, Disabilities and Handicaps
ICP
Intracranial pressure
ICVT
Intracranial venous thrombosis
IADSA
Intra‐arterial digital subtraction angiography
INR
International normalized ratio
IST
International Stroke Trial
IVDSA
Intravenous digital subtraction angiography
IVIG
Intravenous immunoglobulins
IVIM
Intravoxel incoherent motion
IVM
Intracranial vascular malformation
kPa
Kilopascals
L
Litre
LAA
Left atrial appendage
LACI
Lacunar infarction
LACS
Lacunar syndrome
LGN
Lateral geniculate nucleus
LP
Lumbar puncture
LSA
Lenticulostriate artery
M
Molar
MAC
Mitral annular calcification
MAOI
Monoamine oxidase inhibitor
MAST‐I
Multicentre Acute Stroke Trial – Italy
MCA
Middle cerebral artery
MCTT
Mean cerebral transit time
MELAS
Mitochondrial encephalopathy, lactic acidosis, and stroke‐like episodes
MES
Microembolic signals
MFV
Mean flow velocities
MI
Myocardial infarction
MLF
Medial longitudinal fasciculus
MLP
Mitral leaflet prolapse
MMSE
Mini mental state examination
MND
Motor neuron disease
MR
Magnetic resonance
MRA
Magnetic resonance angiography
MRC
Medical Research Council
MRI
Magnetic resonance imaging
MRS
Magnetic resonance spectroscopy
MRV
Magnetic resonance venogram
MTT
Mean transit time
NAA
N‐acetyl aspartate
NASCET
North American Symptomatic Carotid Endarterectomy Trial
NCCT
Noncontrast CT
NELH
National Electronic Library for Health
NG
Nasogastric
NIHSS
National Institutes of Health Stroke Score
NINDS
National Institute of Neurological Disorders and Stroke
NIRS
Near infrared spectroscopy
NNT
Number‐needed‐to‐treat
NO
Nitric oxide
NSAID
Nonsteroidal anti‐inflammatory drug
OA
Ophthalmic artery
OCSP
Oxfordshire Community Stroke Project
OCP
Oral contraceptive
OEF
Oxygen...

Erscheint lt. Verlag 28.1.2019
Sprache englisch
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Neurologie
Naturwissenschaften Biologie
Schlagworte Biowissenschaften • Brain Haemorrhage • brain hemorrhage • cerebrovascular disease • danger of stroke • diagnosing stroke • diagnosing stroke events • guide to strokes • intercranial hemorrhage • Life Sciences • Medical Science • Medizin • Neurologie • Neurology • Neuroscience • Neurovascular Disease • Neurovaskuläre Krankheiten • Neurowissenschaften • Preventing stroke • preventing stroke events • preventing strokes • prevent intracranial haemorrhage • providing rehabilitation for stroke patients • stroke • stroke and other vascular events • stroke events • Stroke Management • stroke prevention • treating stroke events • treating stroke patients • types of stroke events • types of vascular events
ISBN-10 1-118-49241-2 / 1118492412
ISBN-13 978-1-118-49241-3 / 9781118492413
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