Solid-Phase Organic Synthesis
Wiley-Interscience (Verlag)
978-0-471-31825-5 (ISBN)
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Solid-Phase Organic Synthesis Edited by Kevin Burgess, Texas A & M University Efficient, high-throughput chemistry is now the focus of many research laboratories. Solid-phase organic syntheses are central to many of these combinatorial and parallel screening methodologies. Consequently, they have been a major scientific theme of the 1990s and promise to remain prominent for the first part of the new millennium. Indeed, a bewildering number of papers have entered the literature on this topic; some report minor modifications enabling transformation of solution-phase methods to a solid support, while others report major innovations. Solid-Phase Organic Synthesis collects, highlights, and critiques some of the key developments in the field. Leading practitioners explain different perspectives on diverse aspects of the area. Specific topics covered include:
* Syntheses of guanidines
* Palladium-catalyzed C-C bond forming reactions
* S_nAr reactions for the formation of heterocycles
* Sequence-specific arylalkyne oligomers
* Resin-supported capture agents and other reagents
* Synthesis on pins
* Monitoring of supported reactions using IR
* Solid-phase syntheses of natural product derivatives
Of related interest . Combinatorial Chemistry and Molecular Diversity in Drug Discovery Eric M. Gordon and James F. Kerwin 1998 (0-471-15518-7) 544 pp. Combinatorial Chemistry Synthesis and Application Stephen R. Wilson and Anthony W. Czarnik 1997 (0-471-12687-X) 288 pp.
Kevin Burgess FRSC is a British chemist who has been Rachal Professor of Chemistry at Texas A&M University since 2004. He was educated at the University of Bath, the University of East Anglia and Darwin College, Cambridge.
Solid Phase Syntheses of Guanidines (K. Burgess & J. Chen).
Palladium-catalyzed Carbon-carbon Bond Formation on Solid Supports (M. Todd & C. Abell).
Benzofused Heterocycles via Solid-phase S_NAr Reactions (M. Schwarz & M. Gallop).
Solid-phase Synthesis of Sequence-specific Phenylacetylene Oligomers (J. Moore, et al.).
Polymer-assisted Solution Phase Methods for Chemical Library Synthesis (D. Flynn, et al.).
Solid-phase Organic Synthesis on Radiation-grafted Polymer Surfaces: Application of SynPhase(TM) Crowns to Multiple Parallel Syntheses (I. James, et al.).
Vibrational Spectroscopy for Optimization of Solid-phase Organic Syntheses (B. Yan).
Recent Advances in Solid-phase Synthesis of Natural Products (L. Wilson).
| Erscheint lt. Verlag | 16.12.1999 |
|---|---|
| Sprache | englisch |
| Maße | 161 x 240 mm |
| Gewicht | 608 g |
| Einbandart | gebunden |
| Themenwelt | Naturwissenschaften ► Chemie ► Organische Chemie |
| ISBN-10 | 0-471-31825-6 / 0471318256 |
| ISBN-13 | 978-0-471-31825-5 / 9780471318255 |
| Zustand | Neuware |
| Informationen gemäß Produktsicherheitsverordnung (GPSR) | |
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