Hepatitis B Virus and Liver Disease

Jia-Horng Kao, Ding-Shinn Chen (Herausgeber)

Buch | Softcover

360 Seiten

2019 | Softcover reprint of the original 1st ed. 2018
Springer Verlag, Singapore
978-981-13-5245-4 (ISBN)

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This book provides a comprehensive, state-of-the art review of HBV infection and liver disease. It discusses new data on basic and translational medicine, including the viral life cycle, the immunopathogenesis of virus-induced chronic hepatitis, viral and host genetic factors affecting disease progression, and the mechanism of virus-induced hepatocarcinogenesis, as well as their potential applications in daily clinical practice. The clinical aspects of chronic HBV infection are examined in chapters on the global epidemiology, efficacy of HBV vaccination, natural history, co-infections with HCV, HDV or HIV, and management of special populations including children, pregnant women and patients undergoing immunosuppressive therapy. Further, it describes the advances and perspectives in the development of novel antiviral treatments as possible cures for HBV infection. The book is a valuable resource for medical students, physicians, and researchers who are interested in managem

ent of patients with chronic HBV infection and investigation of HBV infection.

Editor Jia-Horng Kao is a Professor at the Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan. Professor Ding-Shinn Chen is a Professor at the Genomics Research Center, and the Academician of Academic Sinica, Taipei, Taiwan.

Life cycle and molecular virology.- Unmet needs in basic research: in vitro and in vivo models.- Immunopathogenesis.- Epidemiology and natural history.- Hepatitis B vaccination.- Viral factors and disease progression.- Host genetic factors and disease progression.- Molecular carcinogenesis of HCC.- Interferon therapy and long-term outcomes.- Nucleotide therapy and long-term outcomes.- Combination therapy.- Treatment of patients with HCV, HDV or HIV co-infection.- Management of children and pregnant women.- Management of patients with immunosuppressive therapy.- Towards an HBV cure: discovery of novel agents.- Others: occult HBV infection.

“The purpose is to present updated information regarding the pathogenesis, epidemiology, and prevention of hepatitis B, with a strong emphasis on basic and translational medicine. The audience includes students, healthcare providers, and researchers interested in hepatitis B or who wish to stay up to date in this area. The book would be of the greatest benefit to research‐oriented readers and/or those working in geographic areas highly endemic in hepatitis B.” (Cezarina Mindru, Doody's Book Reviews, April, 2018)

Erscheinungsdatum	11.03.2019
Zusatzinfo	29 Illustrations, color; 11 Illustrations, black and white
Verlagsort	Singapore
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Medizinische Fachgebiete ► Innere Medizin ► Hepatologie
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Mikrobiologie / Infektologie / Reisemedizin
	Studium ► Querschnittsbereiche ► Infektiologie / Immunologie
	Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie
Schlagworte	Chronic Hepatitis • HBV • Hepatitis B Virus • hepatocellular carcinoma • Immunopathogenesis • Immunosuppressive therapy • liver cirrhosis
ISBN-10	981-13-5245-3 / 9811352453
ISBN-13	978-981-13-5245-4 / 9789811352454
Zustand	Neuware