The Steric Factor in Medicinal Chemistry

Dissymmetric Probes of Pharmacological Receptors

A.F. Casy (Autor)

Buch | Softcover

570 Seiten

2013 | Softcover reprint of the original 1st ed. 1993
Springer-Verlag New York Inc.
978-1-4899-2399-8 (ISBN)

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'It is indeed the merit of Dr. Alan F. Casy to bring in these pages a clear and comprehensive view of medicinal stereochemistry, a discipline in which he has been active and successful for many years both as a teacher and a researcher. Written for graduate students and research workers in medicinal chemistry and pharmacology, this book will contribute significantly towards a better education of scientists by removing the fear of stereochemistry caused by ignorance, moderating the overconfidence of possible zealots, and outlining a broader context.'-from the foreword by Bernard Testa

1. Introduction.- 2. Nomenclature and Methodology.- 3. Pharmacokinetics: Including Use of Racemic Mixtures in Therapy.- 4. Adrenergic Ligands: Chiefly Agonists.- 5. Adrenoceptor Antagonists.- 6. Dopamine and Dopaminergic Ligands.- 7. Dopamine Antagonists.- 8. Cholinergic Agonists.- 9. Muscarinic Antagonists.- 10. Ligands of Nicotinic Cholinergic Receptors (nAChR) Including Neuromuscular Blocking Agents.- 11. Histamine Receptors: Agonists and Antagonists.- 12. 5-Hydroxytryptamine Ligands.- 13. Opioid Ligands: Part 1.- 14. Opioid Ligands: Part 2.- Appendix and Postscript.

Zusatzinfo	XX, 570 p.
Verlagsort	New York
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
	Medizin / Pharmazie ► Pharmazie
	Medizin / Pharmazie ► Studium
	Naturwissenschaften ► Biologie ► Biochemie
	Naturwissenschaften ► Chemie ► Organische Chemie
	Naturwissenschaften ► Chemie ► Physikalische Chemie
ISBN-10	1-4899-2399-3 / 1489923993
ISBN-13	978-1-4899-2399-8 / 9781489923998
Zustand	Neuware