Copper–Mediated Cross–Coupling Reactions

Gwilherm Evano, Nicolas Blanchard (Autoren)

Software / Digital Media

840 Seiten

2013
John Wiley & Sons Inc (Hersteller)
978-1-118-69065-9 (ISBN)

Infos

Providing comprehensive insight into the use of copper in cross-coupling reactions, Copper-Mediated Cross-Coupling Reactions provides a complete up-to-date collection of the available reactions and catalytic systems for the formation of carbon-heteroatom and carbon-carbon bonds. This essential reference covers a broad scope of copper-mediated reactions, their variations, key advances, improvements, and an array of academic and industrial applications that have revolutionized the field of organic synthesis. The text also discusses the mechanism of these transformations, the use of copper as cost-efficient alternative to palladium, as well as recently developed methods for conducting copper-mediated reactions with supported catalysts.

Autor

GWILHERM EVANO is a Professor at the Universite Libre de Bruxelles and the Co-Director of the Laboratory of Organic Chemistry. Prof. Evano's research focuses on the development of copper-mediated transformations, chemistry of ynamides and other hetero-substituted alkynes, and total synthesis of natural products. NICOLAS BLANCHARD is Research Director at the French National Center for Scientific Research at the University of Strasbourg. Dr. Blanchard's research interests focus on the synthesis of biologically relevant compounds using metal-mediated transformations.

Inhalt

Preface: Copper Catalysis from a Historical Perspective: A Legacy from the Past Gwilherm Evano and Nicolas Blanchard PART 1 FORMATION OF C-HETEROATOM BONDS Chapter 1: Modern Ullmann-Goldberg Chemistry: Arylation of N-nucleophiles with Aryl Halides Yongwen Jiang and Dawei Ma Chapter 2: Ullmann Condensation Today: Arylation of Alcohols and Thiols with Aryl Halides Anis Tlili and Marc Taillefer Chapter 3: Copper-Catalyzed Formation of C-P Bonds with Aryl Halides Carole Alayrac and Annie-Claude Gaumont Chapter 4: Alternative and Emerging Reagents for the Arylation of Heteronucleophiles Luc Neuville Chapter 5: Beyond Ullmann-Goldberg Chemistry: Vinylation, Alkynylation and Allenylation of Heteronucleophiles Kevin Jouvin and Gwilherm Evano Chapter 6: Aromatic/Vinylic Finkelstein Reaction Alicia Casitas and Xavi Ribas Chapter 7: Insights into the Mechanism of Modern Ullmann-Goldberg Coupling Reactions Alicia Casitas and Xavi Ribas PART 2 FORMATION OF C-C BONDS Chapter 8: Modern Copper-Catalyzed Hurtley Reaction: Efficient C-Arylation of CH-Acid Derivatives Irina P Beletskaya and Alexey Yu Fedorov Chapter 9: Copper-Catalyzed Cyanations of Aryl Halides and Related Compounds Thomas Schareina and Matthias Beller Chapter 10: Copper-Mediated Aryl--aryl Bond Formation Leading to Biaryls: A Century after the Ullmann Breakthrough Yoshihiko Yamamoto Chapter 11: Copper-Catalyzed Alkynylation, Alkenylation and Allylation Reactions of Aryl Derivatives Ren-Jie Song and Jin-Heng Li Chapter 12: Copper-Catalyzed Alkynylation and Alkenylation Reaction of Alkynyl Derivatives: New Access to Diynes and Enynes Ruimao Hua Chapter 13: Copper-Mediated Alkenylation Reaction of Alkenyl Derivatives: a Straightforward Elaboration of 1,3-Dienes Hao Li, Songbai Liu, and Lanny S Liebeskind Chapter 14: Emerging Areas in Copper-Mediated Trifluoromethylations of Aryl Derivatives: Catalytic and Oxidative Cross-Coupling Processes Kevin Jouvin, Celine Guissart, Cedric Theunissen and Gwilherm Evano PART 3 APPLICATIONS OF COPPER-CATALYZED CROSS-COUPLING REACTIONS: HETEROCYCLES, NATURAL PRODUCTS, PROCESS AND SUSTAINABLE CHEMISTRY Chapter 15: Copper-Mediated Cyclization Reactions: New Entries to Heterocycles Daoshan Yang and Hua Fu Chapter 16: Application of Copper-Mediated C--N Bond Formation in Complex Molecules Synthesis Jihoon Lee and James S Panek Chapter 17: Natural Products and C-O/C-S Bond Forming Reactions: Copper Showed the Way Doron Pappo Chapter 18: Copper-Catalyzed C-C Bond Formation in Natural Product Synthesis: Elegant and Efficient Solutions to a Key Bond Disconnection Morgan Donnard and Nicolas Blanchard Chapter 19: Process Chemistry and Copper Catalysis Klaus Kunz and Norbert Lui Chapter 20: Reusable Catalysts for Copper-Mediated Cross-Coupling Reactions under Heterogeneous Conditions Zhiyong Wang, Changfeng Wan and Ye Wang

Produkt-Details

• Erscheint lt. Verlag: 7.10.2013
• Verlagsort: New York
• Sprache: englisch
• Maße: 150 x 250 mm
• Gewicht: 666 g
• Themenwelt: Naturwissenschaften ► Chemie ► Physikalische Chemie
• ISBN-10: 1-118-69065-6 / 1118690656
• ISBN-13: 978-1-118-69065-9 / 9781118690659
• Zustand: Neuware