Activation-Induced Deaminase

On the Targeting Mechanism of AID to the Immunoglobulin Loci

Andrew Franklin (Autor)

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XX, 120 Seiten | Ausstattung: Hardcover & eBook

2019
De Gruyter
978-3-11-046075-9 (ISBN)

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The mechanism of hypermutation, the process needed for B cell affinity maturation, is one of the last great mysteries in molecular biology. Activation-induced deaminase (AID) is absolutely required for hypermutation, but the mechanism by which it is recruited specifically to antibody-encoding genes remains enigmatic. This book summarizes the research on AID in the context of its central role in the affinity maturation of B cells.

Andrew Franklin, Berlin, Germany.

Zusatzinfo	Includes a print version and an ebook
Verlagsort	Berlin
Sprache	englisch
Maße	240 x 170 mm
Themenwelt	Naturwissenschaften ► Biologie
Schlagworte	Affinity maturation • Antibody • B cells • hypermutation • immune response
ISBN-10	3-11-046075-0 / 3110460750
ISBN-13	978-3-11-046075-9 / 9783110460759
Zustand	Neuware