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Protein-Protein Interactions in Human Disease, Part A

Buch | Hardcover

288 Seiten

2018
Academic Press Inc (Verlag)
978-0-12-814344-5 (ISBN)

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Protein-Protein Interactions in Human Disease, Part A, Volume 110 aims to promote further research and development in the protein interaction network as a means to not only identify the critical proteins involved in the etiology of human diseases, but also identify new protein targets for drug development. Sections cover such topics as protein-protein interaction modulators for epigenetic therapies, intrinsic disorder, protein-protein interactions and disease, targeting protein-protein interactions in the ubiquitin-proteasome pathway, the proteomics of occupational diseases, and computational methods in predicting the impact of SNPs in protein-protein network, amongst other topics.

Rossen Donev received his PhD degree in 1999 from the Institute of Molecular Biology, Bulgarian Academy of Sciences. He did postdoctoral training at Imperial Cancer Research Fund, UK (renamed after the merger with Cancer Research Campaign to Cancer Research UK, London Research Institute) and Cardiff University. In 2007 he was awarded a New Investigator Grant Award from the Medical Research Council (UK) to establish himself as an independent Principle Investigator. In 2010 Dr. Donev was appointed Senior Lecturer at Swansea University. In 2016 Dr. Donev joined MicroPharm Ltd (UK) where currently he is Head of Research. He has published more than 60 research papers, chaired scientific meetings and given invited plenary talks. Rossen Donev has consulted on projects related to development of treatments for neurodevelopmental disorders and cancer therapies. He serves as Editor-in-Chief of the Advances in Protein Chemistry and Structural Biology and on editorial board of several other journals. His research interests include signaling pathways involved in neuropsychiatric disorders and tumor escape from the immune system, and development of therapeutic strategies for their treatment. More recently he has focused on development of immunotherapeutics for non-systemic applications.

1. Analysis of protein interactions by surface plasmon resonance
Dennis G. Drescher
2. Using TR-FRET to investigate protein-protein interactions: a case study of PXR-coregulator interaction
Taosheng Chen
3. Protein-Protein Interaction Modulators for Epigenetic Therapies
Jose L. Medina-Franco
4. Intrinsic disorder, protein-protein interactions and disease
Vladimir N. Uversky
5. Targeting protein-protein interactions in the ubiquitin-proteasome pathway
Maria Gaczynska
6. Protein-protein networks involved in MODY family
George Priya Doss P. C
7. Defining HIV-1 replication mechanisms by analyzing virus-host protein interactions
Manuel Llano
8. Proteomics of occupational diseases
Nicola Luigi Bragazzi
9. Proteomics of sport-related injuries
Nicola Luigi Bragazzi
10. Structural prediction of protein-protein interactions by docking: application to biomedical problems
Juan Fernandez-Recio
11. Computational methods in predicting the impact of SNPs in Protein-protein network
George Priya Doss P. C

Erscheinungsdatum	10.02.2018
Reihe/Serie	Advances in Protein Chemistry and Structural Biology
Verlagsort	San Diego
Sprache	englisch
Maße	152 x 229 mm
Gewicht	610 g
Themenwelt	Naturwissenschaften ► Biologie ► Biochemie
ISBN-10	0-12-814344-4 / 0128143444
ISBN-13	978-0-12-814344-5 / 9780128143445
Zustand	Neuware