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Structural Biology of Membranes

Buch | Hardcover
470 Seiten
2021 | 1st ed. 2021
Springer Verlag, Japan
978-4-431-54131-8 (ISBN)
CHF 224,60 inkl. MwSt
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The book describes the three-dimensional structural features of the molecules underlying the physiologic functions of biologic membranes, as well as other crucially important functions, further enhancing and deepening the understanding of biologic function.
The volume describes the three-dimensional structural features of the molecules underlying the physiologic functions of biologic membranes. While this book has a rather clear focus on the membrane, as a major component of any cell, it will also cover the other crucially important functions within cells, further enhancing and deepening the understanding of biologic function. This knowledge is believed to be vital in the development of new pharmaceutical modalities, given that almost 50% of drug targets are thought to be membrane proteins. This book is designed to be a reference text for a broad range of readers, from researchers in a variety of scientific and related medical fields, to graduate students working in these specialties.

1) Construction of cells and importance of membrane proteins 2) Lipid bilayer and lipid molecules 3) Channels a) ion channels a-1) K+ channels a-2) Na+ channels a-3) Ca2+ channels a-4) Voltage-sensitive channels a-5) Ligand gated channels a-6) Mechanosensitive channels a-7) Other ion channels b) Water channels b-1) Aquaporin-0 b-2) Aquaporin-1 b-3) Aquaporin-2 b-4) Aquaporin-3 b-5) Aquaporin-4 b-6) Aquaporin-5 b-7) Aquaporin-6 b-8) Aquaporin-7 b-9) Aquaporin-8 b-10) Aquaporin-9 b-11) Aquaporin-10 b-12) Aquaporin-11and Aquaporin-12 b-13) Other water channels c) Gap junction channels d) Porins e) Other channels 4) Receptors a) G protein-coupled receptors a-1) Rhodopsin a-2) GPCRs of non-peptidic ligand; b1 aderenergic receptor, b2 adrenergic receptor, A2 adrenergic receptor, Muscarinic Acetylcholine receptors a-3) GPCRs of peptidic ligand; Chemokine receptors, Endothelin receptors a-4) Sygnal transduction by GPCRs b) Ionotropic receptors b-1) AMPA receptors b-2) NMDA receptors b-3) Acetylcholine receptors c) IP3 receptors d) P2X family proteins e) Photo receptors and Photosynthesis f) Other receptors 5) Transporters and pumps a) P-type ATPases b) V-type ATPases c) F-type ATPases d) ABC transporters e) Ion transporters f) Syn-porters and Anti-porters g) Proton pumps h) Nuclear pore complexes i) Translocators j) Other transporters and pumps 6) Motors a) Flagella b) Cilia c) Other motors 7) Enzymes a) Enzymes for lipid modification a-1) Prostaglandins a-2) Microsomal glutathione synthetase (S-transferases) a-3) Leukotriene synthase b) Enzyme-coupled cell signaling b-1) Tyrosine Kinases b-2) Proteolysis of membrane proteins c) Other enzymes 8) Adhesive molecules a) Cadherins b) Integrins c) Neuroligin-Neurexin d) Claudin e) Nectine f) Other adhesive molecules g) Fusion proteins 9) Membrane dynamics a) Cell division b) Growth cone c) Caveolins d) Synapses e) Blebs f) Cell migration g) Endocytosis and Exocytosis h) Cell death i) Immune system j) Cancer cells k) Cell differentiation l) Characteristics of stem cells 10) Structural physiology of biologic membranes 11) Structural views of living organisms

Erscheint lt. Verlag 13.6.2021
Zusatzinfo 100 Illustrations, color; XVIII, 470 p. 100 illus. in color.
Verlagsort Tokyo
Sprache englisch
Maße 155 x 235 mm
Themenwelt Naturwissenschaften Biologie Biochemie
Naturwissenschaften Biologie Mikrobiologie / Immunologie
Naturwissenschaften Biologie Zellbiologie
Schlagworte Channels • GPCR • Membranes • Physiology • receptors • Structure
ISBN-10 4-431-54131-4 / 4431541314
ISBN-13 978-4-431-54131-8 / 9784431541318
Zustand Neuware
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