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Adipose Tissue and Adipokines in Health and Disease -

Adipose Tissue and Adipokines in Health and Disease (eBook)

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2014 | 2nd ed. 2014
XXVI, 372 Seiten
Humana Press (Verlag)
978-1-62703-770-9 (ISBN)
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The field of adipose tissue biology has been expanding at a very rapid pace in the last few years. Numerous advances have been made since publication of the first edition of this book, in terms of basic adipocyte biology, understanding of the determinants of obesity, distribution of body fat and weight loss, as well as the mechanisms linking excess adiposity to various co-morbidities.  Adipose Tissue and Adipokines in Health and Disease, Second Edition contains updated chapters from the previous volume but as the field has evolved, some areas covered in the first edition have been refocused to address the new knowledge.  The volume is divided in four sections:  the first two deal with basic adipose tissue and adipokine biology, while the last two address the problem of obesity and alterations in adipose tissue function from an epidemiological and clinical standpoint.  The chapters are written by experts in their fields and include the most up to date scientific information.  Adipose Tissue and Adipokines in Health and Disease, Second Edition is a useful resource for physicians interested in adipose tissue biology and basic scientists who want to know more about applied aspects of the field.  The book targets endocrinologists, residents and fellows, internists, nutritionists and general practitioners who are exposed to an ever-expanding obese population.

Dr. Giamila Fantuzzi is a Professor in the Department of Kinesiology and Nutrition at the University of Illinois at Chicago. From 2000 to 2004 she was an Assistant Professor in the Department of Medicine at the University of Colorado Health Sciences Center.

Dr. Fantuzzi is a graduate of the University of Milano, Italy, where she obtained a PhD in Experimental Endocrinology. She completed her post-doctoral fellowships in the laboratory of Neuroimmunology at the Mario Negri Institute for Pharmacological Research in Milano, Italy and in the Division of Geographic Medicine and Infectious Diseases at the New England Medical Center of Tufts University in Boston, MA.

Dr. Fantuzzi has published extensively on the role of cytokines, adipokines and adipose tissue in the regulation of inflammation. Her current research focuses on the role of adipose tissue in regulating inflammation in the pancreas and the gastrointestinal tract. Her research is currently funded by the National Institutes of Health and she received past funding from the Cystic Fibrosis Foundation, the Crohn's and Colitis Foundation of America, the Broad Medical Research Program and the National Pancreas Foundation. Dr. Fantuzzi is an active member of several scientific societies and serves as an appointed member of the Tumor Microenvironment Study Section of the US Center for Scientific Review.

Dr. Carol Braunschweig is a Professor and Associate Head in the Department of Kinesiology and Nutrition at the University of Illinois at Chicago. Dr. Braunschweig received her BS and MS in Nutrition at Michigan State University and her PhD in Epidemiology at the University of Michigan. Prior to her work in academia she was a nutrition support specialist in the Department of Pharmacy at the University of Michigan. Dr Braunschweig's current research focuses on the role of nutritional intake and body composition on disease risks and outcomes in diverse populations including minority, disabled, children and hospitalized patients.  Her research is currently funded by the National Institutes of Health and she received past funding from the American Cancer Society, Center for Disease Control and the Department of Health and Human Services.  She is an active member of several scientific societies and is also the Director of Clinical Nutrition, UIC Center for Clinical and Translational Sciences.


The field of adipose tissue biology has been expanding at a very rapid pace in the last few years. Numerous advances have been made since publication of the first edition of this book, in terms of basic adipocyte biology, understanding of the determinants of obesity, distribution of body fat and weight loss, as well as the mechanisms linking excess adiposity to various co-morbidities. Adipose Tissue and Adipokines in Health and Disease, Second Edition contains updated chapters from the previous volume but as the field has evolved, some areas covered in the first edition have been refocused to address the new knowledge. The volume is divided in four sections: the first two deal with basic adipose tissue and adipokine biology, while the last two address the problem of obesity and alterations in adipose tissue function from an epidemiological and clinical standpoint. The chapters are written by experts in their fields and include the most up to date scientific information. Adipose Tissue and Adipokines in Health and Disease, Second Edition is a useful resource for physicians interested in adipose tissue biology and basic scientists who want to know more about applied aspects of the field. The book targets endocrinologists, residents and fellows, internists, nutritionists and general practitioners who are exposed to an ever-expanding obese population.

Dr. Giamila Fantuzzi is a Professor in the Department of Kinesiology and Nutrition at the University of Illinois at Chicago. From 2000 to 2004 she was an Assistant Professor in the Department of Medicine at the University of Colorado Health Sciences Center. Dr. Fantuzzi is a graduate of the University of Milano, Italy, where she obtained a PhD in Experimental Endocrinology. She completed her post-doctoral fellowships in the laboratory of Neuroimmunology at the Mario Negri Institute for Pharmacological Research in Milano, Italy and in the Division of Geographic Medicine and Infectious Diseases at the New England Medical Center of Tufts University in Boston, MA. Dr. Fantuzzi has published extensively on the role of cytokines, adipokines and adipose tissue in the regulation of inflammation. Her current research focuses on the role of adipose tissue in regulating inflammation in the pancreas and the gastrointestinal tract. Her research is currently funded by the National Institutes of Health and she received past funding from the Cystic Fibrosis Foundation, the Crohn’s and Colitis Foundation of America, the Broad Medical Research Program and the National Pancreas Foundation. Dr. Fantuzzi is an active member of several scientific societies and serves as an appointed member of the Tumor Microenvironment Study Section of the US Center for Scientific Review. Dr. Carol Braunschweig is a Professor and Associate Head in the Department of Kinesiology and Nutrition at the University of Illinois at Chicago. Dr. Braunschweig received her BS and MS in Nutrition at Michigan State University and her PhD in Epidemiology at the University of Michigan. Prior to her work in academia she was a nutrition support specialist in the Department of Pharmacy at the University of Michigan. Dr Braunschweig’s current research focuses on the role of nutritional intake and body composition on disease risks and outcomes in diverse populations including minority, disabled, children and hospitalized patients.  Her research is currently funded by the National Institutes of Health and she received past funding from the American Cancer Society, Center for Disease Control and the Department of Health and Human Services.  She is an active member of several scientific societies and is also the Director of Clinical Nutrition, UIC Center for Clinical and Translational Sciences.

Part I. Adipose Tissue: Structure and Function 1.       Adipose Tissue in Evolution – Karin Isler 2.       Adipose Stem Cells and Adipogenesis – Yourka D. Tchoukalova and Ursula A. White  3.       Metabolism of White Adipose Tissue – Michel Beylot   4.       Bad Fat or Just More Fat? Murine Models of Metabolically-Healthy Obesity – Grace Bennett, Andrew S. Greenberg, and Martin S. Obin 5.       The Aging Adipose Organ: Lipid Redistribution, Inflammation, and Cellular Senescence –  James L. Kirkland, Michael B. Stout, and Tamara Tchkonia 6.       Adipokines: Leptin and Adiponectin in the regulation of inflammatory and immune responses –  Giamila Fantuzzi   Part II. Adipose Tissue Inflammation and Adipocyte Dysfunction in Obesity 7.       Adipose Tissue Inflammation – Verena Wieser, Alexander R. Moschen, and Herbert Tilg 8.       Endoplasmic Reticulum Stress and Adipose Tissue Function – Michael Pagliassotti, Gretchen Moran, Andrea Estrada, and Michelle T. Foster9.       Autophagy in White Adipose Tissue – Scott G. Goldman, Hanlin Tao, and Shengkan `Victor’ Jin 10.   Obesity and Micronutrient Deficiencies – Lisa Tussing-Humphrey and Van T.Q. Nguyen Part III. Obesity 11.   Epidemiology of Obesity in Children – Youfa Wang and Hyunjung Lim 12.   Genetics of Obesity –  Beatrice Dubern and Patrick Tounian 13.   Epigenetics of Obesity – Simonetta Friso and Sang-Woon Choi 14.   Consequences of Rapid Weight Loss – Niu Zhang, Irene Lo, and Ashutosh Kaul Part IV. Adipose Tissue and Disease 15.   Human Lipodystrophy: An Update on Molecular Genetics and Possible Mechanisms of Fat Loss –  Anil  K. Agarwal 16.   Adipose Tissue and Type 2 Diabetes Mellitus – Bernardo Léo Wajchenberg and Ricardo V. Cohen 17.   Adipokines in Non-Alcoholic Fatty Liver Disease – Ancha Barranova, Aybike Biererdinc, and Zobair M. Younossi  18.   Obesity and Cardiovascular Disease  –  Edmond Obeng-Gyimah and Flora Sam 19.   Respiratory Diseases in Obesity – David G. Chapman, Benjamin T. Surett, and Anne E. Dixon 20.   Adiposity & Kidney Disease – Josephine D. Abraham and Srinavasan Beddhu  21.   Obesity and Joint Disease – Yuan Z. Lim, Anita E. Wluka, Yuanyuan Wang, and Flavia M. Cicuttini 22.   Obesity and Colon and Postmenopausal Breast Cancer –  Patricia M. Sheean, Sandra L. Gomez-Perez, Puja Agarwal, & Carol Braunschweig

Erscheint lt. Verlag 25.4.2014
Reihe/Serie Nutrition and Health
Zusatzinfo XXVI, 372 p. 38 illus., 25 illus. in color.
Verlagsort Totowa
Sprache englisch
Themenwelt Medizin / Pharmazie Allgemeines / Lexika
Medizin / Pharmazie Gesundheitsfachberufe Diätassistenz / Ernährungsberatung
Medizinische Fachgebiete Innere Medizin Endokrinologie
Studium 1. Studienabschnitt (Vorklinik) Biochemie / Molekularbiologie
Naturwissenschaften Biologie
Technik
Schlagworte Adipocyte • Adipokines • Adipose tissue • Diabetes • endocrinology • lipodystrophy • Obesity
ISBN-10 1-62703-770-5 / 1627037705
ISBN-13 978-1-62703-770-9 / 9781627037709
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