Biology of Chlamydia

Buch | Hardcover

X, 237 Seiten

2018
Springer International Publishing (Verlag)
978-3-319-71230-7 (ISBN)

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The genus Chlamydia encompasses a number of species of obligate intracellular bacteria, including important human pathogens like the most common bacterial agent of sexually transmitted disease. This volume reviews current knowledge of chlamydial biology, covering the unusual structure of the bacteria - which alternate between metabolically almost inactive and fast-dividing forms. It also discusses the ways in which Chlamydia manipulates the host cytoskeleton and subverts the host cell's defence, and illustrates how genomics have begun to uncover the diversity and complexity of chlamydial strains that look very similar but may cause distinct forms of disease. Further, it describes how techniques are now finally being established that can genetically modify Chlamydia, and discusses why such modification is still very difficult and what progress we can expect. Lastly, it presents our current understanding of chlamydial disease: what do we know about chronic infections, what are the mechanisms of inflammatory damage, and what are the prospects of a vaccine? Written be specialists in these various areas, the book is a valuable work of reference for students and scientists with an interest in the molecular, cellular and immunobiology of these fascinating bacteria.

Prof. Dr. med. Georg Häcker Universitätsklinikum Freiburg Institut für Medizinische Mikrobiologie und Hygiene Hermann-Herder-Str. 11 79104 Freiburg Germany e-mail: Georg.Haecker@uniklinik-freiburg.de Phone: +49 761 203-6531

Cell wall biosynthesis in Chlamydia.- Genetic manipulation in Chlamydia.- Early events in the Chlamydia developmental cycle.- Subversion of the host cell cytoskeleton by Chlamydia.- Cell-autonomous host defence against Chlamydia infection.- The enigma of long-term infection: are there quiescent or 'persistent' Chlamydia?- Mechanisms of immunopathogenesis during chlamydial infections.- Protective adaptive immune response and prospects for a vaccine.- The hidden genomics of Chlamydia trachomatis.

Erscheinungsdatum	26.03.2018
Reihe/Serie	Current Topics in Microbiology and Immunology
Zusatzinfo	X, 237 p.
Verlagsort	Cham
Sprache	englisch
Maße	155 x 235 mm
Gewicht	537 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Mikrobiologie / Infektologie / Reisemedizin
	Studium ► Querschnittsbereiche ► Infektiologie / Immunologie
	Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie
Schlagworte	cell wall biosynthesis • Chlamydia developmental cycle • Chlamydia infections • Chlamydia pneumonia • Chlamydia trachomatis • Infectious Diseases • Peptidoglycan
ISBN-10	3-319-71230-6 / 3319712306
ISBN-13	978-3-319-71230-7 / 9783319712307
Zustand	Neuware