Peptide-Mediated Biomineralization (eBook)

JOSE ISAGANI B. JANAIRO (Autor)

eBook Download: PDF

2016 | 1st ed. 2016
VIII, 64 Seiten
Springer Singapore (Verlag)
978-981-10-0858-0 (ISBN)

Infos

This book describes recent advances in peptide-mediated biomineralization and how this method was able to create improved catalysts through minor tweaks in the system. The book is thorough in its discussion which will be appreciated by beginners such as advanced undergraduate students. The topics covered are very recent which will raise the interest of experts. The book is envisioned to become a 'one-stop-shop' for peptide mediated biomimetic material synthesis by discussing the most recent and most relevant topics related to biomineralization. The book attempts to discuss biomineralization from different perspectives in order to provide a multi-disciplinary treatment to the subject. Aside from being a reference material, this book can also serve as a manual to guide researchers engaged in the field since the chapters contain sections describing experimental procedures. The book also contains high quality illustrations and images that will surely add depth and clarity in the discussion.



Dr. Jose Isagani Janairo received his BS Biochemistry (cum laude) and MS Chemistry degrees at De La Salle University-Manila. He earned his Doctorate degree at the age of 26 as a Monbukagakusho scholar at Hokkaido University for his work about bionanotechnology. His work was featured as one of the cover articles for the journal Chemical Communications and as an Editor's Choice Paper for Chemistry Letters. During the course of his studies, Dr. Janairo received awards and recognitions from ASEAN, Hokkaido University, Chemical Society of Japan, Japanese Biochemical Society, Japan Society for the Promotion of Science and the Clark Memorial Foundation. Currently, the research interest of Dr. Janairo involves biomaterial science, molecular modelling and chemical ecology.

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This book describes recent advances in peptide-mediated biomineralization and how this method was able to create improved catalysts through minor tweaks in the system. The book is thorough in its discussion which will be appreciated by beginners such as advanced undergraduate students. The topics covered are very recent which will raise the interest of experts. The book is envisioned to become a "e;one-stop-shop"e; for peptide mediated biomimetic material synthesis by discussing the most recent and most relevant topics related to biomineralization. The book attempts to discuss biomineralization from different perspectives in order to provide a multi-disciplinary treatment to the subject. Aside from being a reference material, this book can also serve as a manual to guide researchers engaged in the field since the chapters contain sections describing experimental procedures. The book also contains high quality illustrations and images that will surely add depth and clarity in the discussion.

Inhalt

Preface 6
Contents 8
1 Introduction to Peptide Chemistry and Materials Characterization 10
Abstract 10
1.1 Solid-phase Peptide Synthesis 10
1.1.1 The Solid Support 11
1.1.1.1 Types of Solid Support 12
1.1.2 Amino Acid Protecting Groups 16
1.1.2.1 Types of Protecting Groups 16
1.1.3 Activation and Coupling 18
1.1.4 Coupling Reagents 18
1.2 Characterization 21
1.2.1 Circular Dichroism (CD) Spectroscopy 21
1.2.2 The Electron Microscope and Electron–Matter Interaction 22
References 23
2 Biomineralization and the Sequence: Function Effects on the Peptide 27
Abstract 27
2.1 Introduction 27
2.1.1 Biomineralization as a Natural Phenomenon 27
2.1.2 Biomineralization as a Synthetic Route Towards Nanomaterial Synthesis 28
2.1.3 Biomineralization Peptide Discovery 30
2.2 Peptide-dependent Factors Influencing Biomineralization 31
2.2.1 Amino Acid Composition and Sequence 31
2.2.2 Conformation 34
2.2.3 Post-translational Modification 35
2.3 Case Study 37
2.3.1 Uncovering Sequence-based Relationships Among Biomineralization Peptides 37
References 41
3 Synergistic Approaches in Creating Functional Nanomaterials: Fusion Peptides and Bimetallic Nanostructures 44
Abstract 44
3.1 Introduction 44
3.2 Structural Control Elements for Biomineralization Peptides 45
3.2.1 Viruses 45
3.2.2 Peptides and Proteins 46
3.2.3 Small Organic Molecules 47
3.3 Peptide-mediated Biomineralization of Bimetallic Nanomaterials 48
3.4 Case Study: Controlling the Geometry, Spatial Orientation, and Valency of a Biomineralization Peptide Using the Tetramerization Domain of the Tumor Suppressor p53 Protein 50
References 57
4 Enhanced Nanomaterials Through Simple Tweaks in the Microenvironment 60
Abstract 60
4.1 Introduction 60
4.2 Microenvironment Conditions Affecting Biomineralization 61
4.2.1 Metal Stoichiometry 61
4.2.2 Reductant 62
4.2.3 pH 64
4.2.4 Buffer Type 66
4.3 Case Study 67
4.3.1 Systematic Analysis of the Effects of Buffer on Palladium Biomineralization 67
References 71

Produkt-Details

• Erscheint lt. Verlag: 29.4.2016
• Reihe/Serie: SpringerBriefs in Materials
• Reihe/Serie: SpringerBriefs in Materials
• Zusatzinfo: VIII, 64 p. 7 illus., 4 illus. in color.
• Verlagsort: Singapore
• Sprache: englisch
• Themenwelt: Naturwissenschaften ► Biologie ► Biochemie
• Themenwelt: Naturwissenschaften ► Chemie ► Organische Chemie
• Themenwelt: Technik ► Maschinenbau
• Schlagworte: Bimetallic Nanomaterials • Biomimetic materials • Catalytic Nanomaterials • Functional Nanomaterials • Peptide Self-Assembly
• ISBN-10: 981-10-0858-2 / 9811008582
• ISBN-13: 978-981-10-0858-0 / 9789811008580