Ivermectin and Abamectin

Buch | Softcover

363 Seiten

2011 | Softcover reprint of the original 1st ed. 1989
Springer-Verlag New York Inc.
978-1-4612-8184-9 (ISBN)

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Ivermectin and abamectin, members of the avermectin family of compounds, were introduced to the market in the 1980's as a veterinary antiparasitic drug and agricultural pesticide, respectively. Their acceptance and commercial success have been remarkable; both are highly effective and in worldwide use. The efficacy of ivermectin in river blindness has expanded the interest in its use in human medicine. In response to the intense scientific and industrial interest in ivermectin and abamectin and the likelihood that they will be forerunners of an expanding family of drugs, this comprehensive monograph satisfies the need for a review and synthesis of current knowledge about the use of these substances in crop protection as well as in cattle, sheep, swine, horses, dogs, cats, birds, fish, reptiles, and in man. This overview presents chemical, biochemical, and microbiological data, as well as pharmacological, safety, and environmental aspects and covers practical use of the compounds as antiparasitic and pesticide agents, as well as the available safety data that have emerged from the clinical experience with human applications.

I.- 1. Chemistry.- 2. Isolation and Characterization of the Producing Organism.- 3. Fermentation Development and Process Improvement.- 4. Biosynthesis.- 5. Mode of Action of Ivermectin.- II.- 6. Toxicology.- 7. Pharmacokinetics of Ivermectin in Animals and Humans.- 8. Metabolism and Tissue Residues.- 9. Chemical Assay for Ivermectin in Edible Tissues.- 10. Safety of Ivermectin in Target Animals.- 11. Environmental Aspects of Ivermectin Usage in Livestock: General Considerations.- 12. Environmental Aspects of Use of Ivermectin and Abamectin in Livestock: Effects on Cattle Dung Fauna.- 13. Environmental Aspects of Abamectin Use in Crop Protection.- 14. Worker Safety Aspects of Abamectin Use in Crop Protection.- III.- 15. Use of Ivermectin in Cattle, Sheep, Goats, and Swine.- 16. Use of Abamectin in Cattle..- 17. Use of Ivermectin in Horses.- 18. Use of Ivermectin in Dogs and Cats.- 19. Use of Ivermectin in Laboratory and Exotic Mammals and in Birds, Fish, and Reptiles.- 20. Abamectin Use in Crop Protection.- 21. Use of Ivermectin in Humans.

Zusatzinfo	XX, 363 p.
Verlagsort	New York, NY
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Medizin / Pharmazie ► Allgemeines / Lexika
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Mikrobiologie / Infektologie / Reisemedizin
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
	Naturwissenschaften ► Biologie ► Ökologie / Naturschutz
	Naturwissenschaften ► Biologie ► Zoologie
	Weitere Fachgebiete ► Land- / Forstwirtschaft / Fischerei
ISBN-10	1-4612-8184-9 / 1461281849
ISBN-13	978-1-4612-8184-9 / 9781461281849
Zustand	Neuware